Life Sciences

Thom, M., Liu, J.Y.W., Thompson, P., Phadke, R., Narkiewicz, M., Martinian, L., Marsdon, D., Koepp, M., Caboclo, L., Catarino, C.B. and Sisodiya, S.M. 2011. Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: A post-mortem study. Brain. 134 (10), pp. 2969-2981. https://doi.org/10.1093/brain/awr209

Catarino, C.B., Liu, J.Y.W., Liagkouras, I., Gibbons, V.S., Labrum, R.W., Ellis, R., Woodward, C., Davis, M.B., Smith, S.J., Cross, J.H., Appleton, R.E., Yendle, S.C., McMahon, J.M., Bellows, S.T., Jacques, T.S., Zuberi, S.M., Koepp, M.J., Martinian, L., Scheffer, I.E., Thom, M. and Sisodiya, S.M. 2011. Dravet syndrome as epileptic encephalopathy: Evidence from long-term course and neuropathology. Brain. 134 (10), pp. 2982-3010. https://doi.org/10.1093/brain/awr129

O'Connor, J.P.B., Rose, C.J., Jackson, A., Watson, Y., Cheung, S., Maders, F., Whitcher, B.J., Roberts, C., Buonaccorsi, G.A., Thompson, G., Clamp, A.R., Jayson, G.C. and Parker, G.J.M. 2011. DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6. British Journal of Cancer. 105, pp. 139-145. https://doi.org/10.1038/bjc.2011.191

Tzimopoulou, S., Cunningham, V.J., Nichols, T.E., Searle, G., Bird, N.P., Mistry, P., Dixon, I.J., Hallett, W.A., Whitcher, B., Brown, A.P., Zvartau-Hind, M., Lotay, N., Lai, R.Y.K., Castiglia, M., Jeter, B., Matthews, J.C., Chen, K., Bandy, D., Reiman, E.M., Gold, M., Rabiner, E.A. and Matthews, P.M. 2011. Validation and pilot application of [ 18F]FDG-PET in evaluation of a metabolic therapy for Alzheimer's disease. Advances in Alzheimer's Disease. 2, pp. 627-642. https://doi.org/10.3233/978-1-60750-793-2-627

Tabelow, K., Clayden, J.D., Lafaye de Micheaux, P., Polzehl, J., Schmid, V.J. and Whitcher, B. 2011. Image analysis and statistical inference in neuroimaging with R. NeuroImage. 55 (4), pp. 1686-1693. https://doi.org/10.1016/j.neuroimage.2011.01.013

Douaud, G., Jbabdi, S., Behrens, T.E.J., Menke, R.A., Gass, A., Monsch, A.U., Rao, A., Whitcher, B., Kindlmann, G., Matthews, P.M. and Smith, S. 2011. DTI measures in crossing-fibre areas: Increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease. NeuroImage. 55 (3), pp. 880-890. https://doi.org/10.1016/j.neuroimage.2010.12.008

Whitcher, B. and Schmid, V.J. 2011. Quantitative analysis of dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging for oncology in R. Journal of Statistical Software. 44 (5), pp. 1-29. https://doi.org/10.18637/jss.v044.i05

Tabelow, K. and Whitcher, B. 2011. Special volume on Magnetic Resonance Imaging in R. Journal of Statistical Software. 44 (1), pp. 1-6. https://doi.org/10.18637/jss.v044.i01

Whitcher, B., Schmid, V.J. and Thornton, A. 2011. Working with the DICOM and NIfTI data standards in R. Journal of Statistical Software. 44 (6), pp. 1-29. https://doi.org/10.18637/jss.v044.i06

Tosun, D., Schuff, N., Mathis, C.A., Jagust, W., Weiner, M.W., Alzheimer's Disease NeuroImaging Initiative and Whitcher, B. 2011. Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment. Brain. 134 (4), p. 1077–1088. https://doi.org/10.1093/brain/awr044

McEvoy, L.K., Holland, D., Hagler, D.J., Fennema-Notestine, C., Brewer, J.B., Dale, A.M., Alzheimer's Disease Neuroimaging Initiative and Whitcher, B. 2011. Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis. Radiology. 259 (3), pp. 834-843. https://doi.org/10.1148/radiol.11101975

Kauwe, J.S., Cruchaga, C., Karch, C.M., Sadle, B., Lee, M., Mayo, K., Latu, W., Su'a, M., Fagan, A.M., Holtzman, D.M., Morris, J.C., Alzheimer's Disease Neuroimaging Initiative, Goate, A.M. and Whitcher, B. 2011. Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. PLoS ONE. 6 (2) e15918. https://doi.org/10.1371/journal.pone.0015918

Ahmad, F., Coleman, S.K., Kaila, K. and Blaesse, P. 2011. Cold-adapted protease enables quantitation of surface proteins in the absence of membrane trafficking. BioTechniques. 50 (4), pp. 255-257. https://doi.org/10.2144/000113651

Pathak, P., Naik, P.K., Sengupta, D., Singh, S.K. and Tandon, C. 2011. Mode of interaction of calcium oxalate crystal with human phosphate cytidylyltransferase 1: a novel inhibitor purified from human renal stone matrix. Journal of Biomedical Science and Engineering. 4 (9), pp. 591-598. https://doi.org/10.4236/jbise.2011.49075

Corpas, M., Doumbia, S., Gascuel, O. and Mulder, N. 2011. Bamako 2009 Conference on the Bioinformatics of Infectious Diseases. Infection, Genetics and Evolution. 11 (4), pp. 695-697. https://doi.org/10.1016/j.meegid.2011.02.012

Jimenez, R.C., Salazar, G.A., Gel, B., Dopazo, J., Mulder, N. and Corpas, M. 2011. myKaryoView: a light-weight client for visualization of genomic data. PLoS ONE. 6 (10) e26345. https://doi.org/10.1371/journal.pone.0026345

Pagnamenta, A.T., Holt, R., Yusuf, M., Pinto, D., Wing, K., Betancur, C., Scherer, S.W., Volpi, E.V. and Monaco, A.P. 2011. A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3. Journal of Neurodevelopmental Disorders. 3, pp. 124-131. https://doi.org/10.1007/s11689-011-9076-5

Lipinski, D.M., Yusuf, M., Barnard, A.R., Damant, C., Charbel Issa, P., Singh, M.S., Lee, E., Davies, W.L., Volpi, E.V. and MacLaren R.E. 2011. Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy. Investigative Ophthalmology & Visual Science. 52 (9), pp. 6617-6623. https://doi.org/10.1167/iovs.11-7932

Praper, T., Sonnen, A.F., Kladnik, A., Andrighetti, A.O., Viero, G., Morris, K.J., Volpi, E.V., Lunelli, L., Dalla Serra, M., Froelich, C.J., Gilbert, R.J. and Anderluh, G. 2011. Perforin activity at membranes leads to invaginations and vesicle formation. Proceedings of the National Academy of Sciences of the United States of America. 108 (52). https://doi.org/10.1073/pnas.1107473108

Wilson. M., O Hanlon, R., Prasad, S., Oxborough, D., Godfrey, R., Alpendurada, F., Smith, G., Wong, J., Basavarajaiah, S., Sharma, S., Nevill, A., Gaze, D.C., George, K. and Whyte, G. 2011. Biological markers of cardiac damage are not related to measures of cardiac systolic and diastolic function using cardiovascular magnetic resonance and echocardiography following an acute bout of prolonged endurance exercise. British Journal of Sports Medicine. 45, pp. 780-784. https://doi.org/10.1136/bjsm.2009.064089

Damman, K., Chuen, M. J., MacFadyen, R., Gregory, Y. H., Lip, M. D., Gaze, D.C., Collinson, P.O., Hillege, H. L., Oeveren, W van, Voors, A. A. and Veldhuisen, D. J. van 2011. Volume status and diuretic therapy in systolic heart failure and the detection of early abnormalities in renal and tubular function. Journal of the American College of Cardiology. 57 (22), pp. 2242-2243. https://doi.org/10.1016/j.jacc.2010.10.065

Gaze, D.C. 2011. The perils pitfalls and opportunities of using high sensitivity cardiac troponin. Current Medicinal Chemistry. 18 (23), pp. 3442-3445(4). https://doi.org/10.2174/092986711796642571

Williams, K., George, K., Hulton, A., Godfrey, R., Lahart, I., Wilson, M.G., Charlesworth, S., Warburton, D., Gaze, D.C. and Whyte, G. 2011. A unique case series of novel biomarkers of cardiac damage in cyclists completing the 4800 km Race Across America (RAAM). Current Medicinal Chemistry. 18 (23), pp. 3446-3451. https://doi.org/10.2174/092986711796642616

Nie, J., George, K.P., Tong, T.K., Gaze, D.C., Tian, Y., Lin, H. and Shi, Q. 2011. The influence of a half-marathon upon cardiac troponin T release in adolescent runners. Current Medicinal Chemistry. 18 (23), pp. 3452-3456. https://doi.org/10.2174/092986711796642625

Howatson, G., Goodall, S., Hill, J., Brouner, J., Gaze, D.C., McHugh, J and Shave, R. 2011. Antioxidant supplementation does not attenuate exercise-induced cardiac troponin release. International Journal of Cardiology. 152 (1), pp. 101-102. https://doi.org/10.1016/j.ijcard.2011.07.006

Collinson, P.O., Heung, Y.M., Gaze, D.C., Boa, F., Senior, R., Christenson, R. and Apple, F.S. 2011. Influence of Population selection on the 99th percentile reference value for cardiac troponin assays. Clinical Chemistry. 58 (1), pp. 219-225. https://doi.org/10.1373/clinchem.2011.171082

Li, J., Kent, D.G., Chen, E. and Green, A.R. 2011. Mouse models of myeloproliferative Neoplasms: JAK of all grades. (Review). Disease Models and Mechanisms. 4, pp. 311-317. https://doi.org/10.1242/dmm.006817

Adaikalakoteswari, A., Tripathi, G. and Saravanan, P. 2011. Low B12 and High Folate: Novel Mechanism of Higher Insulin Resistance in Human Adipocytes. 7th World Congress on Developmental Origins of Health and Disease. Portland, Oregon, USA 18 - 21 Sep 2011 Cambridge University Press. https://doi.org/10.1017/S2040174411000481

Adaikalakoteswari, A., Moore, J., McTernan, P.G., Kumar, S., Saravanan, P. and Tripathi, G. 2011. Low B12 and high folate: a novel regulator of cholesterol biosynthesis in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

McGee, K.C., Harte, A.L., Oscarsson, J., Brown, A., Fernandes Da Silva, N., McCarthy, C., Clapham, J., Kumar, S., Tripathi, G. and McTernan, P.G. 2011. Mitochondrial bioenergetics changes are induced by metabolic endotoxinaemia contributing to mitochondrial stress and dysfunction in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Kumsaiyai, W., Harte, A.L., Saravanan, P., Kyrou, I., Aldaghri, N., Kumar, S., Tripathi, G. and McTernan, P.G. 2011. Adiposity and diabetic status influences PLA2 isoforms in human abdominal subcutaneous and omental adipose tissue. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

McCarthy, C., Adaikalakoteswari, A., Moore, J., Brown, A.L., Brown, A., McTernan, P.G., Saravanan, P. and Tripathi, G. 2011. Folate and vitamin B12 imbalance induces endoplasmic reticulum stress in human adipocytes. 47th Annual Meeting of the EASD. Lisbon 12 - 16 Sep 2011 Springer. https://doi.org/10.1007/s00125-011-2276-4

Lewis, J. and Dodge, J. 2011. Phylum Dinophyta (Dinoflagellates). in: John, D., Whitton, B. and Brook, A. (ed.) The Freshwater Algal Flora of the British Isles. Second Edition Cambridge University Press. pp. 250-274

Youssef-Elabd, E.M., McGee, K.C., Tripathi, G., Abdalla, M.S., Sharada, H.M., Ashraf, E.A., Amin, I., Ceriello, A., O'Hare, J.P., Kumar, S., McTernan, P.G. and Harte, A.L. 2011. Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro. Journal of Nutritional Biochemistry. 23 (1), pp. 39-50. https://doi.org/10.1016/j.jnutbio.2010.11.003

Schisano, B., Tripathi, G., McGee, K., McTernan, P.G. and Ceriello, A. 2011. Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells. Diabetologia. 54 (5), pp. 1219-1226. https://doi.org/10.1007/s00125-011-2049-0

McGee, K.C., Harte, A.L., da Silva, N.F., Al-Daghri, N., Creely, S.J., Kusminski, C.M., Tripathi, G., Levick, P.L., Khanolkar, M., Evans, M., Chittari, M.V., Patel, V., Kumar, S. and McTernan, P.G. 2011. Visfatin Is Regulated by Rosiglitazone in Type 2 Diabetes Mellitus and Influenced by NFκB and JNK in Human Abdominal Subcutaneous Adipocytes. PLoS ONE. 6 (6) e20287. https://doi.org/10.1371/journal.pone.0020287

Gayà‐Vidal, M., Moral, P., Saenz‐Ruales, N., Gerbault, P., Tonasso, L., Villena, M., Vasquez, R., Bravi, C.M. and Dugoujon, J.M. 2011. mtDNA and Y‐chromosome diversity in Aymaras and Quechuas from Bolivia: Different stories and special genetic traits of the Andean Altiplano populations. American Journal of Physical Anthropology. 145 (2), pp. 215-230. https://doi.org/10.1002/ajpa.21487

Gerbault, P., Liebert, A., Itan, Y., Powell, A., Currat, M., Burger, J., Swallow, D. and Thomas, M.G. 2011. Evolution of lactase persistence: an example of human niche construction. Philosophical Transactions of the Royal Society B: Biological Sciences. 366 (1566), pp. 863-877. https://doi.org/10.1098/rstb.2010.0268

Raheem, S., Botting, Nigel P., Williamson, G. and Barron, D. 2011. Total synthesis of 3,5-O-dicaffeoylquinic acid and its derivatives. Tetrahedron Letters. 52 (52), p. 7175. https://doi.org/10.1016/j.tetlet.2011.10.127

McCormick, A.L., Parry, C.M., Crombe, A., Goodall, R.L., Gupta, R.K., Kaleebu, P., Kityo, C., Chirara, M., Towers, G.J. and Pillay, D. 2011. Impact of the N348I Mutation in HIV-1 Reverse Transcriptase on Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Non-Subtype B HIV-1. Antimicrobial Agents and Chemotherapy. 55 (4), pp. 1806-1809. https://doi.org/10.1128/AAC.01197-10