Life Sciences

CollegeLiberal Arts and Sciences
HeadProf Alistair Mathie
DeputyDr Ian Locke
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Book review: Toxic and Harmful Microalgae of the World Ocean, Patrick Lassus, Nicolas Chomérat, Philip Hess, Elizabeth Nézan. International Society for the Study of Harmful Algae/Intergovernmental Oceanographic Commission of UNESCO, Denmark (2016). IOC manuals and Guides 68. (Bilingual English/French)

Book review

Lewis, J. 2017. Book review: Toxic and Harmful Microalgae of the World Ocean, Patrick Lassus, Nicolas Chomérat, Philip Hess, Elizabeth Nézan. International Society for the Study of Harmful Algae/Intergovernmental Oceanographic Commission of UNESCO, Denmark (2016). IOC manuals and Guides 68. (Bilingual English/French). Harmful Algae. 63, p. 203. https://doi.org/10.1016/j.hal.2016.11.017

Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors

Journal article

Peiris, D., Spector, A.F., Lomax-Browne, H., Azimi, T., Ramesh, B., Loizidou, M., Welch, H. and Dwek, M. 2017. Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors. Scientific Reports. 7 43006. https://doi.org/10.1038/srep43006

Genome instability in childhood obesity: A conceptual framework for an assessment, intervention and monitoring programme of inflammation and DNA damage in paediatric obesity

Journal article

Usman, M., Tewfik, I. and Volpi, E. 2017. Genome instability in childhood obesity: A conceptual framework for an assessment, intervention and monitoring programme of inflammation and DNA damage in paediatric obesity. International Journal of Food, Nutrition and Public Health. 9 (1), pp. 1-12.

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations

Article

Rivollat, M., Rottier, S., Couture, C., Pemonge, M.H., Mendisco, F., Thomas, M.G., Deguilloux, M.F. and Gerbault, P. 2017. Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations. European Journal of Human Genetics. 25, pp. 388-392. https://doi.org/10.1038/ejhg.2016.180

Treatment of phenanthrene and benzene using microbial fuel cells operated continuously for possible in situ and ex situ applications

Article

Adelaja, O., Keshavarz, T. and Kyazze, G. 2017. Treatment of phenanthrene and benzene using microbial fuel cells operated continuously for possible in situ and ex situ applications. International Biodeterioration & Biodegradation. 116, p. 91–103. https://doi.org/10.1016/j.ibiod.2016.10.021

Formamide-free Fluorescence in situ Hybridization (FISH)

Book chapter

Volpi, E. 2017. Formamide-free Fluorescence in situ Hybridization (FISH). in: Liehr, T. (ed.) Fluorescence in situ Hybridization (FISH) - Application Guide Berlin Springer.

Decolourisation of Acid orange 7 in a microbial fuel cell with a laccase-based biocathode: Influence of mitigating pH changes in the cathode chamber

Article

Mani, P., Keshavarz, T., Chandra, T.S. and Kyazze, G. 2017. Decolourisation of Acid orange 7 in a microbial fuel cell with a laccase-based biocathode: Influence of mitigating pH changes in the cathode chamber. Enzyme and Microbial Technology. 96, pp. 170-176. https://doi.org/10.1016/j.enzmictec.2016.10.012

Clinical potential of oligonucleotide-based therapeutics in the respiratory system

Article

Moschos, S.A., Usher, L. and Lindsay, M.A. 2017. Clinical potential of oligonucleotide-based therapeutics in the respiratory system. Pharmacology and Therapeutics. 169, pp. 83-103. https://doi.org/10.1016/j.pharmthera.2016.10.009

A Prospective Randomized Controlled Trial to Study the Impact of a Nutrition-Sensitive Intervention on Adult Women With Cancer Cachexia Undergoing Palliative Care in India

Journal article

Kapoor, N., Naufahu, J., Tewfik, S., Bhatnagar, S., Garg, R. and Tewfik, I. 2017. A Prospective Randomized Controlled Trial to Study the Impact of a Nutrition-Sensitive Intervention on Adult Women With Cancer Cachexia Undergoing Palliative Care in India. Integrative Cancer Therapies. 6 (1), pp. 74-84. https://doi.org/10.1177/1534735416651968

Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPAreceptors

Journal article

Luchkina, N.V., Coleman, S.K., Huupponen, J., Cai, C., Kivisto, A., Taira, T., Keinanen, K. and Lauri, S.E. 2017. Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPAreceptors. Neuropharmacology. 112 (Part A), pp. 46-56. https://doi.org/10.1016/j.neuropharm.2016.04.049

Sustainable Chemical Regulation in a Global Environment

Book chapter

McEldowney, S. 2017. Sustainable Chemical Regulation in a Global Environment. in: Tan, C. and Faundez, J. (ed.) Natural Resources and Sustainable Development: International Economic Law Perspectives. Cheltenham Edward Elgar. pp. 257-276

Effects of the selective MC3 agonists PG990 and PG992 on Interleukin 1beta induced chondrocyte death and inflammation

Conference poster

Can, V.C., Locke, I.C., Grieco P and Getting, S.J. 2016. Effects of the selective MC3 agonists PG990 and PG992 on Interleukin 1beta induced chondrocyte death and inflammation. British Pharmacological Society: Pharmacology 2016. London 13 - 15 Dec 2016 British Pharmacological Society.

Tuning core hydrophobicity of spherical polymeric nanoconstructs for docetaxel delivery

Journal article

Daniele Di Mascolo, Pooja Basnett, Anna Lisa Palange, Marco Francardi, Ipsita Roy and Paolo Decuzzi 2016. Tuning core hydrophobicity of spherical polymeric nanoconstructs for docetaxel delivery. Polymer International. 65 (7), pp. 741-746. https://doi.org/10.1002/pi.5072

Making Nonwoven Fibrous Poly(ε-caprolactone) Constructs for Antimicrobial and Tissue Engineering Applications by Pressurized Melt Gyration

Journal article

Zewen Xu, Sunthar Mahalingam, Pooja Basnett, Bahijja Raimi-Abraham, Ipsita Roy and Duncan Craig 2016. Making Nonwoven Fibrous Poly(ε-caprolactone) Constructs for Antimicrobial and Tissue Engineering Applications by Pressurized Melt Gyration. Macromolecular Materials and Engineering. 301 (8), pp. 922-934. https://doi.org/10.1002/mame.201600116

Nanofibrous poly(3-hydroxybutyrate)/poly(3-hydroxyoctanoate) scaffolds provide a functional microenvironment for cartilage repair

Journal article

Ching, K.Y., Andriotis, O.G., Li, S., Basnett, P., Su, B., Roy, I., Tare, R.S., Sengers, B.G. and Stolz, M. 2016. Nanofibrous poly(3-hydroxybutyrate)/poly(3-hydroxyoctanoate) scaffolds provide a functional microenvironment for cartilage repair. Journal of Biomaterials Applications. 31 (1), pp. 77-91. https://doi.org/10.1177/0885328216639749

Benzocyclohexane oxide derivatives and neolignans from: Piper betle inhibit efflux-related resistance in Staphylococcus aureus

Journal article

Sun, Z.-L., He, J.-M., Wang, S.-Y., Ma, R., Khondkar, P., Kaatz, G.W., Gibbons, S. and Mu, Q. 2016. Benzocyclohexane oxide derivatives and neolignans from: Piper betle inhibit efflux-related resistance in Staphylococcus aureus. RSC Advances. 49. https://doi.org/10.1039/c6ra10199b

Non-human tools for the evaluation of bitter taste in the design and development of medicines: A systematic review

Journal article

Mohamed-Ahmed, A.H.A., Soto, J., Ernest, T. and Tuleu, C. 2016. Non-human tools for the evaluation of bitter taste in the design and development of medicines: A systematic review. Drug Discovery Today. 21 (7), pp. 1170-1180. https://doi.org/10.1016/j.drudis.2016.05.014

Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions

Journal article

Anna Keravnou, Marios Ioannides, Kyriakos Tsangaras, Charalambos Loizides, Michael D. Hadjidaniel, Elisavet a. Papageorgiou, Skevi Kyriakou, Pavlos Antoniou, Petros Mina, Achilleas Achilleos, Maria Neofytou, Elena Kypri, Carolina Sismani, George koumbaris and Philippos C. Patsalis 2016. Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions. Genetics Research. 98 e15. https://doi.org/10.1017/S0016672316000136

Cell-free DNA analysis of targeted genomic regions in maternal plasma for non-invasive prenatal testing of trisomy 21, trisomy 18, trisomy 13, and fetal sex

Journal article

George Koumbaris, Elena Kypri, Kyriakos Tsangaras, Achilleas Achilleos, Petros Mina, Maria Neofytou, Voula Velissariou, Georgia Christopoulou, Ioannis Kallikas, Alicia González-Liñán, Egle Benusiene, Anna Latos-Bielenska, Pietryga Marek, Alfredo Santana, Nikoletta Nagy, Márta Széll, Piotr Laudanski, Elisavet A. Papageorgiou, Marios Ioannides and Philippos C. Patsalis 2016. Cell-free DNA analysis of targeted genomic regions in maternal plasma for non-invasive prenatal testing of trisomy 21, trisomy 18, trisomy 13, and fetal sex. Clinical Chemistry. 62 (6), pp. 848-855. https://doi.org/10.1373/clinchem.2015.252502

The Welfare Effects of Trade in Phytomedicines: A Multi-Disciplinary Analysis of Turmeric Production

Journal article

Booker, A., Johnston, D. and Heinrich, M. 2016. The Welfare Effects of Trade in Phytomedicines: A Multi-Disciplinary Analysis of Turmeric Production. World Development. 77, pp. 221-230. https://doi.org/10.1016/j.worlddev.2015.08.024

The authenticity and quality of Rhodiola rosea products

Journal article

Booker, A., Jalil, B., Frommenwiler, D., Reich, E., Zhai, L., Kulic, Z. and Heinrich, M. 2016. The authenticity and quality of Rhodiola rosea products. Phytomedicine. 23 (7), pp. 754-762. https://doi.org/10.1016/j.phymed.2015.10.006

Treasures of pharmacognosy: 2nd Forum on Pharmaceutical History in Switzerland,Kostbarkeiten der pharmakognosie

Article

Anagnostou, S., Booker, A. and Ledermann, F. 2016. Treasures of pharmacognosy: 2nd Forum on Pharmaceutical History in Switzerland,Kostbarkeiten der pharmakognosie. Deutsche Apotheker Zeitung. 156 (51).

Genotoxic potential of chemotherapeutic agents in an in-vitro bystander model

Article

Okeke, K., Conway, M. and Morse, R. 2016. Genotoxic potential of chemotherapeutic agents in an in-vitro bystander model. Mutagenesis. 31 (6), pp. 726-727. https://doi.org/10.1093/mutage/gew044

Is elite sport a driver for medical advance? ; Ar didelio meistriškumo sportas skatina medicinos pažangą?

Journal article

Noble, Brendon 2016. Is elite sport a driver for medical advance? ; Ar didelio meistriškumo sportas skatina medicinos pažangą? Sport Science. 1 (86), pp. 2-7. https://doi.org/10.15823/sm.2016.1

Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan Endemic Nephropathy, is a regulator of K2P channels

Journal article

Veale, E.L. and Mathie, A. 2016. Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan Endemic Nephropathy, is a regulator of K2P channels. British Journal of Pharmacology. 173 (10), pp. 1639-1652. https://doi.org/10.1111/bph.13465

Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development

Journal article

Saia, M. and Barbieri, E. 2016. Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development. Oncotarget . 7, pp. 55302-55312 27486814. https://doi.org/10.18632/oncotarget.10878

AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells

Journal article

Saia, M., Termanini, A., Rizzi, N., Mazza, M., Barbieri, E., Valli, D., Ciana, P., Gruszka, A.M. and Alcalay, M. 2016. AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells. Scientific Reports. 6 34957. https://doi.org/10.1038/srep34957

Fad Diets: Lifestyle Promises and Health Challenges

Journal article

Khawandanah, Jomana and Tewfik, Ihab 2016. Fad Diets: Lifestyle Promises and Health Challenges. Journal of Food Research. 5 (6), pp. 80-94. https://doi.org/10.5539/jfr.v5n6p80

Palliative Nutritional Care for Cancer Patients

Journal article

Kapoor, Neha, Garg, Rakesh and Tewfik, Ihab 2016. Palliative Nutritional Care for Cancer Patients. Palliative Medicine and Hospice Care. 1 (3), pp. e1-e6. https://doi.org/10.17140/PMHCOJ1-e002

Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber

Journal article

Nazila Jafari, Sarah A. Kuehne, Nigel P. Minton, Elaine Allan and Mona Bajaj-Elliott 2016. Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber. Anaerobe. https://doi.org/10.1016/j.anaerobe.2015.12.007

Investigating the lipodystrophy genetic score associations with insulin sensitivity, ectopic and visceral fat in people at risk or with diabetes: a DIRECT study

Article

Frau, F., Mari, A., Thomas, E. L., Alenaini, W., Ruetten, H., 't Hart, L., Franks, P. W., Allebrandt, K. V., Bell, J. D. and Pearson, E. 2016. Investigating the lipodystrophy genetic score associations with insulin sensitivity, ectopic and visceral fat in people at risk or with diabetes: a DIRECT study. Diabetologia. 59 (Supplement 1), p. S175 Meeting Abstract 354.

Advanced Personal Training: science to practice

Book

Hough, P. and Penn, S. (ed.) 2016. Advanced Personal Training: science to practice. Routledge.

Intense human-animal interaction and limited capacity for the surveillance of zoonoses as drivers for Hepatitis E virus infections among animals and humans in Lao PDR

Journal article

Pauly, M., Muller, C.P., Black, A.P. and Snoeck, C.J. 2016. Intense human-animal interaction and limited capacity for the surveillance of zoonoses as drivers for Hepatitis E virus infections among animals and humans in Lao PDR. International Journal of Infectious Diseases. 53 (Supplement), p. p18. https://doi.org/10.1016/j.ijid.2016.11.051

Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria

Journal article

Adedoyin Dosunmu, Akinsegun Akinbami, Ebele Uche, Adewumi Adediran and Sarah John-Olabode 2016. Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria. Journal of Tropical Medicine. Volume 2016 4214387. https://doi.org/10.1155/2016/4214387

Impact of HIV infection and zidovudine therapy on RBC parameters and urine methylmalonic acid levels

Journal article

Adediran, A., Osunkalu, V., Wakama, T., John-Olabode, S., Akinbami, A., Uche, E. and Akanmu, S. 2016. Impact of HIV infection and zidovudine therapy on RBC parameters and urine methylmalonic acid levels. Interdisciplinary Perspectives on Infectious Diseases. Volume 2016 5210963. https://doi.org/10.1155/2016/5210963

Correction: Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial.

Article

Sutherland, K.A., Parry, C.M., McCormick, A.L., Kapaata, A., Lyagoba, F., Kaleebu, P., Gilks, C.F., Goodall, R., Spyer, M., Kityo, C., Pillay, D., Gupta, R.K. and DART Virology Group 2016. Correction: Evidence for Reduced Drug Susceptibility without Emergence of Major Protease Mutations following Protease Inhibitor Monotherapy Failure in the SARA Trial. PLoS ONE. 11 (6) e0157094. https://doi.org/10.1371/journal.pone.0157094

New paradigms in clonal evolution: punctuated equilibrium in cancer

Journal article

Cross, W., Graham, T.M. and Wright, N.A. 2016. New paradigms in clonal evolution: punctuated equilibrium in cancer. The Journal of Pathology. 240 (2), pp. 126-136. https://doi.org/10.1002/path.4757

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy

Journal article

Findlay, J.M., Castro-Giner, F., Makino, S., Rayner, E., Kartsonaki, C., Cross, W., Kovac, M., Ulahannan, D., Palles, C., Gillies, R.S., MacGregor, T.P. and Church, D. 2016. Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy. Nature Communications . 7 11111. https://doi.org/10.1038/ncomms11111

The Serotonin Transporter Promotes a Pathological Estrogen Metabolic Pathway in Pulmonary Hypertension via Cytochrome P450 1B1

Journal article

Anne Katrine Z. Johansen, Afshan Dean, Ian Morecroft, Katie Hood, Margaret Nilsen, Lynn Loughlin, Aikaterini Anagnostopoulou, Rhian M. Touyz, Kevin White and Margaret R. MacLean 2016. The Serotonin Transporter Promotes a Pathological Estrogen Metabolic Pathway in Pulmonary Hypertension via Cytochrome P450 1B1. Pulmonary Circulation. 6 (1), pp. 82-92. https://doi.org/10.1086/685023

Adipocyte-Specific Mineralocorticoid Receptor Overexpression in Mice Is Associated With Metabolic Syndrome and Vascular Dysfunction: Role of Redox-Sensitive PKG-1 and Rho Kinase

Journal article

Aurelie Nguyen Dinh Cat, Tayze T. Antunes, Glaucia E. Callera, Ana Sanchez, Sofia Tsiropoulou, Maria G. Dulak-Lis, Aikaterini Anagnostopoulou, Ying He, Augusto C. Montezano, Frederic Jaisser and Rhian M. Touyz 2016. Adipocyte-Specific Mineralocorticoid Receptor Overexpression in Mice Is Associated With Metabolic Syndrome and Vascular Dysfunction: Role of Redox-Sensitive PKG-1 and Rho Kinase. Diabetes. 65 (8), pp. 2392-2403. https://doi.org/10.2337/db15-1627


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