Life Sciences

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HeadProf Alistair Mathie
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Adipocyte pyruvate dehydrogenase kinase 4 expression is associated with augmented PPARγ upregulation in early-life programming of later obesity

Article

Holness, M.J., Zariwala, M., Walker, C.G. and Sugden, M.C. 2012. Adipocyte pyruvate dehydrogenase kinase 4 expression is associated with augmented PPARγ upregulation in early-life programming of later obesity. FEBS Open Bio. 2, pp. 32-36. https://doi.org/10.1016/j.fob.2012.02.003

Evaluating demographic models for goat domestication using mtDNA sequences

Article

Gerbault, P., Powell, A. and Thomas, M.G. 2012. Evaluating demographic models for goat domestication using mtDNA sequences. Anthropozoologica. 47 (2), pp. 64-76. https://doi.org/10.5252/az2012n2a5

Domestication and migrations: Using mitochondrial DNA to infer domestication processes of goats and horses

Book chapter

Gerbault, P., Leonardi, M., Powell, A., Weber, C., Benecke, N., Burger, J. and Thomas, M.G. 2012. Domestication and migrations: Using mitochondrial DNA to infer domestication processes of goats and horses. in: Kaiser, E., Burger, J. and Schier, Wo (ed.) Population Dynamics in Prehistory and Early History: New Approaches Using Stable Isotopes and Genetics. Berlin, Germany De Grutyer. pp. 17-30

Inferring processes of Neolithic gene-culture co-evolution using genetic and archaeological data: The case of lactase persistence and dairying

Book chapter

Gerbault, P., Bollongino, R., Burger, J. and Thomas, M.G. 2012. Inferring processes of Neolithic gene-culture co-evolution using genetic and archaeological data: The case of lactase persistence and dairying. in: Colledge, S., Conolly, J., Dobney, K., Manning, K. and Shennan, S. (ed.) The Origins and Spread of Domestic Animals in Southwest Asia and Europe Walnut Creek, CA Left Coast Press. pp. 37-48

The evolution of lactase persistence in Europe. A synthesis of archaeological and genetic evidence

Article

Leonardi, M, Gerbault, P., Thomas, M.G. and Burger, J. 2012. The evolution of lactase persistence in Europe. A synthesis of archaeological and genetic evidence. International Dairy Journal. 22 (2), pp. 88-97. https://doi.org/10.1016/j.idairyj.2011.10.010

Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer

Article

Darrington, R.S., Campa, V.M., Walker, M.M., Bengoa-Vergniory, N., Gorrono-Etxebarria, I., Uysal-Onganer, P., Kawano, Y., Waxman, J. and Kypta, R.M. 2012. Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer. International Journal of Cancer. 131 (6), p. E872–E883. https://doi.org/10.1002/ijc.27620

Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids

Article

Zhang, Q., Raheem, S., Botting, N.P., Slawin, A.M.Z., Kay, C.D. and O’Hagan, D. 2012. Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids. Tetrahedron. 68, pp. 4194-4201. https://doi.org/10.1016/j.tet.2012.03.100

Microvesicles in Health and Disease

Article

Inal, J.M., Ansa-Addo, E.A., Stratton, D., Kholia, S., Antwi-Baffour, S., Jorfi, S. and Lange, S. 2012. Microvesicles in Health and Disease. Archivum Immunologiae et Therapiae Experimentalis. 60 (2), pp. 107-121. https://doi.org/10.1007/s00005-012-0165-2

TNF gene deletion prevents lipopolysaccharide-mediated sensitisation of the neonatal mouse brain to hypoxic-ischaemic insult

Article

Sahota, A., Kendall, G., Lange, S. and Raivich, G. 2012. TNF gene deletion prevents lipopolysaccharide-mediated sensitisation of the neonatal mouse brain to hypoxic-ischaemic insult. BMC Proceedings. 6 (Suppl 4), p. O9. https://doi.org/10.1186/1753-6561-6-S4-O9

Characterisation of microvesicles released from cells constitutively and upon stimulation

Article

Stratton, D., Antwi-Baffour, S., Williams, G., Grant, R., Lange, S. and Inal, J.M. 2012. Characterisation of microvesicles released from cells constitutively and upon stimulation. Journal of Extracellular Vesicles. 1.

Isolation of microvesicles and exosomes by filtration and estimation of normal reference range in blood plasma

Article

Grant, R., Ansa-Addo, E., Stratton, S., Antwi-Baffour, S., Jorfi, S., Kholia, S., Krige, L., Lange, S. and Inal, J.M. 2012. Isolation of microvesicles and exosomes by filtration and estimation of normal reference range in blood plasma. Journal of Extracellular Vesicles. 1.

The intracellular parasite, Trypanosoma cruzi, utilizes microvesicle release to invade host cells

Article

Inal, J.M., Ansa-Addo, E., Cestari, I., Pathak, P.I., McCrossan, M.V., Lange, S. and Ramirez, M. 2012. The intracellular parasite, Trypanosoma cruzi, utilizes microvesicle release to invade host cells. Journal of Extracellular Vesicles. 1.

The effect of hypoxia and work intensity on insulin resistance in type 2 diabetes

Journal article

MacKenzie, R., Elliott, B., Maxwell, N.S., Brickley, G. and Watt, P.W. 2012. The effect of hypoxia and work intensity on insulin resistance in type 2 diabetes. Journal of Clinical Endocrinology and Metabolism. 97 (1), pp. 155-62. https://doi.org/10.1210/jc.2011-1843

Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with type 2 diabetes

Journal article

MacKenzie, R., Maxwell, N.S., Castle, P.C., Elliott, B., Brickley, G. and Watt, P.W. 2012. Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism. 97 (4), pp. 46-55. https://doi.org/10.1210/jc.2011-2829

The central role of myostatin in skeletal muscle and whole body homeostasis

Journal article

Elliott, B., Renshaw, D., Getting, S.J. and MacKenzie, R. 2012. The central role of myostatin in skeletal muscle and whole body homeostasis. Acta Physiologica. 205 (3), pp. 324-40. https://doi.org/10.1111/j.1748-1716.2012.02423.x

The genus Caligus Müller, 1785 (Copepoda: Siphonostomatoida): two new species from reef associated fishes in New Caledonia, and some nomenclatural problems resolved

Article

Hayes, P.M., Justine, J.-L. and Boxshall, G. 2012. The genus Caligus Müller, 1785 (Copepoda: Siphonostomatoida): two new species from reef associated fishes in New Caledonia, and some nomenclatural problems resolved. Zootaxa. 3534, pp. 21-39.

Respiratory and non-respiratory sinus arrhythmia: implications for heart rate variability

Journal article

McMullen, M.K., Whitehouse, J., Towell, A. and Rhodes, G. 2012. Respiratory and non-respiratory sinus arrhythmia: implications for heart rate variability. Journal of Clinical Monitoring and Computing. 26 (1), pp. 21-28. https://doi.org/10.1007/s10877-011-9327-8

Complementary Medicine and Science: Uncomfortable Bedfellows?

Article

Shine, G. and Rhodes, G. 2012. Complementary Medicine and Science: Uncomfortable Bedfellows? The International Journal of Science in Society. 3 (1), pp. 167-175.

Foundation degrees in biomedical science: the student experience

Article

Ferrier, C., Brookwell, K., Quinn, P., Ms Kelly Brookwell and Mr Paul Quinn 2012. Foundation degrees in biomedical science: the student experience. Biomedical Scientist. 56 (9), pp. 560 - 561.

γ-Heptalactone is an endogenously produced quorum-sensing molecule regulating growth and secondary metabolite production by Aspergillus nidulans

Article

Williams, H.E., Steele, J.C.P., Clements, M.O. and Keshavarz, T. 2012. γ-Heptalactone is an endogenously produced quorum-sensing molecule regulating growth and secondary metabolite production by Aspergillus nidulans. Applied Microbiology and Biotechnology. 96 (3), pp. 773-781. https://doi.org/10.1007/s00253-012-4065-5

Application repository and science gateway for running molecular docking and dynamics simulations

Book chapter

Terstyanszky, G., Kiss, T., Kukla, T., Lichtenberger, Z., Winter, S., Greenwell, P., McEldowney, S. and Heindl, H. 2012. Application repository and science gateway for running molecular docking and dynamics simulations. in: Gesing, S., Glatard, T., Kruger, J., Delgado Olabarriaga, S., Solomonides, T., Silverstein, J.C., Montagnat, J., Gaignard, A. and Krefting, D. (ed.) Healthgrid applications and technologies meet science gateways for life sciences IOS Press.

Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population

Journal article

Taylor, A.E., Kuper, H., Varma, R.D., Wells, J.C.K., Bell, J.D., Radhakrishna, K.V., Kulkarni, B., Kinra, S., Timpson, N.J., Ebrahim, S., Smith, G.D. and Ben-Shlomo, Y. 2012. Validation of dual energy x-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population. PLoS ONE. 7 (12) e51042. https://doi.org/10.1371/journal.pone.0051042

Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy

Article

Solanky, B.S., Sanchez-Canon, G.J., Cobbold, J.F.L., Taylor-Robinson, S.D., Bell, J.D., Scudamore, C.L., Ross, E., Holder, J.C., So, P.W. and Cox, I.J. 2012. Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy. Toxicological Sciences. 126 (2), pp. 306-316. https://doi.org/10.1093/toxsci/kfs019

Do public health messages impact on knowledge, diet and lifestyle choices of women during pregnancy?

Article

Salisbury, C. and Robertson, C.E. 2012. Do public health messages impact on knowledge, diet and lifestyle choices of women during pregnancy? International Journal of Food, Nutrition and Public Health. 5 (4), pp. 225-247.

The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer

Article

Rambaruth, N.D.S., Greenwell, P. and Dwek, M. 2012. The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer. Glycobiology. 22 (6), pp. 839-848. https://doi.org/10.1093/glycob/cws051

Ozone therapy

Report

Pilkington, K. and CAM-Cancer Consortium 2012. Ozone therapy. CAM-Cancer Database National Information Center for Complementary and Alternative Medicine (NIFAB).

Noni (Morinda citrifolia)

Report

Pilkington, K. and CAM-Cancer Consortium 2012. Noni (Morinda citrifolia). CAM-Cancer Database National Information Center for Complementary and Alternative Medicine (NIFAB).

Echinacea spp

Report

Pilkington, K. and CAM-Cancer Consortium 2012. Echinacea spp. CAM-Cancer Database CAM-Cancer Consortium (Complementary and Alternative Medicine for Cancer).

The placebo response in migraine treatment

Book chapter

Peters, D. 2012. The placebo response in migraine treatment. in: Fernández-de-las-Peñas, C., Chaitow, L. and Schoenen, J. (ed.) Multidisciplinary management of migraine: pharmacological, manual, and other therapies Sudbury, Maryland Jones & Bartlett Learning. pp. 313-326

Cardiac expression of STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4

Article

Ounzain, S., Kobayashi, S., Peterson, R., He, A., Samani, N.J., Menick, D.R., Pu, W.T., Liang, Q. and Chong, Nelson W. 2012. Cardiac expression of STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Molecular and Cellular Biology. 32 (10), pp. 1830-1843. https://doi.org/10.1128/MCB.06374-11

Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana

Conference paper

Opoku-Okrah, C., Smith, C.L., Gordge, M.P., Parry, M., Robertson, C.E., Abgenyega, T. and Nakua, E. 2012. Alpha thalassaemia and the severity of Plasmodium falciparum infection in microcytic children from the Ashanti region of Ghana. British Society for Haematology 52nd meeting. Glasgow 16-18 April 2012

Kisspeptin prevention of Amyloid-β Peptide neurotoxicity in vitro

Article

Milton, N.G.N., Chilumuri, A., Rocha-Ferreira, E., Nercessian, A.N. and Ashioti, M. 2012. Kisspeptin prevention of Amyloid-β Peptide neurotoxicity in vitro. ACS chemical neuroscience. 3 (9), pp. 706-719. https://doi.org/10.1021/cn300045d

Cells, tissues and organs of the immune system

Book chapter

Lydyard, P.M. and Porakishvili, N. 2012. Cells, tissues and organs of the immune system. in: Male, D., Brostoff, J., Roth, D.B. and Roitt, I.M. (ed.) Immunology (8th edition) Elsevier. pp. 17-50

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics

Article

Loo, R.L., Chan, Q., Brown, I.J., Robertson, C.E., Stamler, J., Nicholson, J.K., Holmes, E. and Elliott, P. 2012. A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics. American Journal of Epidemiology. 175 (4), pp. 348-358. https://doi.org/10.1093/aje/kwr292

What shapes participation in a community-based intervention? Evidence from a qualitative evaluation of the well London project

Article

Jain, S., Draper, A., Clow, A., Lynch, R. and Derges, J. 2012. What shapes participation in a community-based intervention? Evidence from a qualitative evaluation of the well London project. Journal of Epidemiology & Community Health. 66 (S1), p. A3. https://doi.org/10.1136/jech-2012-201753.007

Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue

Article

Hankir, M., Bueter, M., Gsell, W., Seyfried, F., Khalil, M., Smith, K.L., Bloom, S.R., Bell, J.D. and le Roux, C.W. 2012. Increased energy expenditure in gastric bypass rats is not caused by activated brown adipose tissue. Obesity Facts. 5 (3), pp. 349-358. https://doi.org/10.1159/000339742

Chinese herbal products in the prevention and treatment of liver disease

Book chapter

Gyamfi, D., Everitt, H.E. and Patel, V. 2012. Chinese herbal products in the prevention and treatment of liver disease. in: Watson, R.R. and Preedy, V.R. (ed.) Bioactive food as dietary interventions for liver and gastrointestinal disease Academic Press. pp. 537-550

Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system

Article

Gavins, F.N.E., Hughes, E.L., Buss, N.A.P.S., Holloway, P.M., Getting, S.J. and Buckingham, J.C. 2012. Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system. FASEB Journal. 26 (12), pp. 4977-4989. https://doi.org/10.1096/fj.12-205971

Enhanced production of the polyhydroxyalkanoate, P(3HB), from cacillus cereus SPV and its applications in cartilage regeneration

Conference paper

Everest, A., Keshavarz, T. and Roy, I. 2012. Enhanced production of the polyhydroxyalkanoate, P(3HB), from cacillus cereus SPV and its applications in cartilage regeneration. Gordon Research Conference on Biopolymers. Salve Regina University, Newport, Rhode Island, USA 3-8 June 2012

The central role of myostatin in skeletal muscle and whole body homeostasis

Article

Elliott, B.T., Renshaw, D., Getting, S.J. and Mackenzie, R.W.A. 2012. The central role of myostatin in skeletal muscle and whole body homeostasis. Acta Physiologica. 205 (3), pp. 324-340. https://doi.org/10.1111/j.1748-1716.2012.02423.x


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