Life Sciences

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HeadProf Alistair Mathie
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Hepatitis A virus in Lao People’s Democratic Republic: Seroprevalence and risk factors

Journal article

Khounvisith, Vilaysone, Xaiyaphet, Xaipasong, Chanthavilay, Phetsavanh, Nouanthong, Phonethipsavanh, Vongphachanh, Bounta, Reinharz, Daniel, Muller, Claude P. and Black, Antony P. 2020. Hepatitis A virus in Lao People’s Democratic Republic: Seroprevalence and risk factors. The American Journal of Tropical Medicine and Hygiene. 103 (1), pp. 164-168. https://doi.org/10.4269/ajtmh.19-0451

Lasting benefit of infant hepatitis B vaccination in adolescents in the Lao People’s Democratic Republic

Journal article

Hefele, Lisa, Vannachone, Souphaphone, Khounvisith, Vilaysone, Nouanthong, Phonethipsavanh, Sayasone, Somphou, Kounnavong, Sengchang, Chanthavilay, Phetsavanh, Muller, Claude P. and Black, Antony P. 2020. Lasting benefit of infant hepatitis B vaccination in adolescents in the Lao People’s Democratic Republic. International Journal of Infectious Diseases. 93, pp. 217-223. https://doi.org/10.1016/j.ijid.2020.01.055

Association between maternal serum homocysteine concentrations in early pregnancy and adverse pregnancy outcomes

Journal article

Nwogu, C., Okunade, K., Adenekan, M., Sekumade, A., John-Olabode, S. and Oluwole, A. 2020. Association between maternal serum homocysteine concentrations in early pregnancy and adverse pregnancy outcomes. Annals of African Medicine. 19 (2), pp. 113-118. https://doi.org/10.4103/aam.aam_41_19

Prevalence of Rhesus C and D Alloantibodies among Rhesus-Negative Women of Child Bearing Age at a Tertiary Hospital in South-West Nigeria

Journal article

Otomewo, L., John-Olabode, S., Okunade, K., Olorunfemi, G. and Ajie, I. 2020. Prevalence of Rhesus C and D Alloantibodies among Rhesus-Negative Women of Child Bearing Age at a Tertiary Hospital in South-West Nigeria. Nigerian Journal of Clinical Practice. 23 (12), pp. 1759-1766. https://doi.org/10.4103/njcp.njcp_114_20

Prognostic impact of pretreatment thrombocytosis in epithelial ovarian cancer

Journal article

Okunade, K., Dawodu, O., Adenekan, M., Nwogu, C.M., Awofeso, O., Ugwu, A.O., Salako, O., John-Olabode, S., Olowoselu, O. and Anorlu, R. 2020. Prognostic impact of pretreatment thrombocytosis in epithelial ovarian cancer. Nigerian Journal of Clinical Practice. 23 (8), pp. 1141-1147. https://doi.org/10.4103/njcp.njcp_134_19

Seroprevalence of anti-tetanus antibodies in mothers and cord blood and associated factors in health-care settings in Lao People’s Democratic Republic

Journal article

Ounnavong, Phoumsavath, Chanthavilay, Phetsavanh, Khampanisong, Phonepaseuth, Reinharz, Daniel, Muller, Claude P and Black, A. 2020. Seroprevalence of anti-tetanus antibodies in mothers and cord blood and associated factors in health-care settings in Lao People’s Democratic Republic. Vaccine. 38 (5), pp. 1234-1240. https://doi.org/10.1016/j.vaccine.2019.11.007

Timeliness of immunisation with the pentavalent vaccine at different levels of the health care system in the Lao People’s Democratic Republic: A cross-sectional study

Journal article

Hefele, Lisa, Syphan, Sengdavanh, Xayavong, Dalouny, Homsana, Anousin, Kleine, Daria, Chanthavilay, Phetsavanh, Nouanthong, Phonethipsavanh, Xaydalasouk, Kinnaly, Phathammavong, Outavong, Billamay, Somxay, Xeuatvongsa, Anonh, Reinharz, Daniel, Black, Antony and Muller, Claude P. 2020. Timeliness of immunisation with the pentavalent vaccine at different levels of the health care system in the Lao People’s Democratic Republic: A cross-sectional study. PLoS ONE. https://doi.org/10.1371/journal.pone.0242502

Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer

Journal article

Green, D., Eyre, H., Singh, A., Taylor, T, J., Chu, J., Jeys, L., Sumathi, V., Coonar, A., Rassl, D., Babur, M., Forster, D., Alzabin, S., Ponthan, F., McMahon, A., Bigger, B., Reekie, T., Kassiou, M., Williams, K., Dalmay, T., Fraser, D, W. and Finegan, G, F. 2020. Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer. Oncogene. https://doi.org/10.1038/s41388-020-1379-0

Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection

Journal article

Yuksel, M., Akturk, H. and Arikan, C. 2020. Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection. European Journal of Gastroenterology and Hepatology. 32 (9), pp. 1251-1255. https://doi.org/10.1097/meg.0000000000001804

Measuring single cell divisions in human tissues from multi-region sequencing data

Journal article

Benjamin Werner, Jack Case, Marc Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George David Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Tomlinson, I., Chris Barnes, Trevor Graham and Andrea Sottoriva 2020. Measuring single cell divisions in human tissues from multi-region sequencing data. Nature Communications . 11 1035. https://doi.org/10.1038/s41467-020-14844-6

Subclonal reconstruction of tumors by using machine learning and population genetics

Journal article

Giulio Caravagna, Timon Heide, Marc Williams, Luis Zapata, Daniel Nichol, Ketevan Chkhaidze, William Cross, George David Cresswell, Benjamin Werner, Ahmet Acar, Louis Chesler, Chris Barnes, Guido Sanguinetti, Trevor Graham and Andrea Sottoriva 2020. Subclonal reconstruction of tumors by using machine learning and population genetics. Nature Genetics. 52, pp. 898-907. https://doi.org/10.1038/s41588-020-0675-5

Sarcoma and the 100,000 Genomes Project: our experience and changes to practice

Journal article

Sophie C Prendergast, Anna‐Christina Strobl, William Cross, Nischalan Pillay, Sandra J Strauss, Hongtao Ye, Daniel Lindsay, Roberto Tirabosco, Jane Chalker, Shazia S Mahamdallie, Alona Sosinsky, Adrienne M Flanagan, Fernanda Amary, RNOH Pathology Laboratory and Biobank Team and Genomics England Research Consortium 2020. Sarcoma and the 100,000 Genomes Project: our experience and changes to practice. The Journal of Pathology: Clinical Research. 6 (4), pp. 297-307. https://doi.org/10.1002/cjp2.174

Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer

Other

William Cross, Maximilian Mossner, Salpie Nowinski, George Cresswell, Abhirup Banerjee, Marc Williams, Laura Gay, Ann-Marie Baker, Christopher Kimberley, Hayley Davis, Pierre Martinez, Maria Traki, Viola Walther, Kane Smith, Giulio Caravagna, Sasikumar Amarasingam, George Elia, Alison Berner, Ryan Changho Choi, Pradeep Ramagiri, Ritika Chauhan, Nik Matthews, Jamie Murphy, Anthony Antoniou, Susan Clark, Jo-Anne Chin Aleong, Enric Domingo, Inmaculada Spiteri, Stuart AC McDonald, Darryl Shibata, Miangela M Lacle, Lai Mun Wang, Morgan Moorghen, Ian PM Tomlinson, Marco Novelli, Marnix Jansen, Alan Watson, Nicholas A Wright, John Bridgewater, Manuel Rodriguez-Justo, Hemant Kocher, Simon J Leedham, Andrea Sottoriva and Trevor A Graham 2020. Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer. biorxiv.org. https://doi.org/10.1101/2020.03.26.007138

Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels

Journal article

Kevin P. Cunningham, D. Euan MacIntyre, Alistair Mathie and Emma L. Veale 2020. Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels. Acta Physiologica. 228 (2) e13361. https://doi.org/10.1111/apha.13361

Preprint: Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration

Other

Adams, Emily, Augustin, Yolanda, Byrne, Rachel, Clark, David, Cocozza, Michael, Cubas-Atienzar, Ana, Cuevas, Luis, Cusinato, Martina, Davies, Benedict, Davis, Mark, Davis, Paul, Duvoix, Annelyse, Eckersley, Nicholas, Edwards, Thomas, Fletcher, Tom, Fraser, Alice, Garrod, Gala, Hadcocks, Linda, Hu, Qinxue, Johnson, Michael, Kay, Grant, Keymer, Katherine, Kirwan, Daniela, Klekotko, Kesja, Lewis, Zawditu, Mason, Jenifer, Mensah-Kane, Josie, Menzies, Stefanie, Monahan, Irene, Moore, Catherine, Nebe-von-Caron, Gerhard, Owen, Sophie, Planche, Tim, Sainter, Chris, Schouten, James, Staines, Henry, Turtle, Lance, Williams, Chris, Wilkins, John, Woolston, Kevin, Sall, Amadou Alpha, Fitchett, Joseph and Krishna, Sanjeev 2020. Preprint: Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration. medRxiv. https://doi.org/10.1101/2020.04.29.20082099

Preprint: Dynamics of IgG seroconversion and pathophysiology of COVID-19 infections

Other

Staines, Henry, Kirwan, Daniela, Clark, David, Adams, Emily, Augustin, Yolanda, Byrne, Rachel, Cocozza, Michael, Cubas-Atienzar, Ana, Cuevas, Luis, Cusinato, Martina, Davies, Benedict, Davis, Mark, Davis, Paul, Duvoix, Annelyse, Eckersley, Nicholas, Forton, Daniel, Fraser, Alice, Garrod, Gala, Hadcocks, Linda, Hu, Qinxue, Johnson, Michael, Kay, Grant, Klekotko, Kesja, Lewis, Zawditu, Macallan, Derek, Mensah-Kane, Josephine, Menzies, Stefanie, Monahan, Irene, Moore, Catherine, Nebe-von-Caron, Gerhard, Owen, Sophie, Sainter, Chris, Sall, Amadou, Schouten, James, Williams, Chris, Wilkins, John, Woolston, Kevin, Fitchett, Joseph, Krishna, Sanjeev and Planche, Tim 2020. Preprint: Dynamics of IgG seroconversion and pathophysiology of COVID-19 infections. medRxiv. https://doi.org/10.1101/2020.06.07.20124636

Preprint: Characterisation of a Highly Potent and Near Pan-Neutralising Anti-HIV Monoclonal Antibody Expressed in Tobacco Plants

Other

Catherine Margaret Moore, Melanie Grandits, Clemens Grünwald-Gruber, Friedrich Altmann, Maria Kotouckova, Audrey Y.H. Teh and Julian K.C. Ma 2020. Preprint: Characterisation of a Highly Potent and Near Pan-Neutralising Anti-HIV Monoclonal Antibody Expressed in Tobacco Plants. Research Square. https://doi.org/10.21203/rs.3.rs-104508/v1

Method Development and Validation for Establishing a Virtual HPLC Simulator (PharmAlliance Project)

Devices and products

Chan, S. 2020. Method Development and Validation for Establishing a Virtual HPLC Simulator (PharmAlliance Project).

Identification of Cardiotoxicity related to Cancer Treatments: A Systematic Review

Other

Chan, S., Khatib, Y., Webley, S., Layton, D. and Salek, S. 2020. Identification of Cardiotoxicity related to Cancer Treatments: A Systematic Review. National Institute for Health and Care Research.

A Comparison of Intermittent and Continuous Exercise Bouts at Different Intensities on Appetite and Postprandial Metabolic Responses in Healthy Men

Journal article

Lewis R. Mattin, Victoria J. McIver, Adora Mo Wah Yau, Lewis J. James and Gethin H. Evans 2020. A Comparison of Intermittent and Continuous Exercise Bouts at Different Intensities on Appetite and Postprandial Metabolic Responses in Healthy Men. Nutrients. 12 (8) 2370. https://doi.org/10.3390/nu12082370

Anthelmintic drug discovery: target identification, screening methods and the role of open science

Journal article

Partridge, F.A., Forman, R., Bataille, C.J.R., Wynne, G.M., Nick, M., Russell, A.J., Else, K.J. and Sattelle, D.B. 2020. Anthelmintic drug discovery: target identification, screening methods and the role of open science. Beilstein Journal of Organic Chemistry. 16, pp. 1203-1224. https://doi.org/10.3762/bjoc.16.105

Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape

Other

Brayson, D., Ehler, E., dos Remedios, C.G. and Shanahan, C.M. 2020. Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape. medRxiv. https://doi.org/10.1101/2020.08.14.20168310

Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement

Journal article

Brayson, D., Holohan, S-J., Bardswell, S.C., Arno, M., Lu, H., Jensen, H.K., Tran, P.K., Barallobre‐Barreiro, J., Mayr, M., dos Remedios, C.G., Tsang, V.T., Frigiola, A. and Kentish, J.C. 2020. Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association. 9 (16) e015342. https://doi.org/10.1161/jaha.119.015342

The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle

Journal article

Piccus, R. and Brayson, D. 2020. The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle. Biology Letters. 16 (7) 20200302. https://doi.org/10.1098/rsbl.2020.0302

Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection

Journal article

Srey, M.T., Taccogna, A., Oksov, Y., Lustigman, S., Tai, P-Y., Acord, J., Selkirk, M.E., Lamb, T.J. and Guiliano, D.B. 2020. Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection. PLoS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0008842

Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug conjugates (ADcs)

Journal article

Hoffmann, R.M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H., Marlow, R., McDonnell, J.M., Figini, M., Lacy, K.E., Tutt, A.J.N., Spicer, J.F., Thurston, D.E., Karagiannis, S.N. and Crescioli, S. 2020. Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug conjugates (ADcs). Scientific Reports. 10 (1), pp. 1-11. https://doi.org/10.1038/s41598-020-65860-x

Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel

Journal article

Rhéure Alves-Lopes, Karla B. Neves, Aikaterini Anagnostopoulou, Francisco J. Rios, Silvia Lacchini, Augusto C. Montezano and Rhian M. Touyz 2020. Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel. Hypertension. 75, pp. 139-149. https://doi.org/10.1161/hypertensionaha.119.13861

Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells

Journal article

Aikaterini Anagnostopoulou, Livia de Lucca Camargo, Daniel Rodrigues, Augusto C. Montezano and Rhian Touyz 2020. Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells. Scientific Reports. 10 17818. https://doi.org/10.1038/s41598-020-73751-4

Paralytic shellfish toxins and associated toxin profiles in bivalve mollusc shellfish from Argentina

Journal article

Alejandra B. Goya, Sophie Tarnovius, Robert G. Hatfield, Lewis Coates, Adam M. Lewis, Andrew D. Turner and Lewis, A. 2020. Paralytic shellfish toxins and associated toxin profiles in bivalve mollusc shellfish from Argentina. Harmful Algae. 99 101910. https://doi.org/10.1016/j.hal.2020.101910

Blog: Making the most of Ramadan during the COVID-19 pandemic

Other

Safi, A. 2020. Blog: Making the most of Ramadan during the COVID-19 pandemic. Birmingham City University.

An interpretable semi-supervised classifier using rough sets for amended self-labeling

Conference paper

Grau, I., Sengupta, D., Garcia Lorenzo, M.M. and Nowe, A. 2020. An interpretable semi-supervised classifier using rough sets for amended self-labeling. IEEE International Conference on Fuzzy Systems (FUZZ-IEEE 2020). Glasgow, UK 19 - 24 Jul 2020 IEEE . https://doi.org/10.1109/fuzz48607.2020.9177549

Cells, Tissues and Organs of the Immune System

Book chapter

Porakishvili, N. and Lydyard, P. 2020. Cells, Tissues and Organs of the Immune System. in: Male, D., Peebles, S. and Male, V. (ed.) Immunology (9th edition) Elsevier. pp. 14-44

Method of Food Preparation Influences Blood Glucose Response to a High-Carbohydrate Meal: A Randomised Cross-over Trial

Journal article

Hodges, C., Archer, F., Chowdhury, M., Evans, B.L., Ghelani, D.J., Mortoglou, M. and Guppy, F.M. 2020. Method of Food Preparation Influences Blood Glucose Response to a High-Carbohydrate Meal: A Randomised Cross-over Trial. Foods. 9 (1) 23. https://doi.org/10.3390/foods9010023

Elevated microRNA expression could be diagnostic biomarker for PDAC

Journal article

Mortoglou, M., Arisan, D., Ferreira, T., McCormick, A.L. and Uysal Onganer, P. 2020. Elevated microRNA expression could be diagnostic biomarker for PDAC. Pancreatology. 20 (8) e19. https://doi.org/10.1016/j.pan.2020.10.015

Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

Journal article

Rui Zhang, Monica Varela, Gabriel Forn-Cuní, Vincenzo Torraca, Michiel van der Vaart and Annemarie H. Meijer 2020. Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death and Disease. 11 277. https://doi.org/10.1038/s41419-020-2477-1

Shigella sonnei

Journal article

Vincenzo Torraca, Kathryn Holt and Serge Mostowy 2020. Shigella sonnei. Trends in Microbiology. 28 (8), pp. P696-697. https://doi.org/10.1016/j.tim.2020.02.011

Frontline Science: Antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish

Journal article

Sommer, Frida, Torraca, V., Kamel, Sarah M., Lombardi, Amber and Meijer, Annemarie H. 2020. Frontline Science: Antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish. Journal of Leukocyte Biology. 107 (2), pp. 185-203. https://doi.org/10.1002/jlb.2hi0119-006r

Chemokine Receptors and Phagocyte Biology in Zebrafish

Journal article

Sommer, Frida, Torraca, V. and Meijer, Annemarie H. 2020. Chemokine Receptors and Phagocyte Biology in Zebrafish. Frontiers in Immunology. 11 325. https://doi.org/10.3389/fimmu.2020.00325

Supplementary RNAseq dataset files

Dataset

Frida Sommer, Torraca, V. and Annemarie H. Meijer 2020. Supplementary RNAseq dataset files. Zenodo. https://doi.org/10.5281/zenodo.3833847

Analysis tools to quantify dissemination of pathology in zebrafish larvae

Journal article

David R. Stirling, Oniz Suleyman, Eliza Gil, Philip M. Elks, Vincenzo Torraca, Mahdad Noursadeghi and Gillian S. Tomlinson 2020. Analysis tools to quantify dissemination of pathology in zebrafish larvae. Scientific Reports. 10 3149. https://doi.org/10.1038/s41598-020-59932-1


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