Life Sciences

Benjamin Werner, Jack Case, Marc Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George David Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Tomlinson, I., Chris Barnes, Trevor Graham and Andrea Sottoriva 2020. Measuring single cell divisions in human tissues from multi-region sequencing data. Nature Communications . 11 1035. https://doi.org/10.1038/s41467-020-14844-6

Giulio Caravagna, Timon Heide, Marc Williams, Luis Zapata, Daniel Nichol, Ketevan Chkhaidze, William Cross, George David Cresswell, Benjamin Werner, Ahmet Acar, Louis Chesler, Chris Barnes, Guido Sanguinetti, Trevor Graham and Andrea Sottoriva 2020. Subclonal reconstruction of tumors by using machine learning and population genetics. Nature Genetics. 52, pp. 898-907. https://doi.org/10.1038/s41588-020-0675-5

Sophie C Prendergast, Anna‐Christina Strobl, William Cross, Nischalan Pillay, Sandra J Strauss, Hongtao Ye, Daniel Lindsay, Roberto Tirabosco, Jane Chalker, Shazia S Mahamdallie, Alona Sosinsky, Adrienne M Flanagan, Fernanda Amary, RNOH Pathology Laboratory and Biobank Team and Genomics England Research Consortium 2020. Sarcoma and the 100,000 Genomes Project: our experience and changes to practice. The Journal of Pathology: Clinical Research. 6 (4), pp. 297-307. https://doi.org/10.1002/cjp2.174

William Cross, Maximilian Mossner, Salpie Nowinski, George Cresswell, Abhirup Banerjee, Marc Williams, Laura Gay, Ann-Marie Baker, Christopher Kimberley, Hayley Davis, Pierre Martinez, Maria Traki, Viola Walther, Kane Smith, Giulio Caravagna, Sasikumar Amarasingam, George Elia, Alison Berner, Ryan Changho Choi, Pradeep Ramagiri, Ritika Chauhan, Nik Matthews, Jamie Murphy, Anthony Antoniou, Susan Clark, Jo-Anne Chin Aleong, Enric Domingo, Inmaculada Spiteri, Stuart AC McDonald, Darryl Shibata, Miangela M Lacle, Lai Mun Wang, Morgan Moorghen, Ian PM Tomlinson, Marco Novelli, Marnix Jansen, Alan Watson, Nicholas A Wright, John Bridgewater, Manuel Rodriguez-Justo, Hemant Kocher, Simon J Leedham, Andrea Sottoriva and Trevor A Graham 2020. Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer. biorxiv.org. https://doi.org/10.1101/2020.03.26.007138

Kevin P. Cunningham, D. Euan MacIntyre, Alistair Mathie and Emma L. Veale 2020. Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels. Acta Physiologica. 228 (2) e13361. https://doi.org/10.1111/apha.13361

Adams, Emily, Augustin, Yolanda, Byrne, Rachel, Clark, David, Cocozza, Michael, Cubas-Atienzar, Ana, Cuevas, Luis, Cusinato, Martina, Davies, Benedict, Davis, Mark, Davis, Paul, Duvoix, Annelyse, Eckersley, Nicholas, Edwards, Thomas, Fletcher, Tom, Fraser, Alice, Garrod, Gala, Hadcocks, Linda, Hu, Qinxue, Johnson, Michael, Kay, Grant, Keymer, Katherine, Kirwan, Daniela, Klekotko, Kesja, Lewis, Zawditu, Mason, Jenifer, Mensah-Kane, Josie, Menzies, Stefanie, Monahan, Irene, Moore, Catherine, Nebe-von-Caron, Gerhard, Owen, Sophie, Planche, Tim, Sainter, Chris, Schouten, James, Staines, Henry, Turtle, Lance, Williams, Chris, Wilkins, John, Woolston, Kevin, Sall, Amadou Alpha, Fitchett, Joseph and Krishna, Sanjeev 2020. Preprint: Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration. medRxiv. https://doi.org/10.1101/2020.04.29.20082099

Staines, Henry, Kirwan, Daniela, Clark, David, Adams, Emily, Augustin, Yolanda, Byrne, Rachel, Cocozza, Michael, Cubas-Atienzar, Ana, Cuevas, Luis, Cusinato, Martina, Davies, Benedict, Davis, Mark, Davis, Paul, Duvoix, Annelyse, Eckersley, Nicholas, Forton, Daniel, Fraser, Alice, Garrod, Gala, Hadcocks, Linda, Hu, Qinxue, Johnson, Michael, Kay, Grant, Klekotko, Kesja, Lewis, Zawditu, Macallan, Derek, Mensah-Kane, Josephine, Menzies, Stefanie, Monahan, Irene, Moore, Catherine, Nebe-von-Caron, Gerhard, Owen, Sophie, Sainter, Chris, Sall, Amadou, Schouten, James, Williams, Chris, Wilkins, John, Woolston, Kevin, Fitchett, Joseph, Krishna, Sanjeev and Planche, Tim 2020. Preprint: Dynamics of IgG seroconversion and pathophysiology of COVID-19 infections. medRxiv. https://doi.org/10.1101/2020.06.07.20124636

Catherine Margaret Moore, Melanie Grandits, Clemens Grünwald-Gruber, Friedrich Altmann, Maria Kotouckova, Audrey Y.H. Teh and Julian K.C. Ma 2020. Preprint: Characterisation of a Highly Potent and Near Pan-Neutralising Anti-HIV Monoclonal Antibody Expressed in Tobacco Plants. Research Square. https://doi.org/10.21203/rs.3.rs-104508/v1

Chan, S. 2020. Method Development and Validation for Establishing a Virtual HPLC Simulator (PharmAlliance Project).

Chan, S., Khatib, Y., Webley, S., Layton, D. and Salek, S. 2020. Identification of Cardiotoxicity related to Cancer Treatments: A Systematic Review. National Institute for Health and Care Research.

Lewis R. Mattin, Victoria J. McIver, Adora Mo Wah Yau, Lewis J. James and Gethin H. Evans 2020. A Comparison of Intermittent and Continuous Exercise Bouts at Different Intensities on Appetite and Postprandial Metabolic Responses in Healthy Men. Nutrients. 12 (8) 2370. https://doi.org/10.3390/nu12082370

Partridge, F.A., Forman, R., Bataille, C.J.R., Wynne, G.M., Nick, M., Russell, A.J., Else, K.J. and Sattelle, D.B. 2020. Anthelmintic drug discovery: target identification, screening methods and the role of open science. Beilstein Journal of Organic Chemistry. 16, pp. 1203-1224. https://doi.org/10.3762/bjoc.16.105

Brayson, D., Ehler, E., dos Remedios, C.G. and Shanahan, C.M. 2020. Preprint: Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape. medRxiv. https://doi.org/10.1101/2020.08.14.20168310

Brayson, D., Holohan, S-J., Bardswell, S.C., Arno, M., Lu, H., Jensen, H.K., Tran, P.K., Barallobre‐Barreiro, J., Mayr, M., dos Remedios, C.G., Tsang, V.T., Frigiola, A. and Kentish, J.C. 2020. Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association. 9 (16) e015342. https://doi.org/10.1161/jaha.119.015342

Piccus, R. and Brayson, D. 2020. The nuclear envelope: LINCing tissue mechanics to genome regulation in cardiac and skeletal muscle. Biology Letters. 16 (7) 20200302. https://doi.org/10.1098/rsbl.2020.0302

Srey, M.T., Taccogna, A., Oksov, Y., Lustigman, S., Tai, P-Y., Acord, J., Selkirk, M.E., Lamb, T.J. and Guiliano, D.B. 2020. Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection. PLoS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0008842

Hoffmann, R.M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H., Marlow, R., McDonnell, J.M., Figini, M., Lacy, K.E., Tutt, A.J.N., Spicer, J.F., Thurston, D.E., Karagiannis, S.N. and Crescioli, S. 2020. Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug conjugates (ADcs). Scientific Reports. 10 (1), pp. 1-11. https://doi.org/10.1038/s41598-020-65860-x

Rhéure Alves-Lopes, Karla B. Neves, Aikaterini Anagnostopoulou, Francisco J. Rios, Silvia Lacchini, Augusto C. Montezano and Rhian M. Touyz 2020. Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel. Hypertension. 75, pp. 139-149. https://doi.org/10.1161/hypertensionaha.119.13861

Aikaterini Anagnostopoulou, Livia de Lucca Camargo, Daniel Rodrigues, Augusto C. Montezano and Rhian Touyz 2020. Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells. Scientific Reports. 10 17818. https://doi.org/10.1038/s41598-020-73751-4

Alejandra B. Goya, Sophie Tarnovius, Robert G. Hatfield, Lewis Coates, Adam M. Lewis, Andrew D. Turner and Lewis, A. 2020. Paralytic shellfish toxins and associated toxin profiles in bivalve mollusc shellfish from Argentina. Harmful Algae. 99 101910. https://doi.org/10.1016/j.hal.2020.101910

Safi, A. 2020. Blog: Making the most of Ramadan during the COVID-19 pandemic. Birmingham City University.

Grau, I., Sengupta, D., Garcia Lorenzo, M.M. and Nowe, A. 2020. An interpretable semi-supervised classifier using rough sets for amended self-labeling. IEEE International Conference on Fuzzy Systems (FUZZ-IEEE 2020). Glasgow, UK 19 - 24 Jul 2020 IEEE . https://doi.org/10.1109/fuzz48607.2020.9177549

Porakishvili, N. and Lydyard, P. 2020. Cells, Tissues and Organs of the Immune System. in: Male, D., Peebles, S. and Male, V. (ed.) Immunology (9th edition) Elsevier. pp. 14-44

Hodges, C., Archer, F., Chowdhury, M., Evans, B.L., Ghelani, D.J., Mortoglou, M. and Guppy, F.M. 2020. Method of Food Preparation Influences Blood Glucose Response to a High-Carbohydrate Meal: A Randomised Cross-over Trial. Foods. 9 (1) 23. https://doi.org/10.3390/foods9010023

Mortoglou, M., Arisan, D., Ferreira, T., McCormick, A.L. and Uysal Onganer, P. 2020. Elevated microRNA expression could be diagnostic biomarker for PDAC. Pancreatology. 20 (8) e19. https://doi.org/10.1016/j.pan.2020.10.015

Rui Zhang, Monica Varela, Gabriel Forn-Cuní, Vincenzo Torraca, Michiel van der Vaart and Annemarie H. Meijer 2020. Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death and Disease. 11 277. https://doi.org/10.1038/s41419-020-2477-1

Vincenzo Torraca, Kathryn Holt and Serge Mostowy 2020. Shigella sonnei. Trends in Microbiology. 28 (8), pp. P696-697. https://doi.org/10.1016/j.tim.2020.02.011

Sommer, Frida, Torraca, V., Kamel, Sarah M., Lombardi, Amber and Meijer, Annemarie H. 2020. Frontline Science: Antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish. Journal of Leukocyte Biology. 107 (2), pp. 185-203. https://doi.org/10.1002/jlb.2hi0119-006r

Sommer, Frida, Torraca, V. and Meijer, Annemarie H. 2020. Chemokine Receptors and Phagocyte Biology in Zebrafish. Frontiers in Immunology. 11 325. https://doi.org/10.3389/fimmu.2020.00325

Frida Sommer, Torraca, V. and Annemarie H. Meijer 2020. Supplementary RNAseq dataset files. Zenodo. https://doi.org/10.5281/zenodo.3833847

David R. Stirling, Oniz Suleyman, Eliza Gil, Philip M. Elks, Vincenzo Torraca, Mahdad Noursadeghi and Gillian S. Tomlinson 2020. Analysis tools to quantify dissemination of pathology in zebrafish larvae. Scientific Reports. 10 3149. https://doi.org/10.1038/s41598-020-59932-1

Håkon Høgset, Conor C. Horgan, James P. K. Armstrong, Mads S. Bergholt, Vincenzo Torraca, Qu Chen, Timothy J. Keane, Laurence Bugeon, Margaret J. Dallman, Serge Mostowy and Molly M. Stevens 2020. In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy. Nature Communications . 11 6172. https://doi.org/10.1038/s41467-020-19827-1

Keith, R. 2020. Free school meals: the lifelong impact of childhood food poverty. theconversation.com.

Sum, K., Beckingham, S., Faulkner, S. and Baff, D. 2020. An interactive social media workshop using Lego® Serious Play®. Journal of Social Media for Learning. 1 (1), pp. 94-111. https://doi.org/10.24377/LJMU.jsml.vol1article392

Sum, K. 2020. Trust me, working alone is challenging: What are the benefits of working in partnership in higher education? in: Low, T. and El Hakim, Y. (ed.) A Handbook for Student Engagement in Higher Education: Theory into Practice Routledge.

Hosszu LLP, Conners R, Sangar D, Batchelor M, Sawyer EB, Fisher S, Cliff MJ, Hounslow AM, McAuley K, Leo Brady R, Jackson GS, Bieschke J, Waltho JP and Collinge J 2020. Structural effects of the highly protective V127 polymorphism on human prion protein. Communications Biology. 3 402. https://doi.org/10.1038/s42003-020-01126-6

Cadel-Six, Sabrina, Vignaud, Marie-Leone and Mohammed, Manal 2020. Erratum for Cadel-Six et al., “Draft Genome Sequences of Salmonella enterica subsp. enterica Serovar Dublin Strains from Raw Milk Cheeses Characterized by Multilocus Variable-Number Tandem-Repeat Analysis Profiles Associated with Two Outbreaks in France”. Microbiology Resource Announcements. 9 (7). https://doi.org/10.1128/mra.01590-19

Hatami Fard, G. 2020. Preparation of polysaccharide-based nanoemulsions to reduce melanoma drug resistance and inflammation markers. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/v4925

Schoop, R. 2020. Exploring In Vitro and In Vivo Pharmacology of Echinacea Purpurea (L.) Moench. PhD thesis University of Westminster Life Sciences https://doi.org/10.34737/v402v

Kyazze, G. 2020. Four ways microbial fuel cells might revolutionise electricity production in the future. The Conversation.