Life Sciences

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HeadProf Alistair Mathie
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Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages

Journal article

Fuchs, Marc-Aurel, Ryan, Louise A., Chambers, Emma L., Moore, Catherine M., Fairweather, Ian, Trudgett, Alan, Timson, David J., Brennan, Gerry P. and Hoey, Elizabeth M. 2013. Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages. International Journal for Parasitology. 43 (14), pp. 1133-1139. https://doi.org/10.1016/j.ijpara.2013.08.007

Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells.

Journal article

Anderson, A., Laurenson-Schafer, H., Partridge, F.A., Hodgkin, J. and McMullan, R. 2013. Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells. PLOS Pathogens. 9 (12) e1003787. https://doi.org/10.1371/journal.ppat.1003787

Rnd3 induces stress fibres in endothelial cells through RhoB.

Journal article

Gottesbühren, U., Garg, R., Riou, P., McColl, B., Brayson, D. and Ridley, A.J. 2013. Rnd3 induces stress fibres in endothelial cells through RhoB. Biology Open. 2 (2), pp. 210-216. https://doi.org/10.1242/bio.20123574

Development and Remodeling of the Vertebrate Blood-Gas Barrier

Journal article

Anagnostopoulou, A., Makanya and Valentin Djonov 2013. Development and Remodeling of the Vertebrate Blood-Gas Barrier. BioMed Research International. 2013. https://doi.org/10.1155/2013/101597

A quantitative study of white matter hypomyelination and oligodendroglial maturation in focal cortical dysplasia type II

Journal article

Shepherd, C., Liu, J., Goc, J., Martinian, L., Jacques, T.S., Sisodiya, S.M., Thom, M. and Liu, J.Y.W. 2013. A quantitative study of white matter hypomyelination and oligodendroglial maturation in focal cortical dysplasia type II. Epilepsia. 54 (5), pp. 898-908. https://doi.org/10.1111/epi.12143

P-glycoprotein expression and function in patients with temporal lobe epilepsy: A case-control study

Journal article

Feldmann, M., Asselin, M.-C., Wang, S., McMahon, A., Anton-Rodriguez, J., Walker, M., Symms, M., Brown, G., Hinz, R., Matthews, J., Bauer, M., Langer, O., Thom, M., Jones, T., Vollmar, C., Duncan, J.S., Sisodiya, S.M., Koepp, M.J. and Liu, J.Y.W. 2013. P-glycoprotein expression and function in patients with temporal lobe epilepsy: A case-control study. The Lancet Neurology. 12 (8), pp. 777-785. https://doi.org/10.1016/s1474-4422(13)70109-1

MAPPED study design: A 6month randomised controlled study to evaluate the effect of dutasteride on prostate cancer volume using magnetic resonance imaging

Journal article

Robertson, N.L., Moore, C.M., Ambler, G., Bott, S.R.J., Freeman, A., Gambarota, G., Jameson, C., Mitra, A.V., Whitcher, B., Winkler, M., Kirkham, A., Allen, C. and Emberton, M. 2013. MAPPED study design: A 6month randomised controlled study to evaluate the effect of dutasteride on prostate cancer volume using magnetic resonance imaging. Contemporary Clinical Trials. 34 (1), pp. 80-89. https://doi.org/10.1016/j.cct.2012.10.003

Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease

Journal article

Douaud, G., Menke, R.A.L., Gass, A., Monsch, A.U., Rao, A., Whitcher, B., Zamboni, G., Matthews, P.M., Sollberger, M. and Smith, S. 2013. Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease. Journal of Neuroscience. 33 (5), pp. 2147-2155. https://doi.org/10.1523/jneurosci.4437-12.2013

Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor

Journal article

Sengupta, D., Sood, M., Vijayvargia, P., Hota, S. and Naik, P.K. 2013. Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor. Bioinformation. 9 (11), pp. 555-559. https://doi.org/10.6026/97320630009555

Design of dimensional model for clinical data storage and analysis

Journal article

Sengupta, D., Arora, P., Pant, S. and Naik, P.K. 2013. Design of dimensional model for clinical data storage and analysis. Applied Medical Informatics. 32 (2), pp. 47-53.

SN algorithm: analysis of temporal clinical data for mining periodic patterns and impending augury

Journal article

Sengupta, D. and Naik, P.K. 2013. SN algorithm: analysis of temporal clinical data for mining periodic patterns and impending augury. Journal of Clinical Bioinformatics. 3 24. https://doi.org/10.1186/2043-9113-3-24

The Young PI Buzz: Learning from the Organizers of the Junior Principal Investigator Meeting at ISMB-ECCB 2013

Journal article

de Ridder, J., Bromberg, Y., Michaut, M., Satagopam, V.P., Corpas, M., Macintyre, G. and Alexandrov, T. 2013. The Young PI Buzz: Learning from the Organizers of the Junior Principal Investigator Meeting at ISMB-ECCB 2013. PLOS Computational Biology. https://doi.org/10.1371/journal.pcbi.1003350

Bioinformatics workflows and web services in systems biology made easy for experimentalists

Book chapter

Jimenez, R.C. and Corpas, M. 2013. Bioinformatics workflows and web services in systems biology made easy for experimentalists. in: Schneider, M.V. (ed.) In Silico Systems Biology Humana Press. pp. 299-310

BioJS: an open source JavaScript framework for biological data visualization

Journal article

Gómez, J., García, L.J., Salazar, G.A., Villaveces, J., Gore, S., García, A., Martín, M.J., Launay, G., Alcántara, R., Del-Toro, N., Dumousseau, M., Orchard, S., Velankar, S., Hermjakob, H., Zong, C., Ping, P., Corpas, M. and Jiménez, R.C. 2013. BioJS: an open source JavaScript framework for biological data visualization. Bioinformatics. 29 (8), pp. 1103-1104. https://doi.org/10.1093/bioinformatics/btt100

iAnn: an event sharing platform for the life sciences

Journal article

Jimenez, R.C., Albar, J.P., Bhak, J., Blatter, M.C., Blicher, T., Brazas, M.D., Brooksbank, C., Budd, A., De Las Rivas, J., Dreyer, J., van Driel, M.A., Dunn, M.J., Fernandes, P.L., van Gelder, C.W., Hermjakob, H., Ioannidis, V., Judge, D.P., Kahlem, P., Korpelainen, E., Kraus, H.J., Loveland, J., Mayer, C., McDowall, J., Moran, F., Mulder, N., Nyronen, T., Rother, K., Salazar, G.A., Schneider, R., Via, A., Villaveces, J.M., Yu, P., Schneider, M.V., Attwood, T.K. and Corpas, M. 2013. iAnn: an event sharing platform for the life sciences. Bioinformatics. 29 (15), pp. 1919-1921. https://doi.org/10.1093/bioinformatics/btt306

Crowdsourcing the corpasome

Article

Corpas M 2013. Crowdsourcing the corpasome. Source Code for Biology and Medicine. 8 13. https://doi.org/10.1186/1751-0473-8-13

Comparative study of artificial chromosome centromeres in human and murine cells

Journal article

Moralli, D., Jefferson, A., Volpi, E. and Larin Monaco, Z. 2013. Comparative study of artificial chromosome centromeres in human and murine cells. European Journal of Human Genetics. 21, pp. 948-956. https://doi.org/10.1038/ejhg.2012.296

Robotic injection of zebrafish embryos for high-throughput screening in disease models

Journal article

Spaink, Herman P., Cui, Chao, Wiweger, Malgorzata I., Jansen, Hans J., Veneman, Wouter J., Marin-Juez, Ruben, de Sonneville, Jan, Ordas, Anita, Torraca, V., van der Ent, Wietske, Leenders, William P., Meijer, Annemarie H., Snaar-Jagalska, B. Ewa and Dirks, Ron P. 2013. Robotic injection of zebrafish embryos for high-throughput screening in disease models. Methods. 62 (3), pp. 246-254. https://doi.org/10.1016/j.ymeth.2013.06.002

Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation

Journal article

Jonas N. Pedersen, Rodolphe Marie, David L.V. Bauer, Kristian H. Rasmussen, Mohammed Yusuf, Emanuela V. Volpi, Anders Kristensen, Kalim U. Mir and Henrik Flyvbjerg 2013. Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation. Biophysical Journal. 104 (2, Supplement 1,), p. 175A. https://doi.org/10.1016/j.bpj.2012.11.986

How women use and experience western herbal practice for distress: Implications for health care and self-management approaches

Journal article

Yates, A., Green, J., Whitehouse, J. and Ridge, Damien T. 2013. How women use and experience western herbal practice for distress: Implications for health care and self-management approaches. European Journal of Integrative Medicine. 5 (6), pp. 579-580. https://doi.org/10.1016/j.eujim.2013.08.019

Self-assembling nanomaterials: Monitoring the formation of amyloid fibrils, with a focus on small-angle x-ray scattering

Book chapter

Sawyer, E.B. and Gras, S.L. 2013. Self-assembling nanomaterials: Monitoring the formation of amyloid fibrils, with a focus on small-angle x-ray scattering. in: Gerrard, J.A. (ed.) Protein Nanotechnology Humana Press.

Advanced age influences the dynamic changes in circulating C-reactive protein following injury

Journal article

Pinato, D.J., Bains, J., Irkulla, S., Pomroy, J., Ujam, B., Gaze, D.C. and Mendall, M. 2013. Advanced age influences the dynamic changes in circulating C-reactive protein following injury. Journal of Clinical Pathology. 66 (8). https://doi.org/10.1136/jclinpath-2012-201374

A prospective, randomized, placebo-controlled, double-blind, multicenter study of the effects of irbesartan on aortic dilatation in Marfan syndrome (AIMS trial): study protocol.

Journal article

Mullen, M J, Flather, M. D, Jin, X. Y., Newman, W. G., Erdem, G., Gaze, D.C., Valencia, O., Banya, W., Foley, C. E. and Child, A. 2013. A prospective, randomized, placebo-controlled, double-blind, multicenter study of the effects of irbesartan on aortic dilatation in Marfan syndrome (AIMS trial): study protocol. Trials. 14 408. https://doi.org/10.1186/1745-6215-14-408

The association between cortisol response to mental stress and high-sensitivity cardiac troponin T plasma concentration in healthy adults

Journal article

Lazzarino, A., Hamer, M., Gaze, D.C., Collinson, P.O. and Steptoe, A. 2013. The association between cortisol response to mental stress and high-sensitivity cardiac troponin T plasma concentration in healthy adults. Journal of the American College of Cardiology. 62 (18), pp. 1694-1701. https://doi.org/10.1016/j.jacc.2013.05.070

A gripping problem: cardiac biomarkers in patients with intermittent claudication

Journal article

Gaze, D.C. 2013. A gripping problem: cardiac biomarkers in patients with intermittent claudication. Biomarkers in Medicine. 7 (3), p. 399. https://doi.org/10.2217/bmm.13.40

Clot Disruption: the role of the D-dimer in testing for deep vein thrombosis

Journal article

Gaze, D. 2013. Clot Disruption: the role of the D-dimer in testing for deep vein thrombosis. Biomarkers in Medicine. 7 (3), pp. 400-401. https://doi.org/10.2217/bmm.13.40

A sticky situation: fibrinogen and coronary artery disease

Journal article

Gaze, D. 2013. A sticky situation: fibrinogen and coronary artery disease. Biomarkers in Medicine. 7 (3), pp. 399-400. https://doi.org/10.2217/bmm.13.40

Randomised Assessment of Treatment using Panel Assay of Cardiac markers - Contemporary Biomarker Evaluation (RATPAC CBE)

Journal article

Collinson, P., Gaze, D.C., Thokala, K. and Goodacre, S. 2013. Randomised Assessment of Treatment using Panel Assay of Cardiac markers - Contemporary Biomarker Evaluation (RATPAC CBE). Health Technology Assessment. 17 (15). https://doi.org/10.3310/hta17150

Cardiac electromechanical delay is increased during recovery from 40 km cycling but is not mediated by exercise intensity

Journal article

Chan‐Dewar, F., Gregson, W., Whyte, G., King, J., Gaze, D.C., Carranza‐García, L.E., Legaz‐Arrese, A. and George, K. 2013. Cardiac electromechanical delay is increased during recovery from 40 km cycling but is not mediated by exercise intensity. The Scandinavian Journal of Medicine & Science in Sports . 23 (2), pp. 224-231. https://doi.org/10.1111/j.1600-0838.2011.01376.x

Clonal analysis reveal associations of JAK2V617F homozygosity with hematological features, age and gender in PV and ET

Journal article

Godfrey, A.L., Chen, E., Pagano, F., Silber, Y., Campbell, P.J. and Green, A.R. 2013. Clonal analysis reveal associations of JAK2V617F homozygosity with hematological features, age and gender in PV and ET. Haematologica. 98, pp. 718-721. https://doi.org/10.3324/haematol.2012.079129

Do the effects of high intensity 40 km cycling upon left ventricular function and cardiac biomarker during recovery vary with time of day?

Journal article

Chan-Dewar, F., Gregson, W., Whyte, G., Gaze, D.C., Waterhouse, J., Wen, J. and George, K. 2013. Do the effects of high intensity 40 km cycling upon left ventricular function and cardiac biomarker during recovery vary with time of day? Journal of Sports Sciences. 31 (4), pp. 414-423. https://doi.org/10.1080/02640414.2012.735369

Abdominal adiposity is the main determinant of the C-reactive response to injury in subjects undergoing inguinal hernia repair

Journal article

Irkulla, S., Ujam, B., Gaze, D.C., Kumar, D. and Mendall, M. 2013. Abdominal adiposity is the main determinant of the C-reactive response to injury in subjects undergoing inguinal hernia repair. Journal of Inflammation. 10 (1), p. 5 5. https://doi.org/10.1186/1476-9255-10-5

Biomarkers of Cardiac Ischemia

Book chapter

Gaze, D.C. 2013. Biomarkers of Cardiac Ischemia. in: Gaze, D.C. (ed.) Ischemic Heart Disease Croatia InTech Publishing. pp. 91-122

Introduction to Ischemic Heart Disease

Book chapter

Gaze, D.C. 2013. Introduction to Ischemic Heart Disease. in: Gaze, D.C. (ed.) Ischemic Heart Disease Croatia InTech Publishing. pp. 1-14

Ischemic Heart Disease

Book

Gaze, D.C. (ed.) 2013. Ischemic Heart Disease. Croatia InTech Publishing.

Fluorescence Characterization of Clinically-Important Bacteria

Journal article

Dartnell, L.R., Roberts, T.A., Moore, G., Ward, J.M. and Muller, J-P. 2013. Fluorescence Characterization of Clinically-Important Bacteria. PLoS ONE. 8 (9) e75270. https://doi.org/10.1371/journal.pone.0075270

Written medical discharge communication from an acute stroke service: a project to improve content through development of a structured stroke-specific template

Journal article

Makela, P., Haynes, C., Holt, K. and Kar, A. 2013. Written medical discharge communication from an acute stroke service: a project to improve content through development of a structured stroke-specific template. BMJ Open Quality. :u202037.w1095. https://doi.org/10.1136/bmjquality.u202037.w1095

Macronutrient regulation of PYY and DPPIV in human intestinal epithelial cells

Conference paper

Zariwala, M., Kosicka, A. and Renshaw, D. 2013. Macronutrient regulation of PYY and DPPIV in human intestinal epithelial cells. ENDO 2013: The Endocrine Society’s 95th Annual Meeting. San Francisco, USA 15 - 18 Jun 2013

Preparation and Characterisation of Solid Lipid Particles for Oral Iron Delivery

Conference paper

Zariwala, M., Farnaud, S., Somavarapu, S. and Renshaw, D. 2013. Preparation and Characterisation of Solid Lipid Particles for Oral Iron Delivery. Fifth Congress of the International BioIron Society (IBIS), Biennial World Meeting. University College London 14 - 18 Apr 2013 Wiley. https://doi.org/10.1002/ajh.23453

Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms

Conference paper

Mehta, K., Patel, V., Busbridge, M., Renshaw, D., Zariwala, M., Evans, R. and Farnaud, S. 2013. Hepcidin transcription and peptide secretion are governed by different regulatory mechanisms. Fifth Congress of the International BioIron Society (IBIS), Biennial World Meeting. University College London 14 - 18 Apr 2013 Wiley. https://doi.org/10.1002/ajh.23453


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