Life Sciences

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Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features

Article

Wardle, N.J., Kalber, T., Bell, J.D. and Bligh, S.W.A. 2011. Synthesis and characterisation of a novel tubulin-directed DO3A–colchicine conjugate with potential theranostic features. Bioorganic and Medicinal Chemistry Letters. 21 (11), pp. 3346-3348. https://doi.org/10.1016/j.bmcl.2011.04.014

Poly-3-hydroxyoctanoate P(3HO), a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina

Article

Rai, R., Yunos, D.M., Boccaccini, A.R., Knowles, J.C., Barker, I.A., Howdle, S.M., Tredwell, G.D., Keshavarz, T. and Roy, I. 2011. Poly-3-hydroxyoctanoate P(3HO), a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina. Biomacromolecules. 12 (6), pp. 2126-2136. https://doi.org/10.1021/bm2001999

CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells

Article

Porakishvili, N., Memon, A., Vispute, K., Kulikova, N., Clark, E.A., Rai, K.R., Nathwani, A., Damle, R.N., Chiorazzi, N. and Lydyard, P.M. 2011. CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells. British Journal of Haematology. 153 (4), pp. 486-498. https://doi.org/10.1111/j.1365-2141.2011.08605.x

Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia

Article

Markiv, A., Peiris, D., Curley, G.P., Odell, M. and Dwek, M. 2011. Identification, cloning and characterization of two N-acetylgalactosamine binding lectins from the albumen gland of Helix pomatia. Journal of Biological Chemistry. 286 (23), pp. 20260-20266. https://doi.org/10.1074/jbc.M110.184515

A systematic review to assess the evidence of the positive and negative effects of Chinese herbal medicine in the treatment of depression

Article

Butler, L. and Pilkington, K. 2011. A systematic review to assess the evidence of the positive and negative effects of Chinese herbal medicine in the treatment of depression. European Journal of Integrative Medicine. 3 (2), pp. e111-e112. https://doi.org/10.1016/j.eujim.2011.04.011

Working at the (double-) edge

Article

Peters, D. 2011. Working at the (double-) edge. Journal of Holistic Healthcare. 8 (1), p. 2.

Enhanced intracellular Ca(2+) concentrations in Escherichia coli and Bacillus subtilis after addition of oligosaccharide elicitors

Article

Murphy, T., Nilsson, A., Roy, I., Harrop, A., Dixon, K. and Keshavarz, T. 2011. Enhanced intracellular Ca(2+) concentrations in Escherichia coli and Bacillus subtilis after addition of oligosaccharide elicitors. Biotechnology Letters. 33 (5), pp. 985-991. https://doi.org/10.1007/s10529-010-0511-6

Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future

Article

Rai, R., Keshavarz, T., Roether, J.A., Boccaccini, A.R. and Roy, I. 2011. Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future. Materials Science and Engineering R: Reports. 72 (3), pp. 29-47. https://doi.org/10.1016/j.mser.2010.11.002

Application of fluorescent indicators to analyse intracellular calcium and morphology in filamentous fungi

Article

Nair, R.R., Raina, S., Keshavarz, T. and Kerrigan, M.J.P. 2011. Application of fluorescent indicators to analyse intracellular calcium and morphology in filamentous fungi. Fungal Biology. 115 (4-5), pp. 326-334. https://doi.org/10.1016/j.funbio.2010.12.012

Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging

Article

Hankir, M., Parkinson, J.R.C., Minnion, J.S., Addison, M.L., Bloom, S.R. and Bell, J.D. 2011. Peptide YY3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging. Journal of Neuroendocrinology. 23 (4), pp. 371-380. https://doi.org/10.1111/j.1365-2826.2011.02111.x

Production of polyhydroxyalkanoates and their medical applications

Conference paper

Roy, I., Akaraonye, E., Francis, L., Rai, R., Basnett, P. and Keshavarz, T. 2011. Production of polyhydroxyalkanoates and their medical applications. 7th International Conference on Polymer and Textile Biotechnology. Milan, Italy 2nd - 4th March 2011

Module based antibody engineering: a novel synthetic REDantibody

Article

Markiv, A., Anani, B., Durvasula, R.V. and Kang, A.S. 2011. Module based antibody engineering: a novel synthetic REDantibody. Journal of Immunological Methods. 364 (1-2), pp. 40-49. https://doi.org/10.1016/j.jim.2010.10.009

Targeting the melanocortin receptor system for anti-stroke therapy

Article

Holloway, P.M., Smith, H.K., Renshaw, D., Flower, R.J., Getting, S.J. and Gavins, F.N.E. 2011. Targeting the melanocortin receptor system for anti-stroke therapy. Trends in Pharmacological Sciences. 32 (2), pp. 90-98. https://doi.org/10.1016/j.tips.2010.11.010

Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain

Article

Heindl, H., Greenwell, P., Weingarten, N., Kiss, T., Terstyanszky, G. and Weinzierl, R.O.J. 2011. Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain. Biochemical Society Transactions. 39 (1), pp. 31-35. https://doi.org/10.1042/BST0390031

Qualitative research in nutrition and dietetics: data collection issues

Article

Draper, A. and Swift, J.A. 2011. Qualitative research in nutrition and dietetics: data collection issues. Journal of Human Nutrition and Dietetics. 24 (1), pp. 3-12. https://doi.org/10.1111/j.1365-277X.2010.01117.x

Obesity and low vision as a result of excessive internet use, and television viewing

Article

Bener, A., Al-Mahdi, H.S., Ali, A.I., Al-Nufal, M., Vachhani, P.J. and Tewfik, I. 2011. Obesity and low vision as a result of excessive internet use, and television viewing. International Journal of Food Sciences and Nutrition. 62 (1), pp. 60-62. https://doi.org/10.3109/09637486.2010.495711

Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo

Article

Kenny, G., Kamaly, N., Kalber, T., Brody Leigh, Sahuri-Arisoylu Meliz, Shamsaei, E., Miller, A.D. and Bell, J.D. 2011. Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo. Journal of Controlled Release. 149 (2), pp. 111-116. https://doi.org/10.1016/j.jconrel.2010.09.020

Techniques for the Study of Apoptosis in Bone

Book chapter

Riahi, Sudeh, Noble, Brendon and Noble, B. 2011. Techniques for the Study of Apoptosis in Bone. in: Miep H. Helfrich and Stuart H. Ralston (ed.) Bone Research Protocols. 2nd edition Springer Nature. pp. 335-349

Collaborative project to co-ordinate care for patients with dementia.

Journal article

Kennerley, D., Bolas, R., Bourne, J., Branson, K., Cavenagh, P., Collins, G., Coveney, N., Day, N., Hardman, M., Hayter, S., Fenner, P., Jones, J., Jordan, S., Noble, B., Osbourne, S., Smith, C. and Wigens, L. 2011. Collaborative project to co-ordinate care for patients with dementia. Nursing Management. 18 (2), pp. 27-31. https://doi.org/10.7748/nm2011.05.18.2.27.c8484

Laser microdissection and pressure catapulting of single human motor neurons for RNA editing analysis

Book chapter

Sun, H., Raja, A., O’Connell, M.A., Mann, V., Noble, B. and Keegan, L.P. 2011. Laser microdissection and pressure catapulting of single human motor neurons for RNA editing analysis. in: RNA and DNA Editing: Methods and Protocols Humana Press. pp. 75–87

Blunting of adaptive responses to resistance exercise training in women over 75y

Journal article

Greig, C.A., Gray, C., Rankin, D., Young, A., Mann, V., Noble, B. and Atherton, P.J. 2011. Blunting of adaptive responses to resistance exercise training in women over 75y. Experimental Gerontology. 46 (11), pp. 884-890. https://doi.org/10.1016/j.exger.2011.07.010

Guide to Receptors and Channels (GRAC), 5th edition

Article

Alexander, S.P., Mathie, A. and Peters, J.A. 2011. Guide to Receptors and Channels (GRAC), 5th edition. British Journal of Pharmacology. 164 (S1). https://doi.org/10.1111/j.1476-5381.2011.01649_1.x

Artificial trans fatty acids in food supply: A global health threat

Journal article

Salomaa V.K. and Tewfik, I. 2011. Artificial trans fatty acids in food supply: A global health threat. World Journal of Science, Technology and Sustainable Development. 8 (4), pp. 361-401. https://doi.org/10.1108/20425945201100017

Can adult neural stem cells create New Brains? plasticity in the adult mammalian neurogenic niches: Realities and expectations in the Era of regenerative biology

Journal article

Kazanis, I. 2011. Can adult neural stem cells create New Brains? plasticity in the adult mammalian neurogenic niches: Realities and expectations in the Era of regenerative biology. The Neuroscientist. 18 (1), pp. 15-27. https://doi.org/10.1177/1073858410390379

The Number of Stem Cells in the Subependymal Zone of the Adult Rodent Brain is Correlated with the Number of Ependymal Cells and Not with the Volume of the Niche

Journal article

Kazanis, I. and ffrench-Constant, C. 2011. The Number of Stem Cells in the Subependymal Zone of the Adult Rodent Brain is Correlated with the Number of Ependymal Cells and Not with the Volume of the Niche. Stem Cells and Development. 21 (7). https://doi.org/10.1089/scd.2011.0130

Extracellular matrix and the neural stem cell niche

Article

Kazanis, I. 2011. Extracellular matrix and the neural stem cell niche. Developmental Neurobiology. 71 (11), pp. 1006-1017. https://doi.org/10.1002/dneu.20970

Trekking poles reduce exercise-induced muscle injury during mountain walking

Journal article

Howatson, G., Hough, P., Pattison, J., Hill, J., Blagrove, R., Glaister, M. and Thompson, Kevin G. 2011. Trekking poles reduce exercise-induced muscle injury during mountain walking. Medicine and Science in Sports and Exercise. https://doi.org/10.1249/mss.0b013e3181e4b649

Rapid reductions in left ventricular mass following a community based 12-week prevention programme are partially predicted by change in fat depots

Article

Jenni, S., Tillin, T., Park, C.M., Baker, M.D., Thomas, E.L., Bell, J.D., Connolly, S.B., Wood, D.A., Hughes, A.D. and Chaturvedi, N. 2011. Rapid reductions in left ventricular mass following a community based 12-week prevention programme are partially predicted by change in fat depots. European Heart Journal.

Mechanism for the Differential Effect of the Long-Acting Insulin Analog Detemir on Weight in Patients with Type 2 Diabetes

Article

Sheldon, Ben, Alsini, Najlaa, Zachariah, Sunil, Shojaee-Moradie, Fariba, Bodinham, Caroline, Robertson, Denise, Bell, Jimmy, Thomas, E. Louise, Vidal, Hubert, Meugnier, Emmanuelle, Jones, Richard H., Umpleby, A.M. and Russell-Jones, David 2011. Mechanism for the Differential Effect of the Long-Acting Insulin Analog Detemir on Weight in Patients with Type 2 Diabetes. Diabetes. 60 (Supplement 1), pp. A263-A264. https://doi.org/10.2337/db11-868-1281

Effects of 8 weeks oligofructose supplementation on appetite and body weight in overweight and obese adults

Article

Daud, N.M., Ismail, N., Thomas, E.L., Scholtz, S., Durighel, G., Fitzpatrick, J.A., Goldstone, A.P., Bell, J.D., Bech, P.R., Chambers, E., Chhina, N., Ghatei, M.A., Pedersen, C. and Frost, G.S. 2011. Effects of 8 weeks oligofructose supplementation on appetite and body weight in overweight and obese adults. Proceedings of the Nutrition Society. 70 (Issue OCE6: Winter Meeting, 6–7 December 2011, 70th Anniversary: Body weight regulation – food, gut and brain signalling) E374. https://doi.org/10.1017/s0029665111004599

Impact of liver fat on the response of plasma triacylglycerol to diets high and low in extrinsic sugars

Article

Ahmad, A., Isherwood, C., Bell, J. D., Thomas, E. L., Frost, G., Umpleby, M. and Griffin, B. A. 2011. Impact of liver fat on the response of plasma triacylglycerol to diets high and low in extrinsic sugars. Proceedings of the Nutrition Society. 70 (Issue OCE6: Winter Meeting, 6–7 December 2011, 70th Anniversary: Body weight regulation – food, gut and brain signalling) E364. https://doi.org/10.1017/s0029665111004496

PedVacc001: Safety and Immunogenicity of a Candidate HIV-1 Vaccine, MVA. HIVA, Administered to Healthy Gambian Infants Born to HIV-1/2-Uninfected Mothers

Conference item

Afolabi, M, Ndure, J, Mueller, J, Thomas, V, Shams-Rony, M, Borthwick, N, Bridgeman, A, Black, A, Reilly, M, Jaoko, W and others 2011. PedVacc001: Safety and Immunogenicity of a Candidate HIV-1 Vaccine, MVA. HIVA, Administered to Healthy Gambian Infants Born to HIV-1/2-Uninfected Mothers. AIDS Vaccine Conference. Bangkok, Thailand 12 - 15 Sep 2011

The Role of the Fc Region in CD70-specific Antibody Effects on Cardiac Transplant Survival

Journal article

Jurcevic, S., Shariff, H., Greenlaw, R.E., Meader, L., Gardner, N., Yagita, H., Coccia, M. and Mamode, N. 2011. The Role of the Fc Region in CD70-specific Antibody Effects on Cardiac Transplant Survival. Transplantation. 92 (11), pp. 1194-1201. https://doi.org/10.1097/TP.0b013e3182347ecd

Characterisation of T cells induced by candidate prophylactic vaccines encoding a HIV-1 conserved immunogen in phase I/IIa trial HIVCORE002

Conference item

Ahmed, T., Borthwick, N., Yang, H., Hancock, G., Yorke, L., Black, A., Ebrahimsa, U., Rose, A., Dorrell, L. and Hanke, T. 2011. Characterisation of T cells induced by candidate prophylactic vaccines encoding a HIV-1 conserved immunogen in phase I/IIa trial HIVCORE002. Annual Congress of the British Society for Immunology 2011. Liverpool, United Kingdom 05 - 08 Dec 2011

Comparison between serum insulin levels and its resistance with biochemical, clinical and anthropometric parameters in South Indian children and adolescents

Journal article

Srinivasa Nageswara, Rao G., Prema, G., Gururajan, P., Arumugam, S.B., Kirthivasan, V., Saibabu, R. and Cherian, K.M. 2011. Comparison between serum insulin levels and its resistance with biochemical, clinical and anthropometric parameters in South Indian children and adolescents. Indian Journal of Clinical Biochemistry. 26, pp. 22-27. https://doi.org/10.1007/s12291-010-0069-z

Plasma total nitric oxide and endothelial constitutive nitric oxide synthase (ecNOS) gene polymorphism: a study in a South Indian population.

Journal article

Gururajan, P., Gurumurthy, P., Victor, D., Srinivasa Nageswara, R.ao G, Sai Babu, R., Sarasa Bharati, A. and Cherian, K.M. 2011. Plasma total nitric oxide and endothelial constitutive nitric oxide synthase (ecNOS) gene polymorphism: a study in a South Indian population. Biochemical Genetics. 49, pp. 96-103. https://doi.org/10.1007/s10528-010-9391-7

Serum E-selectin levels in Indian children and adolescents: relation to clinical and biochemical parameters.

Journal article

Rao, G.S., Gurumurthy, P., Gururajan, P., Saibabu, R. and Cherian, K.M. 2011. Serum E-selectin levels in Indian children and adolescents: relation to clinical and biochemical parameters. Pediatrics International. 53 (1), pp. 40-45. https://doi.org/10.1111/j.1442-200x.2010.03191.x

Artemisinins act through at least two targets in a yeast model

Journal article

Moore, Catherine M., Hoey, Elizabeth M., Trudgett, Alan and Timson, David J. 2011. Artemisinins act through at least two targets in a yeast model. FEMS Yeast Research. 11 (2), pp. 233-237. https://doi.org/10.1111/j.1567-1364.2010.00706.x

Pathogenicity of Misfolded and Dimeric HLA-B27 Molecules

Journal article

Antoniou, A.N., Lenart, I. and Guiliano, D.B. 2011. Pathogenicity of Misfolded and Dimeric HLA-B27 Molecules. International Journal of Rheumatology. 2011 Article ID 486856. https://doi.org/10.1155/2011/486856

The Oxidative Folding and Misfolding of Human Leukocyte Antigen-B27

Journal article

Antoniou, A.N., Guiliano, D.B., Lenart, I., Burn, G. and Powis, S.J. 2011. The Oxidative Folding and Misfolding of Human Leukocyte Antigen-B27. Antioxidants and Redox Signaling. 15 (2), pp. 669-684. https://doi.org/10.1089/ars.2010.3692


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