Life Sciences

Osimo, E.F., Brugger, S.P., Thomas, E.L. and Howes, O.D. 2021. Preprint: Body fat volumes and distribution in chronic schizophrenia compared to healthy controls; a cross-sectional MR study. medRxiv. https://doi.org/10.1101/2021.09.20.21263820

Fuchs, Franziska E., Pauly, Maude, Black, Antony P., Hübschen, Judith M. and Black, Antony, P. 2021. Seroprevalence of ToRCH Pathogens in Southeast Asia. Microorganisms. 9 (3), p. 574. https://doi.org/10.3390/microorganisms9030574

Hefele, Lisa, Xaydalasouk, Kinnaly, Kleine, Daria, Homsana, Anousin, Xayavong, Dalouny, Syphan, Sengdavanh, Hübschen, Judith M., Muller, Claude P. and Black, Antony P. 2021. Seroprevalence of measles and rubella antibodies in vaccinated and unvaccinated infants in the Lao People’s Democratic Republic. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2021.06.016

Virachith, Siriphone, Pommelet, Virginie, Calvez, Elodie, Khounvisith, Vilaysone, Sayasone, Somphou, Kounnavong, Sengchanh, Mayxay, Mayfong, Xangsayarath, Phonepadith, Temmam, Sarah, Eloit, Marc, Escriou, Nicolas, Rose, Thierry, Vongphayloth, Khamsing, Hübschen, Judith M., Lacoste, Vincent, Somlor, Somphavanh, Phonekeo, Darouny, Brey, Paul T. and Black, Anthony 2021. Low seroprevalence of COVID-19 in Lao PDR, late 2020. The Lancet Regional Health -Western Pacific. 13 100197. https://doi.org/10.1016/j.lanwpc.2021.100197

Sarah O. John-Olabode, Kehinde S. Okunade, Ayorinde James, Gbenga Olorunfemi, Obiefuna I. Ajie, Akinniyi A. Osuntoki and Alani S. Akanmu 2021. Prevalence of Factor V Leiden G1691A and Prothrombin G20210A Gene Mutation Among Pregnant Women: Experience from a Multi-Center Study in Nigeria. Journal of Blood Medicine. 12, pp. 307-312. https://doi.org/10.2147/jbm.s308997

Kehinde S. Okunade, Adaiah Soibi-Harry, Sarah John-Olabode, Adebola A. Adejimi, Matthew J. Allsop, Tonia C. Onyeka, Godwin O. Akaba, Yusuf A. Oshodi, Omolola Salako, Aloy O. Ugwu, Ayodeji Adefemi, Rose I. Anorlu and Jonathan S. Berek 2021. Impact of Mobile Technologies on Cervical Cancer Screening Practices in Lagos, Nigeria (mHealth-Cervix): A Randomized Controlled Trial. JCO Global Oncology. 7, pp. 1418-1425. https://doi.org/10.1200/go.21.00258

Okunade, K.S., Olowoselu, O.F., John-Olabode, S., Hassan, B.O., Akinsola, O.J., Nwogu, C.M., Ugwu, A.O., Moses, O.E., Rabiu, K.A., Ajepe, A., Adenekan, M.A., Adejimi, A.A., Akanmu, S.A. and Kanki, P.J. 2021. Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial. International Journal of Gynecology & Obstetrics. 153 (3), pp. 533-541. https://doi.org/10.1002/ijgo.13514

John-Olabode, S.O., Okunade, K.S., Ajie, I.O., Olorunfemi, G. and Oyedeji, O.A. 2021. Awareness and practice of cord blood donation by pregnant women in Lagos Nigeria: Practice implication for future cord blood transplantation in Nigeria. Annals of African Medicine. 20 (1), pp. 24-30. https://doi.org/10.4103/aam.aam_9_20

Hefele, Lisa, Black, A., Van Tan, Trinh, Tri Minh, Nguyen, Duc Hoang, Nguyen, Virachith, Siriphone, Muller, Claude P, Hübschen, Judith M, Russell, Paula, Bartholdson Scott, Josefin, Chau Nguyen Ngoc Minh, Tran Vu Thieu Nga and Baker, Stephen 2021. An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao Peoplé s Democratic Republic. PLoS Neglected Tropical Diseases. 15 (12). https://doi.org/10.1371/journal.pntd.0010017

Khampanisong, Phonepaseuth, Pauly, Maude, Nouanthong, Phonethipsavanh, Vickers, Molly A, Virachith, Siriphone, Xaydalasouk, Kinnaly, Black, A., Muller, Claude P and Hübschen, Judith M 2021. Waning of maternal antibodies against measles suggests a large window of susceptibility in infants in Lao People’s Democratic Republic. Pathogens. 10 (10). https://doi.org/10.3390/pathogens10101316

Nouanthong, Phonethipsavanh, Hefele, Lisa, Keokhamphue, Jerapha, Sorrasin, Vonhphet, Khounvisith, Vilaysone, Souksakhone, Chanthala, Jutavijittum, Prapan, Muller, Claude P, Black, A. and Hübschen, Judith M 2021. Analyses of blood donor samples from eight provinces in Lao PDR suggest considerable variation concerning HBV exposure and carriage. PLoS ONE. 16 (12). https://doi.org/10.1371/journal.pone.0259814

Mangkara, Bouasone, Xaydalasouk, Kinnaly, Chanthavilay, Phetsavanh, Kounnavong, Sengchanh, Sayasone, Somphou, Muller, Claude P., Paboriboune, Phimpha and Black, Antony P. 2021. Hepatitis B virus in Lao dentists: a cross-sectional serological study. Annals of Hepatology. 22 100282. https://doi.org/10.1016/j.aohep.2020.10.010

Xaydalasouk, Kinnaly, Innoula, Nouna, Putthana, Vannaphone, Chanthavongsa, Korakan, Snoeck, Chantal J., Hübschen, Judith M., Oudomphone, Phommy, Chan, Bouangeun, Muller, Claude P. and Black, Antony P. 2021. High seroprevalence of Foot and Mouth Disease in Laos: Call for nationwide vaccination campaigns and disease surveillance. Transboundary and Emerging Diseases. 68 (4), pp. 2345-2352. https://doi.org/10.1111/tbed.13895

Snoeck, Chantal J., Evdokimov, Konstantin, Xaydalasouk, Kinnaly, Mongkhoune, Sodaly, Sausy, Aurélie, Vilivong, Keoudomphone, Pauly, Maude, Hübschen, Judith M., Billamay, Somxay, Muller, Claude P. and Black, Antony 2021. Epidemiology of acute respiratory viral infections in children in Vientiane, Lao People's Democratic Republic. Journal of Medical Virology. 93 (8), pp. 4748-4755. https://doi.org/10.1002/jmv.27004

Jones, A.R., Iacoangeli, A., Adey, B.N., Bowles, H., Shatunov, A, Troakes, C., Garson, J.A., McCormick, A.L. and Al‑Chalabi, A. 2021. A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex. Scientific Reports. 11 14283. https://doi.org/10.1038/s41598-021-93742-3

Corpas, Manuel, Beck, Stephan, Glusman, Gustavo and Shabani, Mahsa 2021. Editorial: Personal Genomes: Accessing, Sharing, and Interpretation. Frontiers in Genetics. 12 687584. https://doi.org/10.3389/fgene.2021.687584

Chu, J. 2021. The role of ERK5 signalling in macrophage behaviour during wound healing. PhD thesis University of Manchester Division of Pharmacy & Optometry

Hanieh Yaghootkar, Susan Martin, Jessica Tyrrell, Elizabeth Thomas, Matthew Bown, Andrew Wood, Robin Beaumont, Lam Tsoi, Philip E Stuart, James Elder, Philip Law, Richard Houlston, Christopher Kabrhel, Nikos Papadimitriou, Marc Gunter, Caroline Bull, Joshua Bell, Emma Vincent, Naveed Sattar, Jimmy Bell and Timothy Frayling 2021. Preprint: Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease. Research Square. https://doi.org/10.21203/rs.3.rs-537397/v1

El Zein, R. 2021. Dietary intakes in community-dwelling older adults during the COVID-19 outbreak. Proceedings of the Nutrition Society. 80 (OCE1), p. E18. https://doi.org/10.1017/s0029665121000197

Yuksel, Muhammed, Akturk, Hacer, Mizikoglu, Ozlem, Toroslu, Ertug and Arikan, Cigdem 2021. A single-center report of COVID-19 disease course and management in liver transplanted pediatric patients. Pediatric Transplantation. 25 (7) e14061. https://doi.org/10.1111/petr.14061

Yuksel, Muhammed, Armutlu, Ayse, Nazmi, Farinaz, Ceylaner, Serdar and Arikan, Cigdem 2021. A novel insight into the pathophysiology of autoimmune hepatitis: An immune activator mutation in the FLT3 receptor. Hepatology Forum. 2 (3), pp. 112-116. https://doi.org/10.14744/hf.2021.2021.0010

Ma, Yun, Su, Haibin, Yuksel, Muhammed, Longhi, Maria Serena, McPhail, Mark J., Wang, Pengyun, Bansal, Sanjay, Wong, Guan-Wee, Graham, Jonathon, Yang, Li, Thompson, Richard J., Doherty, Derek G., Hadzic, Nedim, Zen, Yoh, Quaglia, Alberto, Heneghan, Michael A., Samyn, Marianne, Vergani, Diego and Mieli-Vergani, Giorgina 2021. Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry. Hepatology. 74 (4), pp. 2032-2046. https://doi.org/10.1002/hep.31893

Yuksel, Muhammed, Demir, Baris, Mizikoglu, Ozlem, Akyildiz, Murat, Baygul, Arzu and Arikan, Cigdem 2021. Course of vitamin D levels before and after liver transplantation in pediatric patients. Pediatric Transplantation. 25 (7) e14049. https://doi.org/10.1111/petr.14049

Iben Lyskjær, Christopher Davies, Anna‐Christina Strobl, Joanna Hindley, Steven James, Radhesh K. Lalam, William Cross, Geoff Hide, Kenneth S. Rankin, Lee Jeys, Roberto Tirabosco, Jonathan Stevenson, Paul O’Donnell, Paul Cool, Adrienne M. Flanagan and Genomics England Research Consortium 2021. Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations. Molecular Oncology. 15 (12), pp. 3679-3690. https://doi.org/10.1002/1878-0261.13102

Michal Kovac, Baptiste Ameline, Sebastian Ribi, Monika Kovacova, William Cross, Maxim Barenboim, Olaf Witt, Stefan Bielack, Andreas Krieg, Wolfgang Hartmann, Michaela Nathrath and Daniel Baumhoer 2021. The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies. The Journal of Pathology. 254 (5), pp. 556-566. https://doi.org/10.1002/path.5699

Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J. van Roosmalen, Ana C.F. Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C.H. Cross, Nicolle Besselink, Bastiaan Van der Roest, Sander Boymans, Koen C. Oost, Sippe G. de Vries, Holger Rehmann, Edwin Cuppen, Susanne M.A. Lens, Geert Kops, Wigard P. Kloosterman, Leon Terstappen, Chris Barnes, Andrea Sottoriva, Trevor Graham and Hugo Snippert 2021. Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nature Genetics. 53, pp. 1187-1195. https://doi.org/10.1038/s41588-021-00891-2

William Cross, Iben Lyskjær, Tom Lesluyes, Steven Hargreaves, Anna-Christina Strobl, Christopher Davies, Sara Waise, Shadi Hames, Dahmane Oukrif, Hongtao Ye, Fernanda Amary, Roberto Tirabosco, Toby Baker, David Barnes, Christopher Steele, Ludmil Alexandrov, Gareth Bond, Paul Cool, Nischalan Pillay, Peter Van Loo and Adrienne M. Flanagan 2021. Preprint: A Genetic Model for Central Chondrosarcoma Evolution Correlates with Patient Outcome. medRxiv. https://doi.org/10.1101/2021.11.02.21265785

Cunningham, K., Clapp. L.H., Mathie, A. and Veale, E.L. 2021. The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels. Frontiers in Pharmacology. 12 705421. https://doi.org/10.3389/fphar.2021.705421

Mathie, A., Veale, E.L., Cunningham, K.P., Holden, R.G. and Wright, P.D. 2021. Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond. Annual Review of Pharmacology and Toxicology. 61, pp. 401-420. https://doi.org/10.1146/annurev-pharmtox-030920-111536

Staines, Henry M., Kirwan, Daniela E., Clark, David J., Adams, Emily R., Augustin, Yolanda, Byrne, Rachel L., Cocozza, Michael, Cubas-Atienzar, Ana I., Cuevas, Luis E., Cusinato, Martina, Davies, Benedict M.O., Davis, Mark, Davis, Paul, Duvoix, Annelyse, Eckersley, Nicholas M., Forton, Daniel, Fraser, Alice J., Garrod, Gala, Hadcocks, Linda, Hu, Qinxue, Johnson, Michael, Kay, Grant A, Klekotko, Kesja, Lewis, Zawditu, Macallan, Derek C., Mensah-Kane, Josephine, Menzies, Stefanie, Monahan, Irene, Moore, Catherine M., Nebe-von-Caron, Gerhard, Owen, Sophie I., Sainter, Chris, Sall, Amadou A., Schouten, James, Williams, Christopher T., Wilkins, John, Woolston, Kevin, Fitchett, Joseph R.A., Krishna, Sanjeev and Planche, Tim 2021. IgG Seroconversion and Pathophysiology in Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Emerging Infectious Diseases. 27 (1), pp. 85-91. https://doi.org/10.3201/eid2701.203074

Moore, Catherine M., Grandits, Melanie, Grünwald-Gruber, Clemens, Altmann, Friedrich, Kotouckova, Maria, Teh, Audrey Y-H and Ma, Julian K-C 2021. Characterisation of a highly potent and near pan-neutralising anti-HIV monoclonal antibody expressed in tobacco plants. Retrovirology. 18 17. https://doi.org/10.1186/s12977-021-00560-6

Catherine M. Moore, Jigang Wang, Qingsong Lin, Pedro Ferreira, Mitchell A. Avery, Khaled Elokely, Henry M. Staines and Sanjeev Krishna 2021. Preprint: Selective inhibition of PfATP6 by artemisinins and identification of new classes of inhibitors after expression in yeast. biorxiv.org. https://doi.org/10.1101/2021.10.27.466210

Chan, S.H.Y., Khatib, Y., Webley, S., Layton, D. and Salek, S. 2021. ISPE Annual Meeting Abstracts: A Systematic Review of Non-Small Cell Lung Cancer Treatment-Related Cardiotoxicity. Pharmacoepidemiology and Drug Safety. 30 (S1). https://doi.org/10.1002/pds.5305

Buckingham, S.D., Partridge, F.A., Poulton, B.C., S. Miller, B.S., McKendry, R.A., Lycett, G.J. and Sattelle, D.B. 2021. Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance. PLoS Neglected Tropical Diseases. 15 (6) e0008639. https://doi.org/10.1371/journal.pntd.0008639

Partridge, F.A., Bataille, C.J.R., Forman, R., Marriott, A.E., Forde-Thomas, J., Häberli, C., Dinsdale, R.L., O’Sullivan, J.D.B., Willis, N.J., Wynne, G.M., Whiteland, H., Archer, J., Steven, A., Keiser, J., Turner, J.D., Hoffmann, K.F., Taylor, M.J., Else, K.J., Russell, A.J. and Sattelle, D.B. 2021. Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS Infectious Diseases. 7 (5), pp. 1260-1274. https://doi.org/10.1021/acsinfecdis.1c00025

Partridge, F.A., Poulton, B.C., Lake, M.A.I., Lees, R.A., Mann, H-J., Lycett, G.J. and Sattelle, D.B. 2021. Preprint: Actions of camptothecin derivatives on larvae and adults of the arboviral vector Aedes aegypti. biorxiv.org. https://doi.org/10.1101/2021.09.06.458863

Partridge, F.A., Bataille, C.J.R., Forman, R., Marriott, A.E., Forde-Thomas, J., Cécile Häberli, C., Dinsdale, R.L., O’Sullivan, J.D.B., Willis, N.J., Wynne, G.M., Whiteland, H., Archer, J., Steven, A., Keiser, J., Turner, J.D., Hoffmann, K.F., Taylor, M.J., Else, K.J., Russell, A.J. and Sattelle, D.B. 2021. Preprint: Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni. biorxiv.org. https://doi.org/10.1101/2020.11.17.384933

Buckingham, S.D., Partridge, F.A., Poulton, B.C., Miller, B., McKendry, R.A., Lycett, G.J. and Sattelle, D.B. 2021. Preprint: Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance. biorxiv.org. https://doi.org/10.1101/2020.07.20.211946

Partridge, F.A., Poulton, B., Lake, M.A.I., Lees, R.A., Mann, H-J., Lycett, G. and Sattelle, D.B. 2021. Actions of Camptothecin Derivatives on Larvae and Adults of the Arboviral Vector Aedes aegypti. Molecules. 26 (20) 6226. https://doi.org/10.3390/molecules26206226

Henderson, M.E.T., Brayson, D. and Halsey, L.G. 2021. The cardio‐respiratory effects of passive heating and the human thermoneutral zone. Physiological Reports. 9 (16) e14973. https://doi.org/10.14814/phy2.14973