Life Sciences

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HeadProf Alistair Mathie
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Combined Ex Vivo 9.4T MRI and Quantitative Histopathological Study in Normal and Pathological Neocortical Resections in Focal Epilepsy

Journal article

Reeves, C., Tachrount, M., Thomas, D., Michalak, Z., Liu, J.Y.W., Ellis, M., Diehl, B., Miserocchi, A., McEvoy, A.W., Eriksson, S., Yousry, T. and Thom, M. 2016. Combined Ex Vivo 9.4T MRI and Quantitative Histopathological Study in Normal and Pathological Neocortical Resections in Focal Epilepsy. Brain Pathology. 26 (3), pp. 319-333. https://doi.org/10.1111/bpa.12298

Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function.

Journal article

Thomson, P.A., Duff, B., Blackwood, D.H., Romaniuk, L., Watson, A., Whalley, H.C., Li, X., Dauvermann, M.R., Moorhead, T.W., Bois, C., Ryan, N.M., Redpath, H., Hall, L., Morris, S.W., van Beek, E.J., Roberts, N., Porteous, D.J., St Clair, D., Whitcher, B. and Dunlop, J. 2016. Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. Schizophrenia. 2 16024. https://doi.org/10.1038/npjschz.2016.24

Physical activity location and intensity across the school year: a mixed methods study

Conference paper

Khawaja, I., Collins, P., Woodfield, L., Nevill, A. and Safi, A. 2016. Physical activity location and intensity across the school year: a mixed methods study. International Society of Behavioural Nutrition and Physical Activity Annual Conference 2016. Cape Town International Convention Centre, Cape Town, South Africa 08 - 11 Jun 2016

The use of technology in measuring children’s physical activity

Conference paper

Khawaja, I., Collins, P., Woodfield, L., Nevill, A. and Safi, A. 2016. The use of technology in measuring children’s physical activity. Newman University’s Festival of Doctoral Research. Newman University, Birmingham, UK 07 Jul 2016

Gender differences in physical activity behaviour according to location

Conference paper

Khawaja, I., Collins, P., Woodfield, L., Nevill, A. and Safi, A. 2016. Gender differences in physical activity behaviour according to location. British Heart Foundation Physical Activity and Cardiovascular Health across the Lifespan Conference. Coventry University, Coventry, UK 06 Oct 2016

The psychological reasons for losing the winning game of cricket

Other

Safi, A. 2016. The psychological reasons for losing the winning game of cricket. BBC Pashto.

Genomic Variant Classifier Tool

Conference paper

Grau, I., Sengupta, D., Farid, D.M., Manderick, B., Nowe, A., Garcia Lorenzo, M.M., Daneels, D., Bonduelle, M., Croes, D. and Van Dooren , S. 2016. Genomic Variant Classifier Tool. SAI Intelligent Systems Conference 2016. London 21 Sep 2016 Springer. https://doi.org/10.1007/978-3-319-56994-9_32

GeVaCT - Genomic Variant Classifier Tool

Article

Daneels, D., Grau, I., Sengupta, D., Bonduelle, M.L., Farid, D., Croes, D., Nowé, A. and Van Dooren, S. 2016. GeVaCT - Genomic Variant Classifier Tool. European Journal of Human Genetics. 24 (E-Supplement 1), p. 341.

Grey-Box Model: An ensemble approach for addressing semi-supervised classification problems

Conference paper

Sengupta, D., Grau, I., Garcia Lorenzo, M.M. and Nowe, A. 2016. Grey-Box Model: An ensemble approach for addressing semi-supervised classification problems. Benelearn 2016: Belgian-Dutch Conference on Machine Learning. Katholieke Universiteit Leuven, Campus Kortrijk (KULAK) 12 - 13 Sep 2016

Systematic identification of phenotypically enriched loci using a patient network of genomic disorders

Journal article

Reyes-Palomares, A., Bueno, A., Rodríguez-López, R., Medina, M., Sánchez-Jiménez, F., Corpas, M. and Ranea, J.A.G. 2016. Systematic identification of phenotypically enriched loci using a patient network of genomic disorders. BMC Genomics. 17 232. https://doi.org/10.1186/s12864-016-2569-6

Progress on the genome characterisation of D. alata

Conference paper

Corpas, M. 2016. Progress on the genome characterisation of D. alata. Plant and Animal Genome XXIV Conference. Town & Country Resort & Convention Center 09 - 13 Jan 2016

Septins and Bacterial Infection

Journal article

Torraca, V. and Mostowy, Serge 2016. Septins and Bacterial Infection. Frontiers in Cell and Developmental Biology. https://doi.org/10.3389/fcell.2016.00127

Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses

Journal article

Kirkegaard, T., Gray, J., Priestman, D.A., Wallom, K.-L., Atkins, J., Olsen, O.D., Klein, A., Drndarski, S., Petersen, N.H.T., Ingemann, L., Smith, D.A., Morris, L., Bornæs, C., Jørgensen, S.H., Williams, I., Hinsby, A., Arenz, C., Begley, D., Jäättelä, M. and Platt, F.M. 2016. Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses. Science Translational Medicine. 8 (355), p. 355ra188 355ra188. https://doi.org/10.1126/scitranslmed.aad9823

Recent discoveries of influenza A drug target sites to combat virus replication

Journal article

Patel, H. and Kukol, A 2016. Recent discoveries of influenza A drug target sites to combat virus replication. Biochemical Society Transactions. 44 (3), pp. 932-936. https://doi.org/10.1042/BST20160002

Evaluation of a novel virtual screening strategy using receptor decoy binding sites

Journal article

Patel, H. and Kukol, A. 2016. Evaluation of a novel virtual screening strategy using receptor decoy binding sites. Journal of Negative Results in BioMedicine. 15, pp. 1-5. https://doi.org/10.1186/s12952-016-0058-8

STAT1 activation in association with JAK2 exon 12 mutations

Journal article

Godfrey, A.L., Chen, E., Massie, C.E., Silber, Y., Pagano, F., Bellosillo, B., Guglielmelli, P., Harrison, C.N., Reilly, J.T., Stegelmann, F., Bijou, F., Lippert, E., Boiron, J.M., Dohner, K., Vannucchi, A.M., Besses, C. and Green, A.R. 2016. STAT1 activation in association with JAK2 exon 12 mutations. Haematologica. 101, pp. e15-e19. https://doi.org/10.3324/haematol.2015.128546

Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9

Journal article

Schneider, R.K., Schenone, M., Ferreira, M.V., Kramann, R., Joyce, C.E., Hartigan, C., Beier, F., Brümmendorf, T.H., Germing, U., Platzbecker, U., Busche, G., Knuchel, R., Chen, M.C., Waters, C.S., Chen, E., Chu, L.P., Novina, C.D., Lindsley, R.C., Carr, S.A. and Ebert, B.L. 2016. Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. Nature Medicine. 22, pp. 288-297. https://doi.org/10.1038/nm.4047

JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation

Journal article

Ahn, J.S., Li, J., Chen, E., Kent, D.G., Park, H.J. and Green, A.R. 2016. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 35, pp. 2235-2246. https://doi.org/10.1038/onc.2015.285

Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation

Journal article

Elf, S., Abdelfattah, N.S., Chen, E., Perales-Patón, J., Rosen, E.A., Ko, A., Peskier, F., Florescu, N., Giannini, S., Wolach, O., Morgan, E.A., Tothova, Z., Losman, J.A., Schneider, R.K., Al-Shahrour, F. and Mullally, A. 2016. Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation. Cancer Discovery. 6, pp. 368-381. https://doi.org/10.1158/2159-8290.CD-15-1434

Reverse left ventricular remodeling: Effect of cardiac rehabilitation exercise training in myocardial infarction patients with preserved ejection fraction

Journal article

McGregor, G., Gaze, D.C., Oxborough, D., O'Driscoll, J. and Shave, R. 2016. Reverse left ventricular remodeling: Effect of cardiac rehabilitation exercise training in myocardial infarction patients with preserved ejection fraction. European Journal of Physical and Rehabilitation Medicine. 52 (3), pp. 370-378.

Perioperative kinetics of endocan in patients undergoing cardiac surgery with and without cardiopulmonary bypass

Journal article

Madhivathanan, P., Fletcher, N., Gaze, D.C., Thomson, R., Chandrasekaran, V., Al-Subaie, N., Valencia, O. and Sharma, V. 2016. Perioperative kinetics of endocan in patients undergoing cardiac surgery with and without cardiopulmonary bypass. Cytokine. 93, pp. 8-12. https://doi.org/10.1016/j.cyto.2016.03.006

The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: A new approach to risk assessment and disease prevention

Journal article

Lazzarino, A., Hamer, M., Gaze, D.C., Collinson, P., Rumley, A., Lowe, G. and Steptoe, A. 2016. The interaction between systemic inflammation and psychosocial stress in the association with cardiac troponin elevation: A new approach to risk assessment and disease prevention. Preventive Medicine. 93, pp. 46-52. https://doi.org/10.1016/j.ypmed.2016.09.018

Rapid Cardiovascular Diagnostics

Book chapter

Gaze, D.C. 2016. Rapid Cardiovascular Diagnostics. in: Saxena, S.K. (ed.) Proof and Concepts in Rapid Diagnostic Tests and Technologies Croatia InTech Publishing.

A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma

Journal article

Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A.P., Chayka, O., Regad, T., Pistorio, A., Sementa, A.R., Virasami, A., Barton, A., Montano, X., Lechertier, T., Brindle, N., Morgenstern, D., Lebras, M., Burns, A.J., Saunders N.J., Hodivala-Dilke, K., Bagella, L., De The, H., Anderson, J., Sebire, N., Pistoia, V., Sala, A. and Salomoni, P. 2016. A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma. Clinical Cancer Research. 22 (13), pp. 3398-3409. https://doi.org/10.1158/1078-0432.CCR-15-2081

Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections

Journal article

Tai, X., Koepp, M., Duncan, J., Fox, N., Thompson, P., Baxendale, S., Liu, J., Reeves, C., Michalak, Z. and Thom, M. 2016. Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections. Brain. 139 (9), pp. 2441-55. https://doi.org/10.1093/brain/aww187

Bioavailability and metabolism of ccompounds from wholegrain wheat and aleurone‐rich wheat bread

Journal article

Bresciani, L., Scazzina, F., Leonardi, R., Dall’Aglio, E., Newell, M., Dall’Asta, M., Melegari, C., Ray, S., Brightenti, F. and Del Rio, D. 2016. Bioavailability and metabolism of ccompounds from wholegrain wheat and aleurone‐rich wheat bread. Molecular Nutrition & Food Research. 60 (11), pp. 2343-2354. https://doi.org/10.1002/mnfr.201600238

Early lipofuscin accumulation in Frontal Lobe Epilepsy

Journal article

Liu, J., Reeves, C., Diehl, B., Coppola, A., Al-Hajri, A., Hoskote, C., Mughairy, S., Tachrount, M., Groves, M., Michalak, Z., Mills, K., McEvoy, A., Miserocchi, A., Sisodiya, S. and Thom, M. 2016. Early lipofuscin accumulation in Frontal Lobe Epilepsy. Annals of Neurology. 80, pp. 882-895. https://doi.org/10.1002/ana.24803

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

Journal article

Norling, L., Headland, S., Dalli, J., Arnardottir, H., Haworth, O., Jones, H., Irimia, D., Serhan, C. and Perretti, M. 2016. Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. JCI Insight. 1 (5), p. e85922 e85922. https://doi.org/10.1172/jci.insight.85922

Genomic analyses inform on migration events during the peopling of Eurasia

Journal article

Gerbault, P. 2016. Genomic analyses inform on migration events during the peopling of Eurasia. Nature. 538 (7624), pp. 238-242. https://doi.org/10.1038/nature19792

Whole Genome Sequencing Provides Insights into the Genetic Determinants of Invasiveness in Salmonella Dublin

Journal article

Mohammed, M. and Cormican, M. 2016. Whole Genome Sequencing Provides Insights into the Genetic Determinants of Invasiveness in Salmonella Dublin. Epidemiology and Infection. 144 (11), pp. 2430-2439. https://doi.org/10.1017/S0950268816000492

Whole genome sequencing provides an unambiguous link between Salmonella Dublin outbreak strain and a historical isolate

Journal article

Mohammed, M., Delappe, N., O'Connor, J., McKeown, P., Garvey, P. and Cormican, M. 2016. Whole genome sequencing provides an unambiguous link between Salmonella Dublin outbreak strain and a historical isolate. Epidemiology and Infection. 144 (3), pp. 576-581. https://doi.org/10.1017/S0950268815001636

Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: Recommendations for saturation divers

Journal article

Deb, S., Swinton, P. and Dolan, E. 2016. Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: Recommendations for saturation divers. Extreme Physiology and Medicine. 7 (5), p. 1 1. https://doi.org/10.1186/s13728-015-0042-9

Brief communication: Self-reported health and activity habits and attitudes in saturation divers

Article

Dolan, E., Deb, S., Stephan, G. and Swinton, P. 2016. Brief communication: Self-reported health and activity habits and attitudes in saturation divers. Undersea and Hyperbaric Medicine: journal of the Undersea and Hyperbaric Medical Society. 43 (2), pp. 93-101.

Recent Developments in the Use of Sodium Bicarbonate as an Ergogenic Aid

Journal article

McNaughton, L., Bentley, D., Deb, S., Gough, L. and Sparks, S.A. 2016. Recent Developments in the Use of Sodium Bicarbonate as an Ergogenic Aid. Current Sports Medicine Reports. 15 (4), pp. 233-244. https://doi.org/10.1249/JSR.0000000000000283

Enhancing electricity production from wastewater using microbial fuel cells

Conference paper

Fapetu, S., Keshavarz, T., Clements, M.O. and Kyazze, G. 2016. Enhancing electricity production from wastewater using microbial fuel cells. Postgraduate Fair 2016. NCS, University of Westminster 28 Apr 2016

Biomarkers in Cardiovascular Disease (Biomarkers in Disease: Methods, Discoveries and Applications)

Book

Patel, V.B and Preedy, V.R. (ed.) 2016. Biomarkers in Cardiovascular Disease (Biomarkers in Disease: Methods, Discoveries and Applications). Springer.

L-Arginine in Clinical Nutrition (Nutrition and Health)

Book

Patel, V., Preedy, V.R. and Rajendram, R. (ed.) 2016. L-Arginine in Clinical Nutrition (Nutrition and Health). Humana Press.

Influence of electrolytes in mediating Pseudomonas aeruginosa PAO1 biofilm composition and virulence factors

Conference poster

Kalgudi, R., Kyazze, G. and Keshavarz, T. 2016. Influence of electrolytes in mediating Pseudomonas aeruginosa PAO1 biofilm composition and virulence factors. Biofilms 7: Microbial Works of Art. Porto, Portugal 26 - 28 Jun 2016 Universidade do Minho.

The formyl peptide receptor 2 (Fpr2) agonist, Compound 43 (Cpd43), attenuates and promotes the release of pro-inflammatory, and anti-inflammatory cytokines, respectively

Conference keynote

Wickstead, E., Getting, S.J. and McArthur, S. 2016. The formyl peptide receptor 2 (Fpr2) agonist, Compound 43 (Cpd43), attenuates and promotes the release of pro-inflammatory, and anti-inflammatory cytokines, respectively. British Pharmacological Society: Pharmacology 2016. London 13 - 15 Dec 2016

Data-driven model of the hippocampus using the HBP Brain Simulation Platform

Conference poster

Romani, A., Antille, N., Atenekeng, G., Courcol, J.D., Devresse, A., Dynes, J.A., Gevaert, M., Gonzalo, J.K., Gulyas, A., Kali, S., Kanari, L., Lange, S., Mercer, A., Migliore, M., Muller, E.B., Palacios, J.P., Ramaswamy, S., Reimann, M., Riquelme, R.L., Rössert, C.A., Ying, S., Shillcock, J., Telefont, M., Van Geit, W.A.H., Vanherpe, L., Markram, H. and Thomson, A. 2016. Data-driven model of the hippocampus using the HBP Brain Simulation Platform. 10th FENS Forum of Neuroscience. Copenhagen, Denmark 02 - 06 Jul 2016


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