Life Sciences

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HeadProf Alistair Mathie
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Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females

Journal article

Isabella D. Cooper, Yvoni Kyriakidou, Lucy Petagine, Kurtis Edwards, Adrian Soto-Mota, Kenneth Brookler and Bradley T. Elliott 2024. Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females. Biomedicines. 12 (7) 1553. https://doi.org/10.3390/biomedicines12071553

Accessibility & the Labster Student Experience: A Panel Discussion

Conference keynote

Mattin, L.R., Starnawska, M., Ulanski, M. and Liquori, T. 2024. Accessibility & the Labster Student Experience: A Panel Discussion. Science ImmersEd- Uplifting the science educator community . Virtual Conference 29 May 2024

Looking at the impact of Western diet on gut bacteria of ethnic minority

Conference keynote

Mujral, M. and Mattin, L.R. 2024. Looking at the impact of Western diet on gut bacteria of ethnic minority . The Health Research For All event. Camden Chinese Community Centre 08 Jun 2024

High-intensity continuous exercise elevates I-FABP2 levels equally across 30 and 60-minute durations in healthy males

Conference keynote

Mattin, L.R., McIver, V.J., Yau, A.M.W. and Evans, G.H. 2024. High-intensity continuous exercise elevates I-FABP2 levels equally across 30 and 60-minute durations in healthy males. Physiology in Focus 2024. Northumbria University, Newcastle-upon-Tyne, UK 02 - 04 Jul 2024

Doctors’ and nurses’ eating practices during shift work: Findings from a qualitative study

Journal article

Sum, K., Cheshire, A., Ridge, Damien T., Sengupta, D. and Deb, D.S. 2024. Doctors’ and nurses’ eating practices during shift work: Findings from a qualitative study. Proceedings of the Nutrition Society. 83 (OCE2), p. E204. https://doi.org/10.1017/s0029665124004282

Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer

Journal article

Hamzeh Kayhanian, William Cross, Suzanne E. M. van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie Baker, Daniel C. Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H. Hageman, Julian R. Buissant des Amorie, Josep Linares, Marjolijn J. L. Ligtenberg, Iris D. Nagtegaal, Miangela M. Laclé, Leon M. G. Moons, Lodewijk A. A. Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A. Graham, Manuel Rodriguez-Justo, Kai-Keen Shiu, Hugo J. G. Snippert, Marnix Jansen and Cross, W. 2024. Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer. Nature Genetics. 56, pp. 1420-1433. https://doi.org/10.1038/s41588-024-01777-9

Pathogens associated with seafood exports from Southeast Asia to the European Union: Analysis of the Rapid Alert System for Food and Feed (1997–2020)

Journal article

Odeyemi, O. A., Somorin, Y. M., Ateba, C. N., Onyeaka, H., Anyogu, A., Amin, M., Dewi, F. R., Stratev, D., Oko, J. O. and Kasan, N. A. 2024. Pathogens associated with seafood exports from Southeast Asia to the European Union: Analysis of the Rapid Alert System for Food and Feed (1997–2020). Bulgarian Journal of Veterinary Medicine. 27 (2), pp. 305-321. https://doi.org/10.15547/bjvm.2022-0026

Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer

Journal article

Altayeb Ahmed, Madeleine Cule, Jimmy D. Bell, Naveed Sattar and Hanieh Yaghootkar 2024. Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer. Journal of Hepatology. 81 (6), pp. p921-929. https://doi.org/10.1016/j.jhep.2024.06.030

Selective induction of senescence in cancer cells through near-infrared light treatment via mitochondrial modulation

Journal article

Kalampouka, I., Mould, R., Botchway, S., Mackenzie, A.M., Nunn, A., Thomas, E.L. and Bell, J.D. 2024. Selective induction of senescence in cancer cells through near-infrared light treatment via mitochondrial modulation. Journal of Biophotonics. 17 (8) e202400046. https://doi.org/10.1002/jbio.202400046

Low-coverage whole genome sequencing for a highly selective cohort of severe COVID-19 patients

Journal article

Renato Santos, Víctor Moreno-Torres, Ilduara Pintos, Octavio Corral, Carmen de Mendoza, Vicente Soriano and Manuel Corpas 2024. Low-coverage whole genome sequencing for a highly selective cohort of severe COVID-19 patients. Gigabyte. https://doi.org/10.46471/gigabyte.127

The human colon: Evidence for degenerative changes during aging and the physiological consequences

Journal article

Baidoo, N. and Sanger, G.J. 2024. The human colon: Evidence for degenerative changes during aging and the physiological consequences. Neurogastroenterology & Motility. e14848. Advanced online publication. https://doi.org/10.1111/nmo.14848

MD-1 downregulation is associated with reduced cell surface CD180 expression in CLL

Journal article

Edwards, K., Manoussaka, M., Sayed, U., Tsertsvadze, T., De Deyn, L., Nathwani, A., Gribben, J.G., Krysov, S., Volpi, E., Lydyard, P. and Porakishvili, N. 2024. MD-1 downregulation is associated with reduced cell surface CD180 expression in CLL. Leukemia Research. 143 107540. https://doi.org/10.1016/j.leukres.2024.107540

Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population

Journal article

Sumudu Rangika Samarasinghe, Seung‐been Lee, Manuel Corpas, Segun Fatumo, Henk‐Jan Guchelaar and Shivashankar H. Nagaraj 2024. Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population. Clinical Pharmacology & Therapeutics. 1164 (4), pp. 980-995. https://doi.org/10.1002/cpt.3309

Challenges of developing and delivering authentic assessments

Conference poster

Smith, C.L. 2024. Challenges of developing and delivering authentic assessments. Teaching and Learning Conference 2024: Future-Focused Education: Innovation, Inclusion, and Impact. Nottingham Trent University - City campus 02 - 04 Jul 2024 Advance HE.

Exploring the potential link between prostate cancer and magnetic fields

Journal article

Alwyn Dart, D., Koushyar, S. and Uysal Onganer, P. 2024. Exploring the potential link between prostate cancer and magnetic fields. Medical Hypotheses. 189 111384. https://doi.org/10.1016/j.mehy.2024.111384

Marine Science Can Contribute to the Search for Extra-Terrestrial Life

Journal article

Aguzzi, Jacopo, Cuadros, Javier, Dartnell, Lewis, Costa, Corrado, Violino, Simona, Canfora, Loredana, Danovaro, Roberto, Robinson, Nathan Jack, Giovannelli, Donato, Flögel, Sascha, Stefanni, Sergio, Chatzievangelou, Damianos, Marini, Simone, Picardi, Giacomo and Foing, Bernard 2024. Marine Science Can Contribute to the Search for Extra-Terrestrial Life. Life. 14 (6) 676. https://doi.org/10.3390/life14060676

MRI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease

Journal article

Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Jimmy D. Bell and E. Louise Thomas 2024. MRI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease. Obesity (Silver Spring). 32 (9), pp. 1699-1708. https://doi.org/10.1002/oby.24108

Investigating Inflammatory Pathways in Alcohol-Associated Liver Disease

PhD thesis

Petagine, Lucy 2024. Investigating Inflammatory Pathways in Alcohol-Associated Liver Disease. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/wq305

Healing the Healer: Exploring UK-based doctors’ and nurses’ nutrition and dietary behaviours within the workplace

PhD thesis

Sum, Kiu 2024. Healing the Healer: Exploring UK-based doctors’ and nurses’ nutrition and dietary behaviours within the workplace. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/wq300

Doctoral Research Project : Sustainable production of bacterial polymers

PhD thesis

Vecchiato, Vittoria 2024. Doctoral Research Project : Sustainable production of bacterial polymers. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/wq2zy

Prevalence of yaws and syphilis in the Ashanti region of Ghana and occurrence of H. ducreyi, herpes simplex virus 1 and herpes simplex virus 2 in skin lesions associated with treponematoses

Journal article

Agyekum Boaitey, Y., Alex Owusu-Ofori,, Amarachukwu Anyogu, Farhang Aghakhanian, Natasha Arora, Jonathan B. Parr, Philipp P. Bosshard, Saki Raheem and Pascale Gerbault 2024. Prevalence of yaws and syphilis in the Ashanti region of Ghana and occurrence of H. ducreyi, herpes simplex virus 1 and herpes simplex virus 2 in skin lesions associated with treponematoses. PLoS ONE. 19 (5) e0295088. https://doi.org/10.1371/journal.pone.0295088

TASK-3, two-pore potassium channels, contribute to circadian rhythms in the electrical properties of the suprachiasmatic nucleus and play a role in driving stable behavioural photic entrainment.

Journal article

Steponenaite, A., Lalic, T., Atkinson, L., Tanday, N., Brown, L., Mathie, A., Cader, Z.M. and Lall, G.S. 2024. TASK-3, two-pore potassium channels, contribute to circadian rhythms in the electrical properties of the suprachiasmatic nucleus and play a role in driving stable behavioural photic entrainment. Chronobiology International. 41 (6), pp. 802-816. https://doi.org/10.1080/07420528.2024.2351515

Challenges to hepatitis C virus testing and treatment in a rural setting of Lao People's Democratic Republic

Journal article

Akkhasith, D., Sayasone, S., Homsana, A., Huebschen, J.M., Virachith, S., Black, A. and Paboriboune, P. 2024. Challenges to hepatitis C virus testing and treatment in a rural setting of Lao People's Democratic Republic. Journal of Clinical and Experimental Hepatology. 14 (5) 101426.

Analysis of androgen receptor expression and activity in the mouse brain

Journal article

D. Alwyn Dart, Charlotte L. Bevan, Pinar Uysal Onganer and Wen Guo Jiang 2024. Analysis of androgen receptor expression and activity in the mouse brain. Scientific Reports. 14 11115. https://doi.org/10.1038/s41598-024-61733-9

Network pharmacology and molecular docking: Combined computational approaches to explore the antihypertensive potential of Fabaceae species

Journal article

Shahzadi, Z., Yousaf, Z., Anjum, I., Bilal, M., Yasin, H., Aftab, A., Booker, A., Ullah, R. and Bari, A. 2024. Network pharmacology and molecular docking: Combined computational approaches to explore the antihypertensive potential of Fabaceae species. Bioresources and Bioprocessing. 11 53. https://doi.org/10.1186/s40643-024-00764-6

Factors associated with hepatitis B vaccination in Laos: findings from the multiple indicator cluster surveys in 2011/12 and 2017.

Journal article

Dekker, Trude, Hefele, Lisa, Neven, Anouk, Hübschen, Judith M., Essink, Dirk R. and Black, Antony P. 2024. Factors associated with hepatitis B vaccination in Laos: findings from the multiple indicator cluster surveys in 2011/12 and 2017. The Lancet Regional Health -Western Pacific. 46 101059. https://doi.org/10.1016/j.lanwpc.2024.101059

Effect of Sustainably Sourced Protein Consumption on Nutrient Intake and Gut Health in Older Adults: A Systematic Review

Journal article

Jones, D., Celis-Morales, C., Gray, S.R., Morrison, D.J., Ozone, S.E., Jain, M., Mattin, L.R. and Burden, S. 2024. Effect of Sustainably Sourced Protein Consumption on Nutrient Intake and Gut Health in Older Adults: A Systematic Review. Nutrients. 16 (9) 1398. https://doi.org/10.3390/nu16091398

The Contribution of Genetic Sequencing Information to the Identification and Functional Characterization of Two-Pore Domain Potassium (K2P) Channels as Viable Therapeutic Targets

Book chapter

Alistair Mathie, Samuel R. Bourne, Rachel Forfar, Walter E. Perfect and Emma L. Veale 2024. The Contribution of Genetic Sequencing Information to the Identification and Functional Characterization of Two-Pore Domain Potassium (K2P) Channels as Viable Therapeutic Targets. in: Stephens, G. and Stevens, E. (ed.) Ion Channels as Targets in Drug Discovery Springer Nature. pp. 199-220

Culturing marine bacteria from UK sediment samples to design co-created student research projects and promote microbiology and genomics education

Conference paper

Percy, L. 2024. Culturing marine bacteria from UK sediment samples to design co-created student research projects and promote microbiology and genomics education. Smith, C.L. (ed.) Microbiology Society Annual Conference 2024. Edinburgh 08 - 11 Apr 2024 Microbiology Society.

Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA)

Journal article

Gancitano, G., Mucci, N., Stange, R., Ogal, M., Vimalanathan, S., Sreya, M., Booker, A., Hadj-Cherif, B., Albrich, W., Woelkart-Ardjomand, K., Kreft, S., Vanden Berghe, W., Hoexter, G., Schapowal, A. and Johnston, S.L. 2024. Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA). Antibiotics. 13 (4) 364. https://doi.org/10.3390/antibiotics13040364

Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism

Journal article

Wu, X, Cunningham, K.P., Bruening-Wright, A, Pandey, S and Larsson, H. P. 2024. Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism. International Journal of Molecular Sciences. 25 (8) 4309. https://doi.org/10.3390/ijms25084309

Genomic Analysis of uropathogenic E. coli strains in Egypt

Conference poster

Mohammed, M. 2024. Genomic Analysis of uropathogenic E. coli strains in Egypt. Microbiology Society Annual Conference 2024. Edinburgh 08 - 11 Apr 2024 Microbiology Society.

Alpha-synuclein pathology in the "weaver" mouse, a genetic model of dopaminergic denervation.

Journal article

Dimopoulou, Aggeliki, Panagiotakopoulou, Vasiliki, Mourtzi, Theodora, Kazanis, Ilias and Angelatou, Fevronia 2024. Alpha-synuclein pathology in the "weaver" mouse, a genetic model of dopaminergic denervation. microPublication biology. 2024, p. 10.17912/micropub.biology.001156. https://doi.org/10.17912/micropub.biology.001156

Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture

Journal article

Dimitrios Kakogiannis, Michaela Kourla, Dimitrios Dimitrakopoulos and Ilias Kazanis 2024. Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture. Cells. 13 (8) 668. https://doi.org/10.3390/cells13080668

Screening for atrial fibrillation in care homes using pulse palpation and the AliveCor Kardia Mobile® device: a comparative cross-sectional pilot study

Journal article

V. Savickas, A. J. Stewart, V. J. Short, A. Mathie, S. K. Bhamra, E. L. Veale and S. A. Corlett 2024. Screening for atrial fibrillation in care homes using pulse palpation and the AliveCor Kardia Mobile® device: a comparative cross-sectional pilot study. International Journal of Clinical Pharmacy. 46, pp. 529-535. https://doi.org/10.1007/s11096-023-01672-z

BRCA Mutations and MicroRNA Expression Patterns in the Peripheral Blood of Breast Cancer Patients

Journal article

Alavanda, Ceren, Dirimtekin, Esra, Mortoglou, Maria, Uysal Onganer, Pinar, Arslan Ates, Esra and Guney, Ahmet Ilter 2024. BRCA Mutations and MicroRNA Expression Patterns in the Peripheral Blood of Breast Cancer Patients. ACS Omega. 9 (15), pp. 17217-17228. https://doi.org/10.1021/acsomega.3c10086

Preprint: MRI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease

Other

Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Jimmy D. Bell and E. Louise Thomas 2024. Preprint: MRI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease. medRxiv. https://doi.org/10.1101/2024.03.27.24304957

The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes

Journal article

Cresswell, E., Basty, N., Atabaki-Pasdar, N., Karpe, F. and Pinnick, K.E. 2024. The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes. Biochemical Pharmacology. 223 116171. https://doi.org/10.1016/j.bcp.2024.116171

Learning Development as a collaborative discipline. Book review: Syska, A. and Buckley, C. (eds.) (2023) How to be a Learning Developer in higher education: critical perspectives, community and practice. Abingdon: Routledge

Book review

Sum, K. 2024. Learning Development as a collaborative discipline. Book review: Syska, A. and Buckley, C. (eds.) (2023) How to be a Learning Developer in higher education: critical perspectives, community and practice. Abingdon: Routledge. Journal of Learning Development in Higher Education. 30.

What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2023? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society

Journal article

Bonaccorsi-Riani, Eliano, Ghinolfi, Davide, Czigany, Zoltan, Dondossola, Daniele, Emamaullee, Juliet, Yuksel, Muhammed, Boteon, Yuri L., Al-Adra, David, Ho, Cheng-Maw, Abdelrahim, Maen, Pang, Li, Barbas, Andrew, Meier, Raphael, MacParland, Sonya, Sayed, Blayne Amir, Pavan-Guimaraes, Juliana, Brüggenwirth, Isabel M.A., Zarrinpar, Ali, Mas, Valeria R., Selzner, Markus, Martins, Paulo N. and Bhat, Mamatha 2024. What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2023? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society. Transplantation. 108 (5), pp. 1043-1052. https://doi.org/10.1097/tp.0000000000004980


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