Life Sciences

Nyga, A., Stamati, Katerina, Redondo, Patricia A, Azimi, Tayebeh, Feber, Andrew, Neves, Joana B, Hamoudi, Rifat, Presneau, Nadège, El Sheikh, Soha, Tran, Maxine G B, Emberton, Mark, Loizidou, Marilena and Cheema, Umber 2022. Renal tumouroids: challenges of manufacturing 3D cultures from patient derived primary cells. Journal of Cell Communication and Signaling. 16, pp. 637-648. https://doi.org/10.1007/s12079-022-00666-2

Tiekou Lorinczova, H., Begum, G., Temouri, L., Renshaw, D. and Zariwala, M. 2022. Co-Administration of Iron and Bioavailable Curcumin Reduces Levels of Systemic Markers of Inflammation and Oxidative Stress in a Placebo-Controlled Randomised Study. Nutrients. 14 (3) 712. https://doi.org/10.3390/nu14030712

Safi, A., Cole, M., Kelly, A., Deb, S. and Walker, N. 2022. A Comparison of Physical Activity and Sedentary Lifestyle of University Employees through ActiGraph and IPAQ-LF. Physical Activity and Health. 6 (1), pp. 5-15. https://doi.org/10.5334/paah.163

Hundal, S. and Green, Julia 2022. Experience of Western Herbal Medicine practitioners in supporting brain health in mid-life and older patients: a qualitative research study. Journal of Herbal Medicine. 32 100547. https://doi.org/10.1016/j.hermed.2022.100547

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2022. Thermodynamics and Inflammation: Insights into Quantum Biology and Ageing. Quantum Reports. 4, pp. 47-74. https://doi.org/10.3390/quantum4010005

Martin, S., Tyrrell, J., Thomas, E.L., Bown, M.J., Wood, A.R., Beaumont, R.N., Tsoi, L.C., Stuart, P.E., Elder, J.T., Law, P., Houlston, R., Kabrhel, C., Papadimitriou, N., Gunter, M.J., Bull, C.J., Bell, J.A., Vincent, E.E., Sattar, N., Dunlop, M.G., Tomlinson, I.P.M., Bell, J.D., Frayling, T. and Yaghootkar, H. 2022. Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation. eLife. 11 e72452. https://doi.org/10.7554/elife.72452

Mortoglou, M., Miralles, F., Arisan, E.D., Dart, A., Jurcevic, S., Lange, S. and Uysal Onganer, P. 2022. microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells. International Journal of Molecular Sciences. 23 (3) 1275. https://doi.org/10.3390/ijms23031275

Gaspar Quinonez, C., Lee, J.J., Lim, J., Odell, M., Lawson, C.P., Anyogu, A., Raheem, S. and Eoh, H. 2022. The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis. mBio. 13 (1), pp. e03559-21. https://doi.org/10.1128/mbio.03559-21

Wesolowska-Andersen, A., Brorsson, C.A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Viñuela, A., Fernandez Tajes, J, Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M-G, Musholt, P.B, Kurbasic, A., Masi, F., Tsirigos, K, Pedersen, H., Gudmundsdottir, V., Thomas, C., Banasik, K., Jennison, C., Jones, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Thomsen, H., Allin, K., Hansen, T.H., Vestergaard, H., Hansen, T., Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Giordano, G.N., Froguel, P., Pavo, I., Ruetten, H., Pedersen, O., Dermitzakis, E., Franks, P.W., Schwenk, J.M., Adamski, J., Pearson, E., McCarthy, M.I., Brunak, S. and IMI DIRECT Consortium 2022. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. Cell Reports Medicine. 3 (1) 100477. https://doi.org/10.1016/j.xcrm.2021.100477

Martin, Susan, Sorokin, Elena P, Thomas, E Louise, Sattar, Naveed, Cule, Madeleine, Bell, Jimmy D and Yaghootkar, H. 2022. Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study. Diabetes Care. 45 (2), pp. 460-468. https://doi.org/10.2337/dc21-1262

Wickstead, E. S., Irving, M. A., Getting, S. J. and McArthur, S. 2022. Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer's disease treatment. The FEBS Journal. 289 (7), pp. 1801-1822. https://doi.org/10.1111/febs.15861

Hassan Morad, Suaib Luqman, Chun-Hsiang Tan and Peter McNaughton 2021. TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide. Dynamic Cell IV. 14 - 19 Mar 2021 The Biochemical Society.

Nihaya A. Al-Sheyab, Mohannad Al Nsour, Yousef S. Khader, Hind Yousif, Mohammad S. Alyahya, Hana Taha, Marco Bardus, Malika Al Kattan and Mirwais Amiri 2021. Midwives and women's perspectives on family planning in Jordan: human rights, gender equity, decision-making and power dynamics. Heliyon. 7 (8) E07810. https://doi.org/10.1016/j.heliyon.2021.e07810

Hind Yousef, Nihaya Al-Sheyab, Mohannad Al Nsour, Yousef Khader, Malika Al Kattan, Marco Bardus, Mohammad Alyahya, Hana Taha and Mirwais Amiri 2021. Perceptions Toward the Use of Digital Technology for Enhancing Family Planning Services: Focus Group Discussion With Beneficiaries and Key Informative Interview With Midwives. Journal of Medical Internet Research. 23 (7) e25947. https://doi.org/10.2196/25947

Mathie, A. 2021. Heterologous Expression of Ion Channels in Mammalian Cell Lines. in: Dallas, M. and Bell, D. (ed.) Patch Clamp Electrophysiology: Methods and Protocols Springer. pp. 51-65

Stephen P.H. Alexander, Alistair Mathie, John A. Peters, Emma L. Veale, Jörg Striessnig, Eamonn Kelly, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, Martin Biel, Roslyn M. Bill, William A. Catterall, Alex C. Conner, Paul Davies, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Stefanie Fenske, Chandy George, Steve A.N. Goldstein, Stephan Grissmer, Kotdaji Ha, Verena Hammelmann, Israel Hanukoglu, Mike Jarvis, Anders A. Jensen, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Joseph W. Lynch, Edward Perez‐Reyes, Leigh D. Plant, Lachlan Rash, Dejian Ren, Mootaz M. Salman, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Joris Vriens, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Lixia Yue, Xiaoli Zhang and Michael Zhu 2021. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels. British Journal of Pharmacology. 178 (S1), pp. S157-S245. https://doi.org/10.1111/bph.15539

Stephen P.H. Alexander, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M.H. Anderson, Philip Mark Beart, Stefan Broer, Paul A. Dawson, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Gavin Stewart, David T. Thwaites and Tiziano Verri 2021. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. British Journal of Pharmacology. 178 (S1), pp. S412-S513. https://doi.org/10.1111/bph.15543

Stephen P.H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Kenneth E. Bernstein, Bernhard Bettler, Nigel J.M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Khuraijam Dhanachandra Singh, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Tom Lloyd Williams, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip Murphy, Jean‐Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter (Wally) Thomas, Pieter B.M.W.M. Timmermans, Kalyan Tirupula, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B Willars, Trent M. Woodruff, Chengcan Yao and Richard D. Ye 2021. The Concise Guide to Pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology. 178 (S1), pp. S27-S156. https://doi.org/10.1111/bph.15538

Stephen P H Alexander, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, O Peter Buneman, John A Cidlowski, Arthur Christopoulos, Anthony P Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jamie A Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang and Yalda Zolghadri 2021. The Concise Guide to Pharmacology 2021/22: Introduction and Other Protein Targets. British Journal of Pharmacology. 178 (S1), pp. S1-S26. https://doi.org/10.1111/bph.15537

Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Doris Koesling, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Michael Russwurm, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts and Szu Shen Wong 2021. The Concise Guide to Pharmacology 2021/22: Enzymes. British Journal of Pharmacology. 178 (S1), pp. S313-S411. https://doi.org/10.1111/bph.15542

Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, Jamie A. Davies, Annie Beuve, Peter Brouckaert, Clare Bryant, John C. Burnett, Richard W. Farndale, Andreas Friebe, John Garthwaite, Adrian J. Hobbs, Gavin E. Jarvis, Michaela Kuhn, David MacEwan, Tom P. Monie, Lincoln R. Potter, Harald H.H.W. Schmidt and Scott A. Waldman 2021. The Concise Guide to Pharmacology 2021/22: Catalytic receptors. British Journal of Pharmacology. 178 (S1), pp. S264-S312. https://doi.org/10.1111/bph.15541

Stephen P H Alexander, John A Cidlowski, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Laurel Coons, Peter J. Fuller, Kenneth S. Korach and Morag J. Young 2021. The Concise Guide to Pharmacology 2021/22: Nuclear hormone receptors. British Journal of Pharmacology. 178 (S1), pp. S246-S263. https://doi.org/10.1111/bph.15540

Mathie, A. 2021. Pharmacological Approaches to Studying Potassium Channels. in: Nikita Gamper and KeWei Wang (ed.) Pharmacology of Potassium Channels Springer. pp. 83-111

Yvonne Walsh, Michael Leach, Emma L. Veale and Alistair Mathie 2021. Block of TREK and TRESK K2P channels by lamotrigine and two derivatives sipatrigine and CEN-092. Biochemistry and Biophysics Reports. 26. https://doi.org/10.1016/j.bbrep.2021.101021

Mathie, A. 2021. A “Target Class” Screen to Identify Activators of Two-Pore Domain Potassium (K2P) Channels. SLAS DISCOVERY: Advancing the Science of Drug Discovery. 26 (3), pp. 428-438. https://doi.org/10.1177/2472555220976126

Antonio de Marvao, Kathryn A. McGurk, Sean L. Zheng, Marjola Thanaj, Wenjia Bai, Jinming Duan, Carlo Biffi, Francesco Mazzarotto, Ben Statton, Timothy J.W. Dawes, Nicolò Savioli, Brian P. Halliday, Xiao Xu, Rachel J. Buchan, A John Baksi, Marina Quinlan, Paweł Tokarczuk, Upasana Tayal, Catherine Francis, Nicola Whiffin, Pantazis I. Theotokis, Xiaolei Zhang, Mikyung Jang, Alaine Berry, Antonis Pantazis, Paul J.R. Barton, Daniel Rueckert, Sanjay K. Prasad, Roddy Walsh, Carolyn Y. Ho, Stuart A. Cook, James S. Ware and Declan P. O’Regan 2021. Preprint: Outcomes and phenotypic expression of rare variants in hypertrophic cardiomyopathy genes amongst UK Biobank participants. medRxiv. https://doi.org/10.1101/2021.01.21.21249470

Zubaidah, E., Nisak, Y.K., Susanti, I., Widyaningsih, T.D., Srianta, I. and Tewfik, I. 2021. Turmeric Kombucha as effective immunomodulator in Salmonella typhi-infected experimental animals. Biocatalysis and Agricultural Biotechnology. 37 102181. https://doi.org/10.1016/j.bcab.2021.102181

Adegboye A.R.A., Bawa, M., Keith, R., Tewfik, S. and Tewfik, I. 2021. Edible Insects: Sustainable nutrient-rich foods to tackle food insecurity and malnutrition. World Nutrition. 12 (4), pp. 176-189.

Dimitriou, C., Giachali, M., Lagogiannis, D., Anesti, M., Ghevaert, C., Franklin, R., Rivera, F. and Kazanis, I. 2021. Platelets' regulatory role on postnatal brain Neural Stem Cells of the Subependymal Zone. GLIA. 69 (S1), pp. E501-E502. https://doi.org/10.1002/glia.24036

Dimitrakopoulos, D., Kakogiannis, D., Franklin, R.J. and Kazanis, I. 2021. "Milking": an innovative approach to investigate the properties of postnatal brain neural stem cells and to obtain oligodendrocyte progenitor cells from live experimental rats. GLIA. 69 (S1), p. E411. https://doi.org/10.1002/glia.24036

Dimitriou, C., Papadimitriou, K., Roussis, K., Guerrero, J., Ghevaert, C., Franklin, R., Symeonidis, A. and Kazanis, I. 2021. Platelets as novel regulators of postnatal brain Neural Stem Cells. GLIA. 67 (S1), pp. E647-E648. https://doi.org/10.1002/glia.23675

Anesti, M., Magkafa, S., Prantikou, E. and Kazanis, I. 2021. Neurogenic and oligodendrogenic cell fate decisions of postnatal brain Neural Stem Cells are differentially dependent on their microenvironment. GLIA. 69 (S1), pp. E415-E416. https://doi.org/10.1002/glia.24036

Freyja McClenahan, Christina Dimitriou, Christos Koutsakis, Dimitrios Dimitrakopoulos, Asterios Arampatzis, Paraskevi Kakouri, Michaela Kourla, Sofia Oikonomou, Evangelia Andreopoulou, Melina Patsonis, Danai-Kassandra Meri, Rana-Tahir Rasool, Robin JM. Franklin and Ilias Kazanis 2021. Isolation of neural stem and oligodendrocyte progenitor cells from the brain of live rats. Stem Cell Reports. 16 (10), pp. 2534-2547. https://doi.org/10.1016/j.stemcr.2021.08.015

Theodora Mourtzi, Dimitrios Dimitrakopoulos, Dimitrios Kakogiannis, Charalampos Salodimitris, Konstantinos Botsakis, Danai Kassandra Meri, Maria Anesti, Aggeliki Dimopoulou, Ioannis Charalampopoulos, Achilleas Gravanis, Nikolaos Matsokis, Fevronia Angelatou and Ilias Kazanis 2021. Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20. Stem Cell Research & Therapy. 12 335. https://doi.org/10.1186/s13287-021-02398-3

Martin, Susan, Tyrrell, Jessica, Thomas, Elizabeth L., Bown, Matthew, Elder, James T., Kabrhel, Christopher, Papadimitriou, Nikos, Gunter, Marc, Vincent, Emma E., Bell, Jimmy D., Frayling, Timothy M. and Yaghootkar, Hanieh 2021. Using Genetics to Uncouple Higher Adiposity from Its Adverse Metabolic Effects. Diabetes. 70 (Supplement 1) 190-LB. https://doi.org/10.2337/db21-190-lb

Hough, P., Pedlar, C., North, J. and Patterson, S. 2021. Monitoring athletes sleep: a survey of current trends amongst practitioners. Journal of Sport & Exercise Science. 5 (4), pp. 277-284. https://doi.org/10.36905/jses.2021.04.06

Hough, P. and Schoenfeld, B. (ed.) 2021. Advanced Personal Training: Science to Practice (2nd ed.). Routledge.

Wooller, S., Anagnostopoulou, A., Kuropka, B., Crossley, M., Benjamin, P.R., Pearl, F., Kemenes, I., Kemenes, G. and Eravci, M. 2021. Preprint: A combined bioinformatics and LC-MS based approach for the development and benchmarking of a comprehensive database for CNS proteins in Lymnaea stagnalis. biorxiv.org. https://doi.org/10.1101/2021.05.03.442491

Hatakeyama, D., Sunada, H., Totani, Y., Watanabe, T., Felletár, I., Fitchett, A., Eravci, M., Anagnostopoulou, A., Miki, R., Kuzuhara, T., Kemenes, I., Ito, E. and Kemenes, G. 2021. Preprint: Histone acetyltransferase activity of CREB-binding protein is essential for synaptic plasticity in Lymnaea. biorxiv.org. https://doi.org/10.1101/2021.05.26.445902

Basty, Nicolas, Thanaj, Marjola, Cule, Madeleine, Sorokin, Elena, Liu, Yi, Bell, Jimmy D., Thomas, E. Louise and Whitcher, Brandon 2021. Preprint: Swap-Free Fat-Water Separation in Dixon MRI using Conditional Generative Adversarial Networks. arXiv. https://doi.org/10.48550/arXiv.2107.14175