Life Sciences

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HeadProf Alistair Mathie
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Preprint: Evolutionary dynamics of neoantigens in growing tumours

Other

Eszter Lakatos, Marc J. Williams, Ryan O. Schenck, William C. H. Cross, Jacob Househam, Benjamin Werner, Chandler Gatenbee, Mark Robertson-Tessi, Chris P. Barnes, Alexander R. A. Anderson, Andrea Sottoriva and Trevor A. Graham 2019. Preprint: Evolutionary dynamics of neoantigens in growing tumours. biorxiv.org. https://doi.org/10.1101/536433

Characterization and regulation of wild‐type and mutant TASK‐1 two pore domain potassium channels indicated in pulmonary arterial hypertension

Journal article

Cunningham, K.P., Holden, R.G., Escribano‐Subias, P.M., Cogolludo, A., Veale, E.L. and Mathie, A. 2019. Characterization and regulation of wild‐type and mutant TASK‐1 two pore domain potassium channels indicated in pulmonary arterial hypertension. Journal of Physiology. 597 (4), pp. 1087-1101. https://doi.org/10.1113/jp277275

The effect of brisk walking in the fasted versus fed state on metabolic responses, gastrointestinal function, and appetite in healthy men

Journal article

McIver, V.J., Mattin, L.R., Evans, G.H. and Yau, A.M.W. 2019. The effect of brisk walking in the fasted versus fed state on metabolic responses, gastrointestinal function, and appetite in healthy men. International Journal of Obesity. 43, pp. 1691-1700. https://doi.org/10.1038/s41366-018-0215-x

Diurnal influences of fasted and non-fasted brisk walking on gastric emptying rate, metabolic responses, and appetite in healthy males

Journal article

McIver, V.J., Mattin, L.R., Evans, G.H. and Yau, A.M.W. 2019. Diurnal influences of fasted and non-fasted brisk walking on gastric emptying rate, metabolic responses, and appetite in healthy males. Appetite. 143 104411. https://doi.org/10.1016/j.appet.2019.104411

C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

Journal article

Faravelli, G., Raimondi, S., Marchese, L., Partridge, F.A., Soria, C., Mangione, P.P., Canetti, D., Perni, M., Aprile, F.A., Zorzoli, I., Di Schiavi, E., Lomas, D.A., Bellotti, V., Sattelle, D.B. and Giorgetti, S. 2019. C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis. Scientific Reports. 9 19960. https://doi.org/10.1038/s41598-019-56498-5

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies

Journal article

Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M.A., Hayward, R., Ahmad, S.M., Vizcay-Barrena, G., Protti, A., Zammit, P.S., dos Remedios, C.G., Ehler, E., Shah, A.M. and Shanahan, C.M. 2019. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies. JCI Insight. 4 (22) e126315. https://doi.org/10.1172/jci.insight.126315

Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report

Journal article

Daniel Brayson, Alessandra Frigiola and James E. Clark 2019. Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report. Experimental Physiology. 104 (2), pp. 174-179. https://doi.org/10.1113/ep087341

Vascular Biology of Superoxide-Generating NADPH Oxidase 5—Implications in Hypertension and Cardiovascular Disease

Journal article

Rhian M. Touyz, Aikaterini Anagnostopoulou, Livia L. Camargo, Francisco J. Rios and Augusto C. Montezano 2019. Vascular Biology of Superoxide-Generating NADPH Oxidase 5—Implications in Hypertension and Cardiovascular Disease. Antioxidants and Redox Signaling. 30 (7), pp. 1027-1040. https://doi.org/10.1089/ars.2018.7583

NOX5: Molecular biology and pathophysiology

Journal article

Rhian Touyz, Aikaterini Anagnostopoulou, Francisco Rios, Augusto C. Montezano and Livia L. Camargo 2019. NOX5: Molecular biology and pathophysiology. Experimental Physiology. 104 (5), pp. 605-616. https://doi.org/10.1113/ep086204

Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease

Other

Lange, S. and Nicholas, A.P. 2019. Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease. MDPI.

Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA

Book chapter

Mehta, K. and Patel, V.B. 2019. Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA. in: Hancock, J. and Conway, M.E. (ed.) Redox mediated Siganl Transduction. Methods in Molecular Biology New York Humana Press.

A comparison of two widely used physical activity monitoring methods to determine physical activity rates of University employees

Conference paper

Safi, A., Cole, M. and Walker, N. 2019. A comparison of two widely used physical activity monitoring methods to determine physical activity rates of University employees. Public Health Institution Conference. Liverpool John Moore University 04 Jul 2018

The importance of engaging in regular physical activity on health and wellbeing

Conference item

Safi, A. 2019. The importance of engaging in regular physical activity on health and wellbeing. RESFEST Annual Conference. Birmingham City University 03 Jul 2019

Physical activity, health and well-being interventions in the university workplace

Conference item

Safi, A. 2019. Physical activity, health and well-being interventions in the university workplace. 14th Annual Health Conference. Birmingham City University, UK 02 Jul 2019

Promoting Physical Activity Amongst University Employees

Conference item

Safi, A., Kelly, A.L., Cole, M. and Walker, N. 2019. Promoting Physical Activity Amongst University Employees. British Psychological Society (BPS) 2019 Annual Conference. Voco St. John’s Solihull, UK 02 - 03 Dec 2019

An evaluation of physical activity levels amongst university employees

Conference item

Safi, A., Cole, M., Walker, N. and Kelly, A.L. 2019. An evaluation of physical activity levels amongst university employees. British Association Sport and Exercise Sciences (BASES) 2019 Annual Conference. King Power Stadium, Leicester, UK 19 - 20 Nov 2019

The researcher on a mission to get staff exercising in the office

Other

Safi, A. 2019. The researcher on a mission to get staff exercising in the office. Birmingham City University Press Office.

Blog post: Ramadan: Fitness Survival Guide

Other

Safi, A. 2019. Blog post: Ramadan: Fitness Survival Guide. Birmingham City University.

How to fast responsibly during the Muslim holy month

Other

Safi, A. 2019. How to fast responsibly during the Muslim holy month. The Independent.

The Conversation: Ramadan: four tips to help you eat right and stay healthy

Other

Safi, A. 2019. The Conversation: Ramadan: four tips to help you eat right and stay healthy. The Conversation.

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation

Journal article

Watson, Jayne L., Sanchez-Garrido, Julia, Goddard, Philippa J., Torraca, V., Mostowy, Serge, Shenoy, Avinash R. and Clements, Abigail 2019. Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation. mBio. 10 (6) e02654-19. https://doi.org/10.1128/mbio.02654-19

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Journal article

Vincenzo Torraca, Myrsini Kaforou, Jayne Watson, Gina M. Duggan, Hazel Guerrero-Gutierrez, Sina Krokowski, Michael Hollinshead, Thomas B. Clarke, Rafal J. Mostowy, Gillian S. Tomlinson, Vanessa Sancho-Shimizu, Abigail Clements and Serge Mostowy 2019. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLOS Pathogens. 15 (12) e1008006. https://doi.org/10.1371/journal.ppat.1008006

RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection

Journal article

Rougeot, Julien, Torraca, V., Zakrzewska, Ania, Kanwal, Zakia, Jansen, Hans J., Sommer, Frida, Spaink, Herman P. and Meijer, Annemarie H. 2019. RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection. Frontiers in Immunology. 10 832. https://doi.org/10.3389/fimmu.2019.00832

CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells

Journal article

Annemarie Meijer and Torraca, V. 2019. CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells. Scientific Reports. 9 2399. https://doi.org/10.1038/s41598-019-38643-2

Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model

Journal article

Masud, Samrah, Prajsnar, Tomasz K., Torraca, V., Lamers, Gerda E. M., Benning, Marianne, Van der Vaart, Michiel and Meijer, Annemarie H. 2019. Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model. Autophagy. 15 (5), pp. 796-812. https://doi.org/10.1080/15548627.2019.1569297

Meeting report: Zebrafish Infection and Immunity 2019

Journal article

Torraca, V., Gomes, Margarida C., Sarris, Milka and Mostowy, Serge 2019. Meeting report: Zebrafish Infection and Immunity 2019. Lab Animal. 48, pp. 284-287. https://doi.org/10.1038/s41684-019-0400-0

Mechanisms into the development of fatty liver disease: role of bile acids, Betaine and MHY908

PhD thesis

Khalid, Q. 2019. Mechanisms into the development of fatty liver disease: role of bile acids, Betaine and MHY908. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/v291w

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

Journal article

Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, A., Pazoki, R., Suzuki, H., Koskeridis, F., Yiorkas, A., Karaman, I., Elliott, J., Luo, Q., Aeschbacher, S., Bartz, T., Baumeister, S., Braund, P., Brown, M., Brody, J., Clarke, T., Dimou, N., Faul, J., Homuth, G., Jackson, A., Kentistou, K., Joshi, P., Lemaitre, R., Lind, P., Lyytikäinen, L., Mangino, M., Milaneschi, Y., Nelson, C., Nolte, I., Perälä, M., Polasek, O., Porteous, D., Ratliff, S., Smith, J., Stančáková, A., Teumer, A., Tuominen, S., Thériault, S., Vangipurapu, J., Whitfield, J., Wood, A., Yao, J., Yu, B., Zhao, W., Arking, D., Auvinen, J., Liu, C., Männikkö, M., Risch, L., Rotter, J., Snieder, H., Veijola, J., Blakemore, A., Boehnke, M., Campbell, H., Conen, D., Eriksson, J., Grabe, H., Guo, X., van der Harst, P., Hartman, C., Hayward, C., Heath, A., Jarvelin, M., Kähönen, M., Kardia, S., Kühne, M., Kuusisto, J., Laakso, M., Lahti, J., Lehtimäki, T., McIntosh, A., Mohlke, K., Morrison, A., Martin, N., Oldehinkel, A., Penninx, B., Psaty, B., Raitakari, O., Rudan, I., Samani, N., Scott, L., Spector, T., Verweij, N., Weir, D., Wilson, J., Levy, D., Tzoulaki, I., Bell, J.D., Matthews, P., Rothenfluh, A., Desrivières, S., Schumann, G. and Elliott, P. 2019. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. 3 (9), pp. 950-961. https://doi.org/10.1038/S41562-019-0653-Z

Griseofulvin solvate solid dispersions with synergistic effect against fungal biofilms

Journal article

Al-Obaidi, H., Kowalczyk, R.M., Kalgudi, R. and Zariwala, M. 2019. Griseofulvin solvate solid dispersions with synergistic effect against fungal biofilms. Colloids and Surfaces B: Biointerfaces. 184 110540. https://doi.org/10.1016/j.colsurfb.2019.110540

Infrared Spectroscopic Detection of Biosignatures at Lake Tírez, Spain: Implications for Mars

Journal article

Preston, L.J., Barcenilla, R., Dartnell, L., Kucukkilic-Stephens, E. and Olsson-Francis, K. 2019. Infrared Spectroscopic Detection of Biosignatures at Lake Tírez, Spain: Implications for Mars. Astrobiology. 20 (1), pp. 15-25. https://doi.org/10.1089/ast.2019.2106

Understanding the role of different strain types of Fusobacterium necrophorum: biofilms, glycans and metabolic pathways

PhD thesis

Brimah, K. 2019. Understanding the role of different strain types of Fusobacterium necrophorum: biofilms, glycans and metabolic pathways. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/qzxy2

A transcriptomic and molecular approach uncovering ASCL2 as a novel tumourigenic gene in breast cancer

PhD thesis

Faramarzi, N. 2019. A transcriptomic and molecular approach uncovering ASCL2 as a novel tumourigenic gene in breast cancer. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/qzxxy

Stroke recovery in rats after 24h-delayed intramuscular neurotrophin-3 infusion

Journal article

Duricki, D.A., Drndarski, S., Bernanos, B., Tobias Wood, T., Bosch, K., Chen, Q., Shine, H.D., Simmons, C., Williams, S.C.R., McMahon, S.B., Begley, D.J., Cash, D. and Moon, L.D.F. 2019. Stroke recovery in rats after 24h-delayed intramuscular neurotrophin-3 infusion. Annals of Neurology. 85 (1), pp. 32-46. https://doi.org/10.1002/ana.25386

Investigations of Carbapenem-resistant Klebsiella species and associated clinical considerations

Prof Doc Thesis

Shibu, P. 2019. Investigations of Carbapenem-resistant Klebsiella species and associated clinical considerations. Prof Doc Thesis University of Westminster Life Sciences https://doi.org/10.34737/qz82z

Impact of the lipid-based nutrient supplements on prevention and treatment of childhood moderate undernutrition

Journal article

Oluwaniyi, .R., Keith, R., Alvarez, J-L. and Amorim. A.R. 2019. Impact of the lipid-based nutrient supplements on prevention and treatment of childhood moderate undernutrition. International Journal of Food, Nutrition and Public Health. 11 (1/2), pp. 1-25.

Tributes to Prof David Sanders

Journal article

Keith, R. 2019. Tributes to Prof David Sanders. World Nutrition. 10 (3), pp. 106-108. https://doi.org/10.26596/wn.2019103106-108

Microbial Proteomics

Book chapter

Patel, H. and Whitehouse, D. 2019. Microbial Proteomics. in: Rapley, R. and Whitehouse, D. (ed.) Genomics and Clinical Diagnostics The Royal Society of Chemistry. pp. 103-139

Prediction of ligands to universally conserved binding sites of the influenza A virus nuclear export protein

Journal article

Patel, H. and Kukol, A 2019. Prediction of ligands to universally conserved binding sites of the influenza A virus nuclear export protein. Virology. 537, pp. 97-103. https://doi.org/10.1016/j.virol.2019.08.013

Antibiotic-free antibacterial hydrogels for wound healing applications

PhD thesis

Orlando, I. 2019. Antibiotic-free antibacterial hydrogels for wound healing applications. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/qz084

Prostate Cancer: The role of inflammation and chemokines

Journal article

Rani, A., Dasgupta, P. and Murphy, J.J. 2019. Prostate Cancer: The role of inflammation and chemokines. American Journal of Pathology. 189 (11), pp. 2119-2137. https://doi.org/10.1016/j.ajpath.2019.07.007


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