Life Sciences

Hurst, R.J., Hopwood, T., Gallagher, A.L., Partridge, F.A., Burgis, T., Sattelle, D.B. and Else, K.J. 2014. An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro. BMC Infectious Diseases. https://doi.org/10.1186/1471-2334-14-520

Hudson, L.E., Fasken, M.B., McDermott, C.D., McBride, S.M., Kuiper, E.G., Guiliano, D.B., Corbett, A.H. and Lamb, T.J. 2014. Functional Heterologous Protein Expression by Genetically Engineered Probiotic Yeast Saccharomyces boulardii. PLoS ONE. 9 (11) e112660. https://doi.org/10.1371/journal.pone.0112660

Guiliano, D.B., Fussell, H., Lenart, I., Tsao, E., Nesbeth, D., Fletcher, A.J., Campbell, E.C., Yousaf, N., Williams, S., Santos, S., Cameron, A., Towers, G.J., Kellam, P., Hebert, D.N., Gould, K.G., Powis, S.J. and Antoniou, A.N. 2014. Endoplasmic Reticulum Degradation-Enhancing α-Mannosidase-like Protein 1 Targets Misfolded HLA-B27 Dimers for Endoplasmic Reticulum-Associated Degradation. Arthritis & Rheumatology. 66 (11), pp. 2915-3250. https://doi.org/10.1002/art.38809

Anagnostopoulou, A., Hans-Peter Marti, James C. Fuscoe, Joshua C. Kwekel and Andreas Scherer 2014. Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species. Nephrology Dialysis Transplantation. 29 (6), p. 1177–1185. https://doi.org/10.1093/ndt/gfu027

Bandopadhyay, R., Liu, J.Y.W., Sisodiya, S.M. and Thom, M. 2014. A comparative study of the dentate gyrus in hippocampal sclerosis in epilepsy and dementia. Neuropathology and Applied Neurobiology. 40 (2), pp. 177-190. https://doi.org/10.1111/nan.12087

Liu, J.Y.W., Ellis, M., Brooke-Ball, H., de Tisi, J., Eriksson, S.H., Brandner, S., Sisodiya, S.M. and Thom, M. 2014. High-throughput, automated quantification of white matter neurons in mild malformation of cortical development in epilepsy. Acta Neuropathologica Communications. 2 72. https://doi.org/10.1186/2051-5960-2-72

Liu, J.Y.W., Reeves, C., Michalak, Z., Coppola, A., Diehl, B., Sisodiya, S.M. and Thom, M. 2014. Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies. Acta Neuropathologica Communications. 2 71. https://doi.org/10.1186/2051-5960-2-71

Bauer, M., Karch, R., Zeitlinger, M., Liu, J.Y.W., Koepp, M.J., Asselin, M.-C., Sisodiya, S.M., Hainfellner, J.A., Wadsak, W., Mitterhauser, M., Müller, M., Pataraia, E. and Langer, O. 2014. In vivo P-glycoprotein function before and after epilepsy surgery. Neurology. 83 (15). https://doi.org/10.1212/wnl.0000000000000858

Thom, M., Kensche, M., Maynard, J., Liu, J.Y.W., Reeves, C., Goc, J., Marsdon, D., Fluegel, D. and Foong, J. 2014. Interictal psychosis following temporal lobe surgery: dentate gyrus pathology. Psychological Medicine. 44 (14), pp. 3037-3049. https://doi.org/10.1017/s0033291714000452

Goc, J., Liu, J.Y.W., Sisodiya, S.M. and Thom, M. 2014. A spatiotemporal study of gliosis in relation to depth electrode tracks in drug-resistant epilepsy. European Journal of Neuroscience. 39 (12), pp. 2151-2162. https://doi.org/10.1111/ejn.12548

Battaglini, M., Rossi, F., Grove, R.A., Stromillo, M.L., Whitcher, B., Matthews, P.M. and De Stefano, N. 2014. Automated identification of brain new lesions in multiple sclerosis using subtraction images. Journal of Magnetic Resonance Imaging. 39 (6), pp. 1543-1549. https://doi.org/10.1002/jmri.24293

De Clerck, Q., Nowe, A., Coletta, A. and Sengupta, D. 2014. Benchmarking pre-processing and batch effect removal methods for Insilico DB: Genomics Big Data Infrastructure. 9th Benelux Bioinformatics Conference (BBC 2014). Novotel-Kirchberg, Luxembourg 08 - 09 Dec 2014

Atri, P., Sengupta, D., Verma, S., Ali, S. and Dey, G. 2014. Homology Modeling of Bacteriocins: From sequence alignments to structural models. International Journal of Scientific & Engineering Research. 5 (5), pp. 123-126.

Thanki, A.S., Caim, S., Corpas, M. and Davey, R.P. 2014. DNAContentViewer a BioJS component to visualise GC/AT Content. F1000Research. 3 54. https://doi.org/10.12688/f1000research.3-54.v1

Thanki, A.S., Jimenez, R.C., Kaithakottil, G.G., Corpas, M. and Davey, R.P. 2014. wigExplorer, a BioJS component to visualise wig data. F1000Research. 3 53. https://doi.org/10.12688/f1000research.3-53.v1

Corpas, M., Jimenez, R., Carbon, S.J., GarcÍa, A., Garcia, L., Goldberg, T., Gomez, J., Kalderimis, A., Lewis, S.E., Mulvany, I., Pawlik, A., Rowland, F., Salazar, G., Schreiber, F., Sillitoe, I., Spooner, W.H., Thanki, A.S., Villaveces, J.M., Yachdav, G. and Hermjakob, H. 2014. BioJS: An open source standard for biological visualisation - its status in 2014. F1000Research. 3 55. https://doi.org/10.12688/f1000research.3-55.v1

Corpas, M. 2014. The BioJS article collection of open source components for biological data visualisation. F1000Research. 3 56. https://doi.org/10.12688/f1000research.3-56.v1

David L.V. Bauer, Rodolphe M. Marie, Jonas N. Pedersen, Kristian H. Rasmussen, Mohammed Yusuf, Emanuela Volpi, Henrik Flyvbjerg, Anders Kristensen and Kalim U. Mir 2014. Nanofluidics to Enhance Single Molecule DNA Imaging: Detecting Genomic Structural Variation in Humans. Biophysical Journal. 106 (2, supplement 1), p. 395A. https://doi.org/10.1016/j.bpj.2013.11.2229

Torraca, V., Masud, S., Spaink, H.P. and Meijer, A.H. 2014. Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model. Disease Models and Mechanisms. 7 (7), pp. 785-797. https://doi.org/10.1242/dmm.015594

Bell, P.G., Gaze, D.C., Davison, G.W., George, T.W., Scotter, M.J. and Howatson, G. 2014. Montmorency tart cherry (Prunus cerasus L.) concentrate lowers uric acid, independent of plasma cyanidin-3-O-glucosiderutinoside. Journal of Functional Foods. 11, pp. 82-90. https://doi.org/10.1016/j.jff.2014.09.004

Zhou, X.-M., Entwistle, A., Zhang, H., Jackson, A.P., Mason, T.O., Shimanovich, U., Knowles, T.P.J., Smith, A.T., Sawyer, E.B. and Perrett, S. 2014. Self-assembly of amyloid fibrils that display active enzymes. ChemCatChem. 6 (7), pp. 1961-1968. https://doi.org/10.1002/cctc.201402125

Hu, C., Chan, S.I., Sawyer, E.B., Yu, Y. and Wang, J. 2014. Metalloprotein design using genetic code expansion. Chemical Society Reviews. 43, pp. 6498-6510. https://doi.org/10.1039/c4cs00018h

Patel, H. and Kukol, A 2014. Influenza A nucleoprotein binding sites for antivirals: current research and future potential. Future Virology. 9, pp. 625-627. https://doi.org/10.2217/fvl.14.45

Li, J., Kent, D.G., Godfrey, A.L., Manning, H., Nangalia, J., Aziz, A., Chen, E., Saeb-Parsy, K., Find, J., Sneade, R., Hamilton, T.L., Pask, D.C., Silber, Y., Zhao, X., Ghevaert, C., Liu, P. and Green, A.R. 2014. JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease. Blood. 123, pp. 3139-3151. https://doi.org/10.1182/blood-2013-06-510222

Chen, E., Ahn, J.S., Massie, C.E., Clynes, D., Godfrey, A.L., Li, J., Park, H.J., Nangalia, J., Silber, Y., Mullally, A., Gibbons, R.J. and Green, A.R. 2014. JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response. Proceedings of the National Academy of Sciences of the United States of America. 111, pp. 15190-15195. https://doi.org/10.1073/pnas.1401873111

Chen, E. and Mullally, A. 2014. How does JAK2V617F contribute to pathogenesis of myeloproliferative neoplasms? (Review). Hematology American Society of Hematology Education Program. 2014, pp. 268-276. https://doi.org/10.1182/asheducation-2014.1.268

Phillips, G., Bottomley, C., Schmidt, E., Tobi, P., Lais, S., Yu, G., Lynch, R., Lock, K., Draper, A., Moore, D., Clow, A., Petticrew, M., Hayes, R. and Renton, A. 2014. Well London Phase-1: results among adults of a cluster-randomised trial of a community engagement approach to improving health behaviours and mental well-being in deprived inner-city neighbourhoods . Journal of Epidemiology & Community Health. 68 (7), pp. 606-614. https://doi.org/10.1136/jech-2013-202505

Taneja, A., Gaze, D.C., Coats, A., Dumitrascu, D., Spinarova, L., Collinson, P., Roughton, M. and Flather, M. 2014. Effects of nebivolol on biomarkers in elderly patients with heart failure. International Journal of Cardiology. 175 (2), pp. 253-260. https://doi.org/10.1016/j.ijcard.2014.05.018

Leeder, J., van Someren, K., Gaze, D.C., Jewell, A., Deshmukh, N., Shah, I., Barker, J. and Howatson, G. 2014. Recovery and Adaptation From Repeated Intermittent-Sprint Exercise. International Journal of Sports Physiology and Performance. 9 (3), pp. 489-946. https://doi.org/10.1123/ijspp.2012-0316

Gaze, D.C. and Collinson, P. 2014. Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. Open Heart. 1 (1), p. e000108 e000108. https://doi.org/10.1136/openhrt-2014-000108

Gaze, D.C., Prante, C., Dreier, J., Knabbe, C., Collet, C., Launay, J., Franekova, J., Jabor, A., Lennartz, L., Shih, J., del Rey, J., Zaninotto, M., Plebani, M. and Collinson, P. 2014. Analytical evaluation of the automated galectin-3 assay on the Abbott ARCHITECT immunoassay instruments. Clinical Chemistry and Laboratory Medicine . 52 (6), pp. 919-926. https://doi.org/10.1515/cclm-2013-0942

Gaze, D.C. 2014. Research Highlights: Run for your life: reduction in inflammatory mediators following cardiac rehabilitation. Biomarkers in Medicine. 8 (2), pp. 233-237. https://doi.org/10.2217/bmm.13.148

Collinson, P., Gaze, D.C. and Goodacre, S. 2014. Comparison of contemporary troponin assays with the novel biomarkers, heart fatty acid binding protein and copeptin, for the early confirmation or exclusion of myocardial infarction in patients presenting to the emergency department with chest pain. Heart. 100 (2), pp. 140-145. https://doi.org/10.1136/heartjnl-2013-304716

MacKenzie, R. and Elliott, B. 2014. Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 7, pp. 55-67. https://doi.org/10.2147/DMSO.S48260

Newell, M., Wallis, G.A. and Galloway, S.D.R. 2014. Impact of carbohydrate nutrition on exercise metabolism and performance. AgroFOOD Industry Hi-Tech. 25 (2), pp. 32-36.

Youssef, G., Gillett, C., Agbaje, O., Crompton, T. and Montano Hernandez, X. 2014. Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer. Modern Pathology. 27, pp. 361-374 23948750. https://doi.org/10.1038/modpathol.2013.129

Preston, L.J. and Dartnell, L. 2014. Planetary habitability: lessons learned from terrestrial analogues. International Journal of Astrobiology. 13 (1). https://doi.org/10.1017/S1473550413000396

Dartnell, L. and Patel, M.R. 2014. Degradation of microbial fluorescence biosignatures by solar ultraviolet radiation on Mars. International Journal of Astrobiology. 13 (2), pp. 112-123. https://doi.org/10.1017/S1473550413000335

Herschy, B., Whicher, A., Camprubi, E., Watson, C., Dartnell, L., Ward, J., Evans, J.R.G. and Lane, N. 2014. An Origin-of-Life Reactor to Simulate Alkaline Hydrothermal Vents. Journal of Molecular Evolution. 79 (5-6), pp. 213-227. https://doi.org/10.1007/s00239-014-9658-4

Makela, P., Gawned, S and Jones, F 2014. Starting early: integration of self-management support into an acute stroke service. BMJ Open Quality. 3 (1) u202037.w1759. https://doi.org/10.1136/bmjquality.u202037.w1759