Life Sciences

Yotam Levy, Jacob A. Ross, Marili Niglas, Vladimir A. Snetkov, Steven Lynham, Chen-Yu Liao, Megan J. Puckelwartz, Yueh-Mei Hsu, Elizabeth M. McNally, Manfred Alsheimer, Stephen D.R. Harridge, Stephen G. Young, Loren G. Fong, Yaiza Español, Carlos Lopez-Otin, Brian K. Kennedy, Dawn A. Lowe and Julien Ochala 2018. Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness. JCI Insight. 3 (19) e120920. https://doi.org/10.1172/jci.insight.120920

Danquah, C.A., Kakagianni, E., Khondkar, P., Maitra, A., Rahman, M., Evangelopoulos, D., McHugh, T.D., Stapleton, P., Malkinson, J., Bhakta, S. and Gibbons, S. 2018. Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition. Scientific Reports. 8. https://doi.org/10.1038/s41598-017-18948-w

Mohamed-Ahmed, A.H.A., Lockwood, A., Fadda, H., Madaan, S., Khaw, P.T., Brocchini, S. and Karu, K. 2018. LC–MS analysis to determine the biodistribution of a polymer coated ilomastat ocular implant. Journal of Pharmaceutical and Biomedical Analysis. 157, pp. 100-106. https://doi.org/10.1016/j.jpba.2018.05.017

Cheung, L.C., Nguyen, M., Tang, E., von Ungern Sternberg, B.S., Salman, S., Tuleu, C., Mohamed Ahmed, A.H.A., Soto, J. and Lim, L.Y. 2018. Taste evaluation of a novel midazolam tablet for pediatric patients: In vitro drug dissolution, in vivo animal taste aversion and clinical taste perception profiles. International Journal of Pharmaceutics. 535 (1-2), pp. 194-200. https://doi.org/10.1016/j.ijpharm.2017.10.060

Maria Neofytou, Nathalie Brison, Kris Van den Bogaert, Luc Dehaspe, Koen Devriendt, Anja Geerts and Joris R. Vermeesch 2018. Maternal liver transplant: Another cause of discordant fetal sex determination using cell-free DNA. Prenatal Diagnosis. 38 (2), pp. 148-150. https://doi.org/10.1002/pd.5194

Anna Keravnou, Marios Ioannides, Charalambos Loizides, Kyriakos Tsangaras, Achilleas Achilleos, Petros Mina, Elena Kypri, Michael D. Hadjidaniel, Maria Neofytou, Skevi Kyriacou, Carolina Sismani, George Koumbaris and Philippos C. Patsalis 2018. MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT. PLoS ONE. 13 (6) e0199010. https://doi.org/10.1371/journal.pone.0199010

Nathalie Brison, Maria Neofytou, Luc Dehaspe, Baran Bayindir, Kris Van Den Bogaert, Griet Van Buggenhout, Leila Dardour, Hilde Peeters, Hilde Van Esch, Annick Vogels, Thomy de Ravel, Eric Legius, Koen Devriendt and Joris R. Vermeesch 2018. Predicting fetoplacental chromosomal mosaicism during non-invasive prenatal testing. Prenatal Diagnosis. 38 (4), pp. 258-266. https://doi.org/10.1002/pd.5223

Curtis, C. 2018. Enhancing dietary practices, general nutrition knowledge and body composition of a female International Rugby Union player incorporating smartphone application technology. The Journal of Sports Medicine and Physical Fitness. 58 (3), pp. 366-8. https://doi.org/10.23736/s0022-4707.17.07623-x

Okeke, K., Conway, M. and Morse, R. 2018. Evidence of chemotherapy-induced bystander effect and a potential involvement of reactive oxygen species in an in vitro co-culture model. Mutagenesis. 33 (5-6), pp. 392-393. https://doi.org/10.1093/mutage/gey033

Alexandre J.C. Loucif, Pierre-Philippe Saintot, Jia Liu, Brett M. Antonio, Shannon G. Zellmer, Katrina Yoger, Emma L. Veale, Anna Wilbrey, Kiyoyuki Omoto, Lishuang Cao, Alex Gutteridge, Neil A. Castle, Edward B. Stevens and Alistair Mathie 2018. GI-530159, a novel, selective, mechano-sensitive K2P channel opener, reduces rat dorsal root ganglion (DRG) neuron excitability. British Journal of Pharmacology. 175 (12), pp. 2272-2283. https://doi.org/10.1111/bph.14098

Mondejar-Parreño, G., Morales-Cano, D., Barreira, B., Callejo, M., Ruiz-Cabello, J., Moreno, L., Esquivel-Ruiz, S., Mathie, A., Butrous, G., Perez-Vizcaino, F. and Cogolludo, A. 2018. HIV transgene expression impairs K+ channel function in the pulmonary vasculature. American Journal of Physiology: Lung and Molecular Physiology. 315 (5), pp. L711-L723. https://doi.org/10.1152/ajplung.00045.2018

Fernández-Fernández, D., Cadaveira-Mosquera, A., Rueda-Ruzafa, L., Herrera-Pérez, S., Veale, E.L., Reboreda, A., Mathie, A. and Lamas, J.A. 2018. Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons. PLoS ONE. 13 (6) e0199282. https://doi.org/10.1371/journal.pone.0199282

Emma L Veale, Adrian J Stewart, Alistair Mathie, Satvinder K Lall, Melanie Rees-Roberts, Vilius Savickas, Sukvinder K Bhamra and Sarah A Corlett 2018. Pharmacists detecting atrial fibrillation (PDAF) in primary care during the influenza vaccination season: a multisite, cross-sectional screening protocol. BMJ Open. 8 (3) e021121. https://doi.org/10.1136/bmjopen-2017-021121

Thanaj, M., Chipperfield, A.J. and Clough, G.F. 2018. Multiscale Analysis of Microvascular Blood Flow and Oxygenation. World Congress on Medical Physics and Biomedical Engineering 2018. Prague, Czech Republic 03 - 08 Jun 2018 Springer. https://doi.org/10.1007/978-981-10-9038-7_36

Thanaj, M., Chipperfield, A.J. and Clough, G.F. 2018. Analysis of microvascular blood flow and oxygenation: Discrimination between two haemodynamic steady states using nonlinear measures and multiscale analysis. Computers in Biology and Medicine. 102, pp. 157-167. https://doi.org/10.1016/j.compbiomed.2018.09.026

Al-Joufi, F., El-Bana, M., Tewfik, I. and Anwar, M. 2018. Efficacy of co-supplementation therapy with vitamins B9, B12, and D on endothelial dysfunction in streptozotocin-induced diabetic rats. Asian Journal of Pharmaceutical and Clinical Research . 11 (9), pp. 407-410. https://doi.org/10.22159/ajpcr.2018.v11i9.25361

Yaghootkar, Hanieh, Ji, Yingjie, Yiorkas, Andrianos M., Frau, Francesca, Mook-Kanamori, Dennis, De Mutsert, Renee, Tyrrell, Jessica, Jones, Samuel E., Beaumont, Robert, Wood, Andrew R., Thomas, Louise, Allebrandt, Karla V., Stefan, Norbert, Staiger, Harald, Pearson, Ewan, Blakemore, Alex I., Bell, Jimmy D. and Frayling, Timothy M. 2018. Genome-Wide and Abdominal Imaging Data Characterizes Common Alleles Associated with Higher BMI and Subcutaneous Fat but Less Liver Fat and Lower Risk of Type 2 Diabetes. Diabetes. 67 (Supplement 1), pp. 20-OR. https://doi.org/10.2337/db18-20-or

Hough, P. 2018. The effects of a three-week restricted carbohydrate diet on exercise metabolism and performance of three cyclists. Trends in Sport Sciences. 3 (25), pp. 117-125. https://doi.org/10.23829/TSS.2018.25.3-1

Pauly, Maude, Black, Antony P., Khampanisong, Phonepaseuth, Nouanthong, Phonethipsavanh, Hübschen, Judith M, Nanthavong, Naphavanh, Sayasinh, Kong, Jutavijittum, Prapan, Samountry, Bounthome, Xeuatvongsa, Anonh, Diedrich, Sabine and Muller, Claude P. 2018. Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study. PLoS ONE. 13 (5) e0197370. https://doi.org/10.1371/journal.pone.0197370

Khounvisith, Vilaysone, Tritz, Silvia, Khenkha, Latdavone, Phoutana, Vannaphone, Keosengthong, Amphone, Pommasichan, Sisavath, Nouanthong, Phonethipsavanh, Hübschen, Judith M, Snoeck, Chantal J, Reinharz, Daniel, Muller, Claude P., Black, Antony P. and Pauly, Maude 2018. High circulation of hepatitis E virus in pigs and professionals exposed to pigs in Laos. Zoonoses and Public Health. 65 (8), pp. 1020-1026. https://doi.org/10.1111/zph.12520

Okunade, K.S., Olowoselu, O.F., Osanyin, G.E., John-Olabode, S., Akanmu, S.A. and Anorlu, R.I. 2018. Selenium deficiency and pregnancy outcome in pregnant women with HIV in Lagos, Nigeria. International Journal of Gynecology & Obstetrics. 142 (2), pp. 207-213. https://doi.org/10.1002/ijgo.12508

Tritz, Silvia E, Khounvisith, Vilaysone, Pommasichan, Sisavath, Ninnasopha, Khampasong, Keosengthong, Amphone, Phoutana, Vannaphone, Camoin, Margot, Hübschen, Judith M, Black, A., Muller, Claude P and others 2018. Evidence of increased Hepatitis E virus exposure in Lao villagers with contact to ruminants. Zoonoses and public health. 65 (6), pp. 690-701. https://doi.org/10.1111/zph.12483

Xaydalasouk, Kinnaly, Strobel, Michel, Buisson, Yves, Black, A. and Muller, Claude P 2018. Seroprevalence and risk factors of hepatitis B and C virus infections in female workers of Lao garment factories. PLoS ONE. https://doi.org/10.1371/journal.pone.0199919

Triantafyllou, E., Pop, O.T., Possamai, L.A., Wilhelm, A., Liaskou, E., Singanayagam, A., Bernsmeier, C., Khamri, W., Petts, G., Dargue, R., Davies, S.P., Tickle, J., Yuksel, M., Patel, V.C., Abeles, R.D., Stamataki, Z., Curbishley, S.M., Ma, Y., Wilson, I.D., Coen, M., Woollard, K.J., Quaglia, A., Wendon, J., Thursz, M.R., Adams, D.H., Weston, C.J. and Antoniades, C.G. 2018. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. Gut. 67, pp. 333-347. https://doi.org/10.1136/gutjnl-2016-313615

Yuksel, M., Xiao, X., Tai, N., Vijay, G.M., Gülden, E., Beland, K., Lapierre, P., Alvarez, F., Hu, Z., Colle, I., Ma, Y. and Wen, L. 2018. The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model. Clinical and Experimental Immunology. 192 (1), pp. 164-176. https://doi.org/10.1111/cei.12843

William Cross, Michal Kovac, Ville Mustonen, Daniel Temko, Hayley Davis, Ann-Marie Baker, Sujata Biswas, Roland Arnold, Laura Chegwidden, Chandler Gatenbee, Alexander R.A. Anderson, Viktor Koelzer, Pierre Martinez, Xiaowei Jiang, Enric Domingo, Dan J. Woodcock, Yun Feng, Monika Kovacova, Tim Maughan, Richard Adams, Simon Bach, Andrew Beggs, Louise Brown, Francesca Buffa, Jean-Baptiste Cazier, Enric Domingo, Andrew Blake, Che-Hsi Wu, Ekaterina Chatzpili, Susan Richman, Philip Dunne, Paul Harkin, Geoff Higgins, Jim Hill, Chris Holmes, Denis Horgan, Rick Kaplan, Richard Kennedy, Mark Lawler, Simon Leedham, Tim Maughan, Ultan McDermott, Gillies McKenna, Gary Middleton, Dion Morton, Graeme Murray, Phil Quirke, Manuel Salto-Tellez, Les Samuel, Anna Schuh and David Sebag-Montefiore 2018. The evolutionary landscape of colorectal tumorigenesis. Nature Ecology & Evolution. 2, pp. 1661-1672. https://doi.org/10.1038/s41559-018-0642-z

Evans, G.H., Mattin, L.R., Ireland, I., Harrison, W., Yau, A.M.W., McIver, V., Pocock, T., Sheader, E. and James, L.J. 2018. Bolus ingestion of whey protein immediately post-exercise does not influence rehydration compared to energy-matched carbohydrate ingestion. Nutrients. 10 (6) 769. https://doi.org/10.3390/nu10060769

Mattin, L.R., Yau, A.M.W., McIver, V., James, L.J. and Evans, G.H. 2018. The effect of exercise intensity on gastric emptying rate, appetite and gut derived hormone responses after consuming a standardised semi-solid meal in healthy males. Nutrients. 10 (6) 787. https://doi.org/10.3390/nu10060787

Matthews, B.J., Dudchenko, O., Kingan, S.B., Koren, S., Antoshechkin, I., Crawford, J.E., Glassford, W.J., Herre, M., Redmond, S.N., Rose, N.H., Weedall, G.D., Wu, Y., Batra, S.S., Vosshall, L.B. and Partridge, F. 2018. Improved reference genome of Aedes aegypti informs arbovirus vector control. Nature. 563, pp. 501-507. https://doi.org/10.1038/s41586-018-0692-z

Furutani, S., Ihara, M., Lees, K., Buckingham, S.D., Partridge, F.A., David, J.A., Patel, R., Warchal, S., Mellor, I.R., Matsuda, K. and Sattelle, D.B. 2018. The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease. International Journal for Parasitology: Drugs and Drug Resistance. 8 (2), pp. 350-360. https://doi.org/10.1016/j.ijpddr.2018.06.001

Partridge, F.A., Forman, R., Willis, N.J., Bataille, C.J.R., Murphy, E.A., Brown, A.E., Heyer-Chauhan, N., Bruno Marinič, B., Sowood, D.J.C., Wynne, G.M., Else, K.J., Russell, A.J. and Sattelle, D.B. 2018. 2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm. PLoS Neglected Tropical Diseases. 12 (7) e0006487. https://doi.org/10.1371/journal.pntd.0006487

Partridge, F.A., Forman, R., Willis, N.J., Bataille, C.J.R., Murphy, E.A., Brown, A.E., Heyer-Chauhan, N., Bruno Marinič, B., Sowood, D.J.C., Wynne, G.M., Else, K.J., Russell, A.J. and Sattelle, D.B. 2018. Preprint: 2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm. biorxiv.org. https://doi.org/10.1101/254037

Partridge, F.A., Brown, A.E., Buckingham, S.D., Willis, N.J., Wynne, G.M., Forman, R., Else, K.J., Morrison, A.A., Matthews, J.B., Russell, A.J., Lomas, D.A. and Sattelle, D.B. 2018. An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes. International Journal for Parasitology: Drugs and Drug Resistance. 8 (1), pp. 8-21. https://doi.org/10.1016/j.ijpddr.2017.11.004

Foster, J.M., Kamal, I.H., Daub, J., Swan, M.C., Ingram, J.R., Ganatra, M., Ware, J., Guiliano, D.B., Aboobaker, A., Moran, L., Blaxter, M. and Slatko, B.E. 2018. Hybridization to High-Density Filter Arrays of a Brugia malayi BAC Library with Biotinylated Oligonucleotides and PCR Products. BioTechniques. 30 (6), pp. 1216-1224. https://doi.org/10.2144/01306bm06

Brayson, D., Ho, C.Y. and Shanahan, C.M. 2018. Muscle tensions merge to cause a DNA replication crisis. The Journal of Cell biology. 217 (6), pp. 1891-1893. https://doi.org/10.1083/jcb.201804041

Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Munir Ahmad, Gema Vizcay-Barrena, Andrea Protti, Peter S. Zammit, Cristobal G. dos Remedios, Elisabeth Ehler, Ajay M. Shah and Catherine M. Shanahan 2018. Preprint: Accumulation of prelamin A drives inflammation in the heart with implications for treatment of inherited and acquired cardiomyopathies. biorxiv.org. https://doi.org/10.1101/457044

Augusto C. Montezano, Livia De Lucca Camargo, Patrik Persson, Francisco J. Rios, Adam P. Harvey, Aikaterini Anagnostopoulou, Roberto Palacios, Ana Caroline P. Gandara, Rheure Alves‐Lopes, Karla B. Neves, Maria Dulak‐Lis, Chet E. Holterman, Pedro Lagerblad de Oliveira, Delyth Graham, Christopher Kennedy and Rhian M. Touyz 2018. NADPH Oxidase 5 Is a Pro‐Contractile Nox Isoform and a Point of Cross‐Talk for Calcium and Redox Signaling‐Implications in Vascular Function. Journal of the American Heart Association. 7 (12) e009388. https://doi.org/10.1161/jaha.118.009388

Rhian M Touyz, Rheure Alves-Lopes, Francisco J Rios, Livia L Camargo, Aikaterini Anagnostopoulou, Anders Arner and Augusto C Montezano 2018. Vascular smooth muscle contraction in hypertension. Cardiovascular Research. 114 (4), pp. 529-539. https://doi.org/10.1093/cvr/cvy023

Giganti, F., Gambarota, G., Moore, C.M., Robertson, N.L., Mccartan, N., Jameson, C., Bott, S.R., Winkler, M., Whitcher, B., Castro-Santamaria, R., Emberton, M., Allen, C. and Kirkham, A. 2018. Prostate cancer detection using quantitative T2 and T2-weighted imaging: The effects of 5-alpha-reductase inhibitors in men on active surveillance. Journal of Magnetic Resonance Imaging. 47 (6), pp. 1646-1653. https://doi.org/10.1002/jmri.25891

Kalampouka, I., Elliott, B. and van Bekhoven, A. 2018. Differing Effects of Younger and Older Human Plasma on C2C12 Myocytes in Vitro. Frontiers in Physiology. 9 (152). https://doi.org/10.3389/fphys.2018.00152