A correlational analysis of COVID-19 incidence and mortality and urban determinants of vitamin D status across the London boroughs

Borna, M., Woloshynowych, M., Schiano-Phan, R., Volpi, E. and Usman, M. 2022. A correlational analysis of COVID-19 incidence and mortality and urban determinants of vitamin D status across the London boroughs. Scientific Reports. 12 (1) 11741. https://doi.org/10.1038/s41598-022-15664-y

TitleA correlational analysis of COVID-19 incidence and mortality and urban determinants of vitamin D status across the London boroughs
TypeJournal article
AuthorsBorna, M., Woloshynowych, M., Schiano-Phan, R., Volpi, E. and Usman, M.
Abstract

One of the biggest challenges of the COVID-19 pandemic is the heterogeneity in disease severity exhibited amongst patients. Among multiple factors, latest studies suggest vitamin D deficiency and pre-existing health conditions to be major contributors to death from COVID-19. It is known that certain urban form attributes can impact sun exposure and vitamin D synthesis. Also, long-term exposure to air pollution can play an independent role in vitamin D deficiency. We conducted a correlational analysis of urban form and air quality in relation to the demographics and COVID-19 incidence and mortality across 32 London boroughs between March 2020 and January 2021. We found total population, number of residents of Asian ethnicity, 4-year average PM10 levels and road length to be positively correlated with COVID-19 cases and deaths. We also found percentage of households with access to total open space to be negatively correlated with COVID-19 deaths. Our findings link COVID-19 incidence and mortality across London with environmental variables linked to vitamin D status. Our study is entirely based on publicly available data and provides a reference framework for further research as more data are gathered and the syndemic dimension of COVID-19 becomes increasingly relevant in connection to health inequalities within large urban areas.

KeywordsAir Pollutants - analysis
COVID-19 - epidemiology
Air Pollution - adverse effects - analysis
Vitamin D - analysis
Vitamins - analysis
Humans
London - epidemiology
Pandemics
Incidence
Vitamin D Deficiency - epidemiology
Article number11741
JournalScientific Reports
Journal citation12 (1)
ISSN2045-2322
Year2022
PublisherNature Publishing Group
Publisher's version
License
CC BY 4.0
File Access Level
Open (open metadata and files)
Digital Object Identifier (DOI)https://doi.org/10.1038/s41598-022-15664-y
PubMed ID35817805
Web address (URL)http://dx.doi.org/10.1038/s41598-022-15664-y
Publication datesJul 2022
Published online11 Jul 2022
PublishedJul 2022

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Babbs, C., Lloyd, D., Pagnamenta, A.T., Twiggs, S.R., Green, J., McGowan, S.J., Mirza, G., Naples, R., Sharma, V.P., Volpi, E., Buckle, V.J., Wall, S.A., Knight SJ; International Molecular Genetic Study of Autism Consortium (IMGSAC), Parr, J.R. and Wilkie, A.O. 2014. De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder. Journal of Medical Genetics. 51 (11), pp. 737-747. https://doi.org/10.1136/jmedgenet-2014-102582

Cool city: cooling strategies for the urban context
Schiano-Phan, R. 2014. Cool city: cooling strategies for the urban context. in: Rodriguez, J. and Yannas, S. (ed.) Collective housing and sustainability Madrid ETSAM.

A multicentre observational study to evaluate a new tool to assess emergency physicians' non-technical skills
Flowerdew, L., Gaunt, A., Spedding, J., Bhargava, A., Brown, R., Vincent, C. and Woloshynowych, M. 2013. A multicentre observational study to evaluate a new tool to assess emergency physicians' non-technical skills. Emergency Medicine Journal. 30 (6), pp. 437-443. https://doi.org/10.1136/emermed-2012-201237

Comparative study of artificial chromosome centromeres in human and murine cells
Moralli, D., Jefferson, A., Volpi, E. and Larin Monaco, Z. 2013. Comparative study of artificial chromosome centromeres in human and murine cells. European Journal of Human Genetics. 21, pp. 948-956. https://doi.org/10.1038/ejhg.2012.296

Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation
Jonas N. Pedersen, Rodolphe Marie, David L.V. Bauer, Kristian H. Rasmussen, Mohammed Yusuf, Emanuela V. Volpi, Anders Kristensen, Kalim U. Mir and Henrik Flyvbjerg 2013. Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation. Biophysical Journal. 104 (2, Supplement 1,), p. 175A. https://doi.org/10.1016/j.bpj.2012.11.986

Chromosomes and nuclear organisation in ICF syndrome
Volpi, E. 2013. Chromosomes and nuclear organisation in ICF syndrome. in: Yurov, Y.B., Vorsanova, S.G. and Iourov, I.Y. (ed.) Human interphase chromosomes: biomedical aspects New York Springer. pp. 107-121

Integrated view of genome structure and sequence of a single DNA molecule in a nanofluidic device.
Marie, R., Pedersen, J.N., Bauer, D.L., Rasmussen, K.H., Yusuf, M., Volpi, E., Flyvbjerg, H., Kristensen, A. and Mir, K.U. 2013. Integrated view of genome structure and sequence of a single DNA molecule in a nanofluidic device. Proceedings of the National Academy of Sciences of the United States of America. 110 (13), pp. 4893-4898. https://doi.org/10.1073/pnas.1214570110

Comprehensive cytogenomic profile of the in vitro neuronal model SH-SY5Y
Yusuf, M., Leung, K., Morris, K.J. and Volpi, E. 2013. Comprehensive cytogenomic profile of the in vitro neuronal model SH-SY5Y. Neurogenetics. 14 (1), pp. 63-70. https://doi.org/10.1007/s10048-012-0350-9

Teams under pressure in the emergency department: an interview study
Flowerdew, L., Brown, R., Vincent, C. and Woloshynowych, M. 2012. Teams under pressure in the emergency department: an interview study. Emergency Medicine Journal. 29 e2. https://doi.org/10.1136/emermed-2011-200084

Identifying Nontechnical Skills Associated With Safety in the Emergency Department: A Scoping Review of the Literature
Flowerdew, L., Brown, R., Vincent, C. and Woloshynowych, M. 2012. Identifying Nontechnical Skills Associated With Safety in the Emergency Department: A Scoping Review of the Literature. Annals of Emergency Medicine. 59 (5), pp. 386-395. https://doi.org/10.1016/j.annemergmed.2011.11.021

Development and Validation of a Tool to Assess Emergency Physicians' Nontechnical Skills
Flowerdew, L., Brown, R., Vincent, C. and Woloshynowych, M. 2012. Development and Validation of a Tool to Assess Emergency Physicians' Nontechnical Skills. Annals of Emergency Medicine. 59 (5), pp. 376-385. https://doi.org/10.1016/j.annemergmed.2011.11.022

Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition
De Colibus, L., Sonnen, A.F.-P., Morris, K.J., Siebert, C.A., Abrusci, P., Plitzko, J., Hodnik, V., Leippe, M., Volpi, E., Anderluh, G. and Gilbert, R.J.C. 2012. Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition. Structure. 20 (9), pp. P1498-1507. https://doi.org/10.1016/j.str.2012.06.011

The ABC of Handover: Impact on shift handover in the Emergency Department
Farhan, M., Brown, R., Vincent, C. and Woloshynowych, M. 2012. The ABC of Handover: Impact on shift handover in the Emergency Department. Emergency Medicine Journal. 19, pp. 947-953. https://doi.org/10.1136/emermed-2011-200201

The ABC of handover: a qualitative study to develop a new tool for handover in the emergency department.
Farhan, M., Brown, R., Woloshynowych, M. and Vincent, C. 2012. The ABC of handover: a qualitative study to develop a new tool for handover in the emergency department. Emergency Medicine Journal. 29, pp. 941-946. https://doi.org/10.1136/emermed-2011-200199

Post-occupancy evaluation of non-domestic buildings using passive downdraught evaporative cooling in south-west USA
Schiano-Phan, R. 2012. Post-occupancy evaluation of non-domestic buildings using passive downdraught evaporative cooling in south-west USA. Architectural Science Review. 55 (4), pp. 320-340. https://doi.org/10.1080/00038628.2012.725535

High-resolution fish on DNA fibers for low-copy repeats genome architecture studies.
Molina, O., Blanco, J., Anton, E., Vidal, F. and Volpi, E.V. 2012. High-resolution fish on DNA fibers for low-copy repeats genome architecture studies. Genomics. 100 (6), pp. 380-386. https://doi.org/10.1016/j.ygeno.2012.08.007

Patient safety factors in children dying in a paediatric intensive care unit (PICU): a case notes review study
Monroe, K., Wang, D., Vincent, C., Woloshynowych, M., Neale, G. and Inwald, D.P. 2011. Patient safety factors in children dying in a paediatric intensive care unit (PICU): a case notes review study. BMJ Quality and Safety. 20, pp. 863-868. https://doi.org/10.1136/bmjqs.2010.048504

A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3
Pagnamenta, A.T., Holt, R., Yusuf, M., Pinto, D., Wing, K., Betancur, C., Scherer, S.W., Volpi, E.V. and Monaco, A.P. 2011. A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3. Journal of Neurodevelopmental Disorders. 3, pp. 124-131. https://doi.org/10.1007/s11689-011-9076-5

Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy.
Lipinski, D.M., Yusuf, M., Barnard, A.R., Damant, C., Charbel Issa, P., Singh, M.S., Lee, E., Davies, W.L., Volpi, E.V. and MacLaren R.E. 2011. Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy. Investigative Ophthalmology & Visual Science. 52 (9), pp. 6617-6623. https://doi.org/10.1167/iovs.11-7932

Perforin activity at membranes leads to invaginations and vesicle formation
Praper, T., Sonnen, A.F., Kladnik, A., Andrighetti, A.O., Viero, G., Morris, K.J., Volpi, E.V., Lunelli, L., Dalla Serra, M., Froelich, C.J., Gilbert, R.J. and Anderluh, G. 2011. Perforin activity at membranes leads to invaginations and vesicle formation. Proceedings of the National Academy of Sciences of the United States of America. 108 (52). https://doi.org/10.1073/pnas.1107473108

Stress Management Training for Surgeons - a randomised controlled intervention study
Wetzel, C.M., George, A., Hanna, G.B., Athanasiou, T., Black, S.A., Kneebone, R.L., Nestel, D. and Woloshynowych, M. 2011. Stress Management Training for Surgeons - a randomised controlled intervention study. Annals of Surgery. 253 (3), pp. 488-494. https://doi.org/10.1097/SLA.0b013e318209a594

Combining M-FISH and Quantum Dot technology for fast chromosomal assignment of transgenic insertions
Yusuf, M., Bauer, D.L.V., Lipinski, D.M., MacLaren, R.E., Wade-Martins, R., Mir, K.U. and Volpi, E. 2011. Combining M-FISH and Quantum Dot technology for fast chromosomal assignment of transgenic insertions. BMC Biotechnology. 11, pp. 121-131. https://doi.org/10.1186/1472-6750-11-121

An improved technique for chromosomal analysis of human ES and iPS cells.
Moralli, D., Yusuf, M., Mandegar, M.A., Khoja, S., Monaco, Z.L. and Volpi, E.V. 2011. An improved technique for chromosomal analysis of human ES and iPS cells. Stem Cell Reviews. 7 (2), pp. 471-477. https://doi.org/10.1007/s12015-010-9224-4

Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells
Mandegar, M.A., Moralli, D., Khoja, S., Cowley, S., Chan, D.Y.L., Yusuf, M., Mukherjee, S., Blundell, M.P., Volpi, E., Thrasher, A.J., James, W. and Monaco, Z.L. 2011. Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells. Human Molecular Genetics. 20 (15), pp. 2905-2913. https://doi.org/10.1093/hmg/ddr144

Environmental retrofit: Building integrated passive cooling in housing
Schiano-Phan, R. 2010. Environmental retrofit: Building integrated passive cooling in housing. Architectural Research Quarterly. 14 (2), pp. 139-151. https://doi.org/10.1017/s1359135510000758

Factors compromising safety in surgery: stressful events in the operating room
Arora, S., Hull, L., Tierney, T., Nestel, D., Woloshynowych, M., Darzi, A. and Kneebone, R. 2010. Factors compromising safety in surgery: stressful events in the operating room. The American Journal of Surgery. 199 (1), pp. P60-65. https://doi.org/10.1016/j.amjsurg.2009.07.036

The Imperial Stress Assessment Tool (ISAT): A feasible, reliable and valid approach to measuring stress in the Operating Room
Arora, S., Tierney, T., Sevdalis, N., Aggarwal, R., Woloshynowych, M., Nestel, D., Darzi, A. and Kneebone, R. 2010. The Imperial Stress Assessment Tool (ISAT): A feasible, reliable and valid approach to measuring stress in the Operating Room. World Journal of Surgery. 34, pp. 1756-1763. https://doi.org/10.1007/s00268-010-0559-4

The impact of stress on surgical performance: A systematic review of the literature
Arora, S., Sevdalis, N., Nestel, D., Woloshynowych, M., Darzi, A and Kneebone, R 2010. The impact of stress on surgical performance: A systematic review of the literature. Surgery. 147 (3), pp. 318-330. https://doi.org/10.1016/j.surg.2009.10.007

Reflective analysis of safety research in the hospital accident & emergency departments
Wears, R.L., Woloshynowych, M., Brown, R. and Vincent, C.A. 2010. Reflective analysis of safety research in the hospital accident & emergency departments. Applied Ergonomics. 41 (5), pp. 659-700. https://doi.org/10.1016/j.apergo.2009.12.006

Fluorescence in situ hybridization (FISH) for genomic investigations in rat
Jefferson, A. and Volpi, E.V. 2010. Fluorescence in situ hybridization (FISH) for genomic investigations in rat. in: Bridger, J. and Volpi, E. (ed.) Fluorescence in situ Hybridization (FISH). Methods in Molecular Biology (Methods and Protocols), vol 659 Humana Press. pp. 409-426

A novel three-dimensional culture system allows prolonged culture of functional human granulosa cells and mimics the ovarian environment.
Kossowska-Tomaszczuk, K., Pelczar, P., Güven, S., Kowalski, J., Volpi, E., De Geyter, C. and Scherberich, A. 2010. A novel three-dimensional culture system allows prolonged culture of functional human granulosa cells and mimics the ovarian environment. Tissue Engineering Part A. 16 (6), pp. 2063-73. https://doi.org/10.1089/ten.tea.2009.0684

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis.
Ashrafian, H., O'Flaherty, L., Adam, J., Steeples, V., Chung, Y.L., East, P., Vanharanta, S., Lehtonen, H., Nye, E., Hatipoglu, E., Miranda, M., Howarth, K., Shukla, D., Pollard, P.J. and Volpi, E. 2010. Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. Cancer Research. 70 (22), pp. 9153-9165. https://doi.org/10.1158/0008-5472.can-10-1949

The effect of stress and coping on surgical performance during simulations
Wetzel, C.M., Black, S.A., Hanna, G.B., Athanasiou, T., Kneebone, R.L., Nestel, D., Wolfe, J.H.N. and Woloshynowych, M. 2010. The effect of stress and coping on surgical performance during simulations . Annals of Surgery. 251 (1), pp. 171-176. https://doi.org/10.1097/SLA.0b013e3181b3b2be

Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome.
Jefferson, A., Colella, S., Moralli, D., Wilson, N., Yusuf, M., Gimelli, G., Ragoussis, J. and Volpi, E.V. 2010. Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome. PLoS ONE. 5 (6) e11364. https://doi.org/10.1371/journal.pone.0011364

Managing Intra-operative stress: What do surgeons want from a crisis training programme?
Arora, S., Sevdalis, N., Nestel, D., Tierney, T., Woloshynowych, M. and Kneebone, R. 2009. Managing Intra-operative stress: What do surgeons want from a crisis training programme? The American Journal of Surgery. 197 (4), pp. 537-543. https://doi.org/10.1016/j.amjsurg.2008.02.009

The Care Homes Use of Medicines Study: prevalence, causes and potential harm of medication errors in care homes for older people
Barber, N.D., Alldred, D.P., Raynor, D.K., Dickinson, R., Garfield, S., Jesson, B., Lim, R., Savage, I., Standage, C., Buckle, P., Carpenter, J., Franklin, B., Woloshynowych, M. and Zermansky, A.G. 2009. The Care Homes Use of Medicines Study: prevalence, causes and potential harm of medication errors in care homes for older people. BMJ Quality and Safety. 18, pp. 341-346. https://doi.org/10.1136/qshc.2009.034231

Methodological variability in detecting prescribing errors when evaluating computerised physician order entry
Dean Franklin, B., Birch, S., Savage, I., Wong, I., Woloshynowych, M., Jacklin, A. and Barber, N. 2009. Methodological variability in detecting prescribing errors when evaluating computerised physician order entry. Pharmacoepidemiology and Drug Safety. 18 (11), pp. 992-999. https://doi.org/10.1002/pds.1811

Mapping of partially overlapping de novo deletions across an autism susceptibility region (AUTS5) in two unrelated individuals affected by developmental delays with communication impairment.
Newbury, D.F., Warburton, P.C., Wilson, N., Bacchelli, E., Carone, S., International Molecular Genetic Study of Autism Consortium, Lamb, J.A., Maestrini, E., Monaco, A.P. and Volpi, E. 2009. Mapping of partially overlapping de novo deletions across an autism susceptibility region (AUTS5) in two unrelated individuals affected by developmental delays with communication impairment. American Journal of Medical Genetics Part A. 149A (4), pp. 588-597. https://doi.org/10.1002/ajmg.a.32704

HAC stability in murine cells is influenced by nuclear localization and chromatin organization.
Moralli, D., Chan, D.Y., Jefferson, A., Volpi, E.V. and Monaco, Z.L. 2009. HAC stability in murine cells is influenced by nuclear localization and chromatin organization. BMC Cell Biology. 10 18. https://doi.org/10.1186/1471-2121-10-18

Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection.
Sykes, N.H., Toma, C., Wilson, N., Volpi, E., Sousa, I., Pagnamenta, A.T., Tancredi, R., Battaglia, A., Maestrini, E., Bailey, A.J., Monaco, A.P. and International Molecular Genetic Study of Autism Consortium (IMGSAC) 2009. Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection. European Journal of Human Genetics. 17, pp. 1347-1353. https://doi.org/10.1038/ejhg.2009.47

Severe insulin resistance and intrauterine growth deficiency associated with haploin sufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism
Suliman, S.G., Stanik, J., McCulloch, L.J., Wilson, N., Edghill, E.L., Misovicova, N., Gasperikova, D., Sandrikova, V., Elliott, K.S., Barak, L., Ellard, S., Volpi, E.V., Klimes, I. and Gloyn, A.L. 2009. Severe insulin resistance and intrauterine growth deficiency associated with haploin sufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. Diabetes. 58 (12), pp. 2954-2961. https://doi.org/10.2337/db09-0787

Keep your cool with ceramics
Schiano-Phan, R. 2009. Keep your cool with ceramics. Clay Technology. Oct-Nov, pp. 10-12.

FISH glossary: an overview of the fluorescence in situ hybridization technique.
Volpi, E.V. and Bridger, J.M. 2008. FISH glossary: an overview of the fluorescence in situ hybridization technique. BioTechniques. 45 (4), pp. 385-409. https://doi.org/10.2144/000112811

Post occupancy evaluation of non-domestic buildings using downdraught cooling: Case studies in the US
Schiano-Phan, R. and Ford, B. 2008. Post occupancy evaluation of non-domestic buildings using downdraught cooling: Case studies in the US. Plea 2008: The 25th Conference on Passive & Low Energy Architecture. Dublin, Ireland 22-24 October 2008

Cooling without air-conditioning
Schiano-Phan, R. 2008. Cooling without air-conditioning. Intelligent Glass Solutions. 4, pp. 106-108.

The Passivhaus standard in European warm climates: design guidelines for comfortable low energy homes
Schiano-Phan, R., Ford, B. and Zhongcheng, D. 2007. The Passivhaus standard in European warm climates: design guidelines for comfortable low energy homes. Passive-On IEE project.

Continuity of care 2006: what have we learned since 2000 and what are policy imperatives now?
Freeman, G., Woloshynowych, M., Baker, R., Boulton, M., Guthrie, B., Car, J., Haggerty, J. and Tarrant, C. 2007. Continuity of care 2006: what have we learned since 2000 and what are policy imperatives now? NCCSDO.

Endothelial Nox2 overexpression potentiates vascular oxidative stress and hemodynamic response to angiotensin II: studies in endothelial-targeted Nox2 transgenic mice.
Bendall, J.K., Rinze, R., Adlam, D., Tatham, A.L., de Bono, J., Wilson, N., Volpi, E. and Channon, K.M. 2007. Endothelial Nox2 overexpression potentiates vascular oxidative stress and hemodynamic response to angiotensin II: studies in endothelial-targeted Nox2 transgenic mice. Circulation Research. 100, pp. 1016-1025. https://doi.org/10.1161/01.res.0000263381.83835.7b

Replication profile of PCDH11X and PCDH11Y, a gene pair located in the non-pseudoautosomal homologous region Xq21.3/Yp11.2.
Wilson, N.D., Ross, L.J., Close, J., Mott, R., Crow, T.J. and Volpi, E.V. 2007. Replication profile of PCDH11X and PCDH11Y, a gene pair located in the non-pseudoautosomal homologous region Xq21.3/Yp11.2. Chromosome Research. 15, pp. 485-498. https://doi.org/10.1007/s10577-007-1153-y

Search for neuroblastoma loci: characterization of tumor cell lines that could facilitate their positional cloning.
Romani, M., Muresu, R., Volpi, E.V., Rozzo, C., Marchi, J.M. and Casciano, I. 2007. Search for neuroblastoma loci: characterization of tumor cell lines that could facilitate their positional cloning. Journal of Neuro-oncology . 31, pp. 41-47. https://doi.org/10.1023/a:1005725112688

Communication Patterns in a UK Emergency Department
Woloshynowych, M., Davis, R., Brown, R. and Vincent, C. 2007. Communication Patterns in a UK Emergency Department. Annals of Emergency Medicine. 50 (4), pp. 407-413. https://doi.org/10.1016/j.annemergmed.2007.08.001

Patient safety and iatrogenesis
Woloshynowych, M. and Vincent, C. 2007. Patient safety and iatrogenesis. in: Ayers, S., Baum, A., McManus, C., Newman, S, Wallston, K., Weinman, J. and West, R. (ed.) Cambridge Handbook of Psychology, Health and Medicine. 2nd edition Cambridge University Press.

Incident reporting in one UK accident and emergency department
Tighe, C.M., Woloshynowych, M., Brown, R., Wears, B. and Vincent, C. 2006. Incident reporting in one UK accident and emergency department. Accident and Emergency Nursing. 14 (1), pp. 27-37. https://doi.org/10.1016/j.aaen.2005.10.001

PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.
Wilson, N.D., Ross, L.J., Crow, T.J. and Volpi, E.V. 2006. PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes. Cytogenetic and Genome Research. 114, pp. 137-139. https://doi.org/10.1159/000093329

The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci.
Laun, K., Coggill, P., Palmer, S., Sims, S., Ning, Z., Ragoussis, J., Volpi, E., Wilson, N., Beck, S., Ziegler, A. and Volz, A. 2006. The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci. PLoS Genetics. 2 (5) e73. https://doi.org/10.1371/journal.pgen.0020073

The effects of stress on surgical performance.
Wetzel, C. M., Kneebone, R., Woloshynowych, M., Nestel, D., Moorthy, K., Kidd, J. and Darzi, A. 2006. The effects of stress on surgical performance. The American Journal of Surgery. 191 (1), pp. 5-10. https://doi.org/10.1016/j.amjsurg.2005.08.034

Techniques used in the investigation and analysis of critical incidents in healthcare
Rogers, S, Taylor-Adams, S. and Woloshynowych, M. 2006. Techniques used in the investigation and analysis of critical incidents in healthcare. in: Walshe, K. and Boaden, R. (ed.) Patient Safety: Research into Practice Maidenhead, UK Open University Press. pp. 130-143

An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism.
Bowl, M.R., Nesbit, M.A., Harding, B., Levy, E., Jefferson, A., Volpi, E.V., Rizzoti, K., Lovell-Badge, R., Schlessinger, D., Whyte, M.P. and Thakker, R.V. 2005. An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism. Journal of Clinical Investigation. 115 (10), pp. 2822-2831. https://doi.org/10.1172/jci24156

The investigation and analysis of critical incidents and adverse events in healthcare
Woloshynowych, M., Rogers, S., Taylor-Adams, S. and Vincent, C. 2005. The investigation and analysis of critical incidents and adverse events in healthcare. Health Technology Assessment. 9 (19). https://doi.org/10.3310/hta9190

Double-skin facades: Improving performance and reducing costs
Ford, B. and Schiano-Phan, R. 2005. Double-skin facades: Improving performance and reducing costs. Plea 2005: The 22nd Conference on Passive & Low Energy Architecture. Beirut, Lebanon 13-16 November 2005

The development of passive downdraught evaporative cooling systems using porous ceramic evaporators and their application in residential buildings
Schiano-Phan, R. 2004. The development of passive downdraught evaporative cooling systems using porous ceramic evaporators and their application in residential buildings. PhD thesis Architectural Association School of Architecture, validated by the Open University

Error Reduction in Medicine: Final report to the Nuffield Trust
Lyons, M., Woloshynowych, M., Adams, S. and Vincent, C. 2004. Error Reduction in Medicine: Final report to the Nuffield Trust. Nuffield Trust.

Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice
Yalcin, B., Fullerton, J., Miller, S., Keays, D.A., Brady, S., Bhomra, A., Jefferson, A., Volpi, E., Copley, R.R., Flint, J. and Mott, R. 2004. Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.0401189101

Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region
Davies, S.J., Wise, C., Venkatesh, B., Mirza, G., Jefferson, A., Volpi, E.V. and Ragoussis, J. 2004. Mapping of three translocation breakpoints associated with orofacial clefting within 6p24 and identification of new transcripts within the region. Cytogenetic and Genome Research. 105, pp. 47-53. https://doi.org/10.1159/000078008

The application of downdraught evaporative cooling systems in non-domestic buildings. A case study: the Green Office, Tehran
Schiano-Phan, R. and Ford, B. 2004. The application of downdraught evaporative cooling systems in non-domestic buildings. A case study: the Green Office, Tehran. IFCO Conference. Tehran, Iran 15-18 February 2004

The development of passive downdraught evaporative cooling systems using porous ceramic evaporators and their application in residential buildings
Schiano-Phan, R. 2004. The development of passive downdraught evaporative cooling systems using porous ceramic evaporators and their application in residential buildings. in: Plea 2004: the 21st conference on passive & low energy architecture, Eindhoven, Netherlands, 19-22 September 2004 PLEA.

Cooling systems: principles and practice
Schiano-Phan, R. 2004. Cooling systems: principles and practice. 2nd Summer Academy of Mediterranean Solar Architecture (SAMSA). Rome, Italy 26 July – 6 August 2004

Retrospective case record review: a blunt instrument that needs sharpening
Neale, G. and Woloshynowych, M. 2003. Retrospective case record review: a blunt instrument that needs sharpening. BMJ Quality and Safety. 12 (1), pp. 2-3. https://doi.org/10.1136/qhc.12.1.2

Evaporative cooling using porous ceramic evaporators: product development and generic building integration
Schiano-Phan, R. and Ford, B. 2003. Evaporative cooling using porous ceramic evaporators: product development and generic building integration. The Plan: architecture & technologies in detail. 4, pp. 95-98.

Evaporative cooling using porous ceramic evaporators: product development and generic building integration
Schiano-Phan, R. and Ford, B. 2003. Evaporative cooling using porous ceramic evaporators: product development and generic building integration. in: PLEA 2003: the 20th conference on passive & low energy architecture, Santiago, Chile, 9 – 12 November 2003 PLEA.

Cohesion, but not too close
Volpi, E.V., Sheer, D. and Uhlmann, F. 2001. Cohesion, but not too close. Current Biology. 11 (10), p. R378. https://doi.org/10.1016/s0960-9822(01)00212-3

Exploring the causes of adverse events in British NHS hospital practice.
Neale, G., Woloshynowych, M. and Vincent, C. 2001. Exploring the causes of adverse events in British NHS hospital practice. Journal of the Royal Society of Medicine. 94, pp. 322-220. https://doi.org/10.1177/014107680109400702

Adverse events in British hospitals: preliminary retrospective record review
Vincent, C., Neale, G. and Woloshynowych, M. 2001. Adverse events in British hospitals: preliminary retrospective record review. BMJ. 322, pp. 517-519. https://doi.org/10.1136/bmj.322.7285.517

Passive evaporative cooling using porous ceramic evaporators
Schiano-Phan, R. 2001. Passive evaporative cooling using porous ceramic evaporators. Clima 2000. Naples, Italy 15-18 September 2001

Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei.
Volpi, E.V., Chevret, E., Jones, T., Vatcheva, R., Williamson, J., Beck, S., Campbell, R.D., Goldsworthy, M., Powis, S.H., Ragoussis, J., Trowsdale, J. and Sheer, D. 2000. Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei. Journal of Cell Science. 113 (Pt 9), pp. 1565-1576. https://doi.org/10.1242/jcs.113.9.1565

Mini review: form and function in the human interphase chromosome
Chevret, E., Volpi, E.V. and Sheer, D. 2000. Mini review: form and function in the human interphase chromosome. Cytogenetics and Cell Genetics. 90 (1-2), pp. 13-21. https://doi.org/10.1159/000015654

Thermal stability and energy efficiency in wine storage spaces: Ridge Winery, Lytton Springs, Healdsburg, California
Schiano-Phan, R. and Diaz, C. 2000. Thermal stability and energy efficiency in wine storage spaces: Ridge Winery, Lytton Springs, Healdsburg, California. in: World renewable energy congress VI, Brighton, 1-7 July 2000 Oxford Pergamon.

Specification of automatic vent opening devices for natural ventilation
Schiano-Phan, R., Bordass, W. and Ford, B. 2000. Specification of automatic vent opening devices for natural ventilation. Usable Buildings Trust.

Nucleotide sequence and chromosomal mapping of the 5S rDNA repeat of the crustacean Proasellus coxalis.
Pelliccia, F., Barzotti, R., Volpi, E.V., Bucciarelli, E. and Rocchi, A. 1998. Nucleotide sequence and chromosomal mapping of the 5S rDNA repeat of the crustacean Proasellus coxalis. Genome. 41 (1), pp. 129-123. https://doi.org/10.1139/g97-110

Numerical abnormalities of chromosomes 1 and 10 in endometrial adenocarcinoma: fluorescence in situ hybridization analysis of 23 archival paraffin-embedded samples.
Muresu, R., Cossu, A., Scarpa, A.M., Volpi, E.V., Rocca, P.C., Pintus, A., Tibiletti, M.G., Tanda, F., Pirastu, M. and Massarelli, G. 1998. Numerical abnormalities of chromosomes 1 and 10 in endometrial adenocarcinoma: fluorescence in situ hybridization analysis of 23 archival paraffin-embedded samples. Cancer Genetics and Cytogenetics. 107 (1), pp. 37-42. https://doi.org/10.1016/s0165-4608(98)00059-4

The eco-oriented project for the wine industry
Schiano-Phan, R. 1998. The eco-oriented project for the wine industry. WREN Congress V. Florence, Italy September 1998

Immediate Recovery of Psychomotor Function After Patient-Administered Nitrous Oxide/Oxygen Inhalation for Colonoscopy
Trojan, J., Saunders, B.P., Woloshynowych, M., Debinsky, H.S. and Williams, C.B. 1997. Immediate Recovery of Psychomotor Function After Patient-Administered Nitrous Oxide/Oxygen Inhalation for Colonoscopy. Endoscopy. 29 (1), pp. 17-22. https://doi.org/10.1055/s-2007-1004055

An integrated physical and genetic map spanning chromosome band 10q24.
Gray, I.C., Fallowfield, J., Ford, S., Nobile, C., Volpi, E.V. and Spurr, N.K. 1997. An integrated physical and genetic map spanning chromosome band 10q24. Genomics. 43 (1), pp. 85-88. https://doi.org/10.1006/geno.1997.4809

Detailed physical analysis of a 1.5-megabase YAC contig containing the MXI1 and ADRA2A genes.
Manca, A., Volpi, E.V., Laficara, F., Muresu, R., Gray, I.C., Spurr, N.K. and Nobile, C. 1997. Detailed physical analysis of a 1.5-megabase YAC contig containing the MXI1 and ADRA2A genes. Genomics. 45 (2), pp. 407-411. https://doi.org/10.1006/geno.1997.4924

The Patient Requests Form: a way of measuring what patients want from their general practitioner.
Valori, R., Woloshynowych, M., Bellenger, N., Aluvihare, V. and Salmon, P. 1996. The Patient Requests Form: a way of measuring what patients want from their general practitioner. Journal of Psychosomatic Research. 40 (1), pp. 87-94. https://doi.org/10.1016/0022-3999(95)00548-X

The measurement of beliefs about physical symptoms in English general practice patients
Salmon, P., Woloshynowych, M. and Valori, R. 1996. The measurement of beliefs about physical symptoms in English general practice patients. Social Science & Medicine. 42 (11), pp. 1561-1567. https://doi.org/10.1016/0277-9536(95)00263-4

Psychological aspects of gastrointestinal endoscopy: a review
Woloshynowych, M., Oakley, D.A., Saunders, B.P. and Williams, C.B. 1996. Psychological aspects of gastrointestinal endoscopy: a review. Endoscopy. 28 (9), pp. 763-767. https://doi.org/10.1055/s-2007-1005602

Taxonomic and biogeographic analysis of the Proasellus coxalis-group (Crustacea, Isopoda, Asellidae) in Sicily, with description of Proasellus montalentii n.sp.
Stoch, F., Valentino, F. and Volpi, E. 1996. Taxonomic and biogeographic analysis of the Proasellus coxalis-group (Crustacea, Isopoda, Asellidae) in Sicily, with description of Proasellus montalentii n.sp. Hydrobiologia. 317, pp. 247-258. https://doi.org/10.1007/bf00036474

More detailed characterization of some of the HL60 karyotypic features by fluorescence in situ hybridization.
Volpi, E.V., Vatcheva, R., Labella, T. and Gan, S.U. 1996. More detailed characterization of some of the HL60 karyotypic features by fluorescence in situ hybridization. Cancer Genetics and Cytogenetics. 87 (2), pp. 103-106. https://doi.org/10.1016/0165-4608(95)00214-6

Molecular and genetic studies on the region of translocation and duplication in the neuroblastoma cell line NGP at the 1p36.13-p36.32 chromosomal site
Casciano, I., Marchi, J.V.M., Muresu, R., Volpi, E.V., Rozzo, C., Opdenakker, G. and Romani, M. 1996. Molecular and genetic studies on the region of translocation and duplication in the neuroblastoma cell line NGP at the 1p36.13-p36.32 chromosomal site. Oncogene. 12 (10), pp. 2101-2108.

Simple DNA repeats and sex chromosome differentiation in asellus aquaticus (Crustacea, isopoda)
Volpi, E.V., Pelliccia, F., Lanza, V., Barzotti, R. and Rocchi, A. 1995. Simple DNA repeats and sex chromosome differentiation in asellus aquaticus (Crustacea, isopoda). Heredity. 75, p. 267–272. https://doi.org/10.1038/hdy.1995.134

Cytogenetic and molecular studies on the neuroblastoma cell line NGP: identification of a reciprocal t(1;15) involving the "consensus region" 1p36.1.
Muresu, R., Casciano I., Volpi, E.V., Siniscalco, M. and Romani, M. 1995. Cytogenetic and molecular studies on the neuroblastoma cell line NGP: identification of a reciprocal t(1;15) involving the "consensus region" 1p36.1. Genes, Chromosomes & Cancer. 13 (1), pp. 66-71. https://doi.org/10.1002/gcc.2870130111

Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57.
Volpi, E.V., Romani, M. and Siniscalco, M. 1994. Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57. Cytogenetics and Cell Genetics. 67, pp. 187-189. https://doi.org/10.1159/000133819

Telomeric sequences of ase/lus aquaticus (Crust. isop.)
Pelliccia, F., Volpi, E.V., Lanza, V., Gaddini, L., Balding, A. and Rocchi, A. 1994. Telomeric sequences of ase/lus aquaticus (Crust. isop.). Heredity. 72, pp. 78-80. https://doi.org/10.1038/hdy.1994.9

Concurrent mapping of an adenovirus 5/SV40 integration site and the U1 snRNA cluster (RNU1) within 400 kb of the chromosome region 1p36.1.
Romani, M., Baldini, A., Volpi, E., Casciano, I., Nobile, C., Muresu, R. and Siniscalco, M. 1994. Concurrent mapping of an adenovirus 5/SV40 integration site and the U1 snRNA cluster (RNU1) within 400 kb of the chromosome region 1p36.1. Cytogenetics and Cell Genetics. 67, pp. 37-40. https://doi.org/10.1159/000133793

MULTIPRINS: a method for multicolour primed in situ labelling
Volpi, E. and Baldini, A. 1993. MULTIPRINS: a method for multicolour primed in situ labelling. Chromosome Research. 1, pp. 257-260. https://doi.org/10.1007/bf00710131

Morphological differentiation of a sex chromosome and ribosomal genes in asellus aquaticus (Crust. Isop.)
Volpi, E.V., Pelliccia, F., Lanza, V., Di Castro, M. and Rocchi, A. 1992. Morphological differentiation of a sex chromosome and ribosomal genes in asellus aquaticus (Crust. Isop.). Heredity. https://doi.org/10.1038/hdy.1992.153

GATA repeats in the genome of Asellus aquaticus (Crustacea, Isopoda).
Pelliccia, F., Di Castro, M., Lanza, V., Volpi, E.V. and Rocchi, A. 1991. GATA repeats in the genome of Asellus aquaticus (Crustacea, Isopoda). Chromosoma. 100, pp. 152-155. https://doi.org/10.1007/bf00337243

Light-dark cycle and mitotic index in Asellus aquaticus (L.) (Crustacea, Isopoda)
Valentino, F., Volpi, E.V., Antolini, R. and Migliore, L. 1990. Light-dark cycle and mitotic index in Asellus aquaticus (L.) (Crustacea, Isopoda). Genetica. 82, pp. 147-150. https://doi.org/10.1007/bf00124645

The genetic isolation between some populations of Proasellus coxalis
Volpi, E.V., Antolini, R. and Valentino, F. 1989. The genetic isolation between some populations of Proasellus coxalis. Journal of Zoological Systematics and Evolutionary Research. 27 (3), pp. 246-251. https://doi.org/10.1111/j.1439-0469.1989.tb00346.x

Characterization of the karyotype of proasellus meridianusby differential staining techniques
Di Castro, M., Lanza, V., Volpi, E.V. and Rocchi, A. 1989. Characterization of the karyotype of proasellus meridianusby differential staining techniques. Caryologia. 42 (3-4), pp. 235-242. https://doi.org/10.1080/00087114.1989.10796970

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