Life Sciences

CollegeLiberal Arts and Sciences
HeadProf Alistair Mathie
DeputyDr Ian Locke
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The challenge of biocompatibility evaluation of biocomposites

Book chapter

Iqbal, H.M.N. and Keshavarz, T. 2017. The challenge of biocompatibility evaluation of biocomposites. in: Ambrosio, L. (ed.) Biomedical Composites. 2nd ed. Woodhead Publishing. pp. 303-334

Evaluating Inflammatory and Genotoxic Consequences of Adiposity in Adolescents: a Non-Invasive Approach

Conference paper

Usman, M. and Volpi, E. 2017. Evaluating Inflammatory and Genotoxic Consequences of Adiposity in Adolescents: a Non-Invasive Approach. The 12th International Conference and 5th Asian Congress on Environmental Mutagens. Korea 12 - 16 Nov 2017 Korean Environmental Mutagen Society.

Why should Britain Care about Salmonella Dublin?

Other

Mohammed, M. 2017. Why should Britain Care about Salmonella Dublin?

Whole genome sequencing reveals the secrets of Salmonella Dublin invasome

Conference poster

Mohammed, M., Le Hello, S., Leekitcharoenphon, P. and Hendriksen, R. 2017. Whole genome sequencing reveals the secrets of Salmonella Dublin invasome. European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Vienna, Austria 25 Apr - 21 Jul 2017

Genome Instability in Childhood Obesity – a potential role for bariatric surgery in cancer prevention?

Conference poster

Usman, M. and Volpi, E. 2017. Genome Instability in Childhood Obesity – a potential role for bariatric surgery in cancer prevention? Severe Paediatric Obesity: Current Medical and Surgical Management Paradigms - A Global Perspective. London 18 Jul 2017 International Consortium of Adolescent Bariatric Surgeons (ICABS).

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1

Journal article

Lawrence, K.M., Jones, R.C., Jackson, T.R., Baylie, R.L., Abbott, B., Bruhn-Olszewska, B., Board, T.N., Locke, I.C., Richardson, S.M. and Townsend, P.A. 2017. Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1. Scientific Reports. 7 (1), p. 5147 5147. https://doi.org/10.1038/s41598-017-04367-4

The invasome of Salmonella Dublin as revealed by whole genome sequencing

Journal article

Mohammed, M., Le Hello, S., Leekitcharoenphon, P. and Hendriksen, R. 2017. The invasome of Salmonella Dublin as revealed by whole genome sequencing . BMC Infectious Diseases. 17, p. 544 544. https://doi.org/10.1186/s12879-017-2628-x

Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold

Article

Basnett, P., Lukasiewicz, B., Marcello, E., Kaur, H., Knowles, J.C. and Roy, I. 2017. Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold. Microbial Biotechnology. 10 (6), pp. 1384-1399. https://doi.org/10.1111/1751-7915.12782

Alcohol metabolism: implications for nutrution and health

Book chapter

Patel, V.B. and Preedy, V.R. 2017. Alcohol metabolism: implications for nutrution and health. in: Geissler, C. and Powers, H. (ed.) Human Nutrition, 13th Edition Oxford Oxford University Press. pp. 216-235

Ethnic differences in the +405 and −460 vascular endothelial growth factor polymorphisms and peripheral neuropathy in patients with diabetes residing in a North London, community in the United Kingdom

Journal article

Zitouni, K., Tinworth, L. and Earle, K.A. 2017. Ethnic differences in the +405 and −460 vascular endothelial growth factor polymorphisms and peripheral neuropathy in patients with diabetes residing in a North London, community in the United Kingdom. BMC Neurology. 17, p. 125 125. https://doi.org/10.1186/s12883-017-0905-3

Activation of the pro-resolving receptor Fpr2 attenuates inflammatory microglial activation

Conference poster

Wickstead, E., Getting, S.J., Biggs, C.S. and McArthur, S. 2017. Activation of the pro-resolving receptor Fpr2 attenuates inflammatory microglial activation. BNA Festival of Neuroscience. Birmingham 10 - 13 Apr 2017 Sage. https://doi.org/10.1177/2398212817705279

The effect of the selective MC3 agonist PG990 on high density human chondrocytes micromass cultures activated by TNF-alpha

Conference poster

Getting, S.J., Can, V.C., Locke, I.C. and Grieco, P 2017. The effect of the selective MC3 agonist PG990 on high density human chondrocytes micromass cultures activated by TNF-alpha. World Congress on Inflammation. London 08 - 12 Jul 2017

Fpr2 and neuroinflammation: selective agonists with synergistic anti-oxidative and pro-resolving effects

Conference poster

Wickstead, E., Getting, S.J., Biggs, C.S. and McArthur, S. 2017. Fpr2 and neuroinflammation: selective agonists with synergistic anti-oxidative and pro-resolving effects. World Congress on Inflammation. London 08 - 12 Jul 2017

PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers

Article

Coffey, G., Rani, A., Betz, A., Pak, Y., Haberstock-Debic, H., Pandey, A., Hollenbach, S., Gretler, D.D., Mant, T., Jurcevic, S. and Simha, U. 2017. PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers. Journal of Clinical Pharmacology. 57 (2), pp. 194-210. https://doi.org/10.1002/jcph.794

Lifelong exercise, but not short-term high-intensity interval training, increases GDF11, a marker of successful aging: a preliminary investigation

Article

Elliott, B., Herbert, P., Sculthorpe, N., Grace, F., Stratton, D. and Hayes, L. 2017. Lifelong exercise, but not short-term high-intensity interval training, increases GDF11, a marker of successful aging: a preliminary investigation. Physiological Report. 5 (13), p. e13343 e13343. https://doi.org/10.14814/phy2.13343

Gamification in Higher Education: Students and Academics Interest in Gaming

Conference paper

Kimmitt, P.T. 2017. Gamification in Higher Education: Students and Academics Interest in Gaming. 9th Annual International Conference on Education and New Learning Technologies. Barcelona, Spain 03 - 05 Jul 2017 IATED Academy. https://doi.org/10.21125/edulearn.2017.2258

Using virtual reality to prepare Bioscience students for practical classes

Conference paper

Coleman, S.K., Volpi, E. and Smith, C.L. 2017. Using virtual reality to prepare Bioscience students for practical classes. 16th Westminster Symposium Innovate!. University of Westminster, London 22 - 22 Jun 2017

The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective?

Article

Nunn, A.V.W., Guy, G.W. and Bell, J.D. 2017. The Hormesis of Thinking: A Deeper Quantum Thermodynamic Perspective? International Journal of Neurorehabilitation. 4 (3), p. 272 272. https://doi.org/10.4172/2376-0281.1000272

A review of the evidence assessing impact of social prescribing on healthcare demand and cost implications

Technical report

Polley, M.J. and Pilkington, K. 2017. A review of the evidence assessing impact of social prescribing on healthcare demand and cost implications. University of Westminster.

Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas

Journal article

Presneau, Nadège, Duhamel, L.A., Ye, H., Tirabosco, R., Flanagan, A.M. and Eskandarpour, M. 2017. Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas. British Journal of Cancer. 117, pp. 398-408. https://doi.org/10.1038/bjc.2017.174

Increasing accessibility of students to laboratory classes through the use of Virtual laboratory simulations

Conference keynote

Smith, C.L. and Coleman, S.K. 2017. Increasing accessibility of students to laboratory classes through the use of Virtual laboratory simulations . UALL Work and Learning Network Annual Conference 2017 - Leading the Way: Shaping Practice in the Workplace and the Academy.. Middlesex University 23 - 23 Jun 2017

Investigation of the diversity and safety of the predominant Bacillus pumilus sensu lato and other Bacillus species involved in the alkaline fermentation of cassava leaves for the production of Ntoba Mbodi

Article

Mbozoa, A.B.V., Kobawilaa, S.C., Anyogu, A., Awamariab, B., Louembea, D., Sutherland, J.P. and Ouoba, L.I.I. 2017. Investigation of the diversity and safety of the predominant Bacillus pumilus sensu lato and other Bacillus species involved in the alkaline fermentation of cassava leaves for the production of Ntoba Mbodi. Food Control. 82, pp. 154-162. https://doi.org/10.1016/j.foodcont.2017.06.018

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

Article

Hameed, S., Patterson, M., Dhillo, W.S., Rahman, S.A., Ma, Y., Holton, C., Gogakos, A., Yeo, G.S.H., Lam, B.Y.H., Polex-Wolf, J., Fenske, W., Bell, J.D., Anastasovska, J., Samarut, J., Bloom, S.R., Bassett, J.H.D., Williams, G.R. and Gardiner, J.V. 2017. Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight. Cell Reports. 19 (11), pp. 2202-2219. https://doi.org/10.1016/j.celrep.2017.05.066

A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities

Conference paper

Villarini, B., Asaturyan, H., Thomas, E.L., Mould, R. and Bell, J.D. 2017. A Framework for Morphological Feature Extraction of Organs from MR Images for Detection and Classification of Abnormalities. Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (CBMS’17). Thessaloniki, Greece 22 - 24 Jun 2017 IEEE . https://doi.org/10.1109/CBMS.2017.49

Repeated batch for dye degradation in an airlift bioreactor by laccase entrapped in copper alginate

Article

Teerapatsakul, C., Parra, R., Keshavarz, T. and Chitradon, L. 2017. Repeated batch for dye degradation in an airlift bioreactor by laccase entrapped in copper alginate. International Biodeterioration & Biodegradation. 120, pp. 52-57. https://doi.org/10.1016/j.ibiod.2017.02.001

Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology

Book chapter

Lange, S., Kholia, S., Kosgodage, U. and Inal, J.M. 2017. Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology. in: Nicholas, A.P., Bhattacharya, S. and Thompson, P.R. (ed.) Protein Deimination in Human Health and Disease Cham, Switzerland Springer. pp. 413-425

Protein Deimination in Protein Misfolding Disorders - Modelled in Human induced Pluripotent Stem Cells (iPSCs)

Book chapter

Lange, S., Wray, S., Devine, M., Matarin, M. and Hardy, J. 2017. Protein Deimination in Protein Misfolding Disorders - Modelled in Human induced Pluripotent Stem Cells (iPSCs). in: Nicholas, A.P., Battacharya, S.K. and Thompson, P.R. (ed.) Protein Deimination in Human Health and Disease Cham, Switzerland Springer. pp. 227-239

Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?

Journal article

Lange, S., Gallagher, M, Kholia, S., Kosgodage, U., Hristova, M., Hardy, J. and Inal, J.M. 2017. Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release? International Journal of Molecular Sciences. 18 (6) 1196. https://doi.org/10.3390/ijms18061196

Fluorescence in situ Hybridization (FISH): challenges and opportunities in the post-genomic era

Conference paper

Volpi, E. 2017. Fluorescence in situ Hybridization (FISH): challenges and opportunities in the post-genomic era. Applications of in situ hybridisation in research and disease. Cancer Research UK Cambridge Institute, Cambridge 17 - 18 May 2017

Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Article

Adema, C.M., Hillier, L.W., Jones, C.S., Loker, E.S., Knight, M., Minx, P., Oliveira, G., Raghavan, N., Shedlock, A., Rodrigues do Amaral, L., Arican-Goktas, H.D., Assis, A.G., Baba, E.H., Baron, O.L., Bayne, C.J., Bickham-Wright, U., Biggar, K.K., Blouin, M., Bonning, B.C., Botka, C., Bridger, J.M., Buckley, K.M., Buddenborg, S.K., Caldeira, R.L., Carleton, J., Carvalho, O.S., Castillo, M.G., Chalmers, I.W., Christensens, M., Clifton, S., Cosseau, C., Coustau, C., Cripps, R.M., Cuesta-Astroz, Y., Cummins, S.F., di Stephano, L., Dinguirard, N., Duval, D., Emrich, S., Feschotte, C., Feyereisen, R., FitzGerald, P., Fronick, C., Fulton, L., Galinier, R., Gave, S.G., Geusz, M., Geyer, K.K., Giraldo-Calderón, G.I., Gomes, M.D.S., Gordy, M.A., Gourbal, B., Grunau, C., Hanington, P.C., Hoffmann, K.F., Hughes, D., Humphries, J., Jackson, D.J., Jannotti-Passos, L.K., Jeremias, W.D.J., Jobling, S., Kamel, B., Kapusta, A., Kaur, S., Koene, J.M., Kohn, A.B., Lawson, D., Lawton, S.P., Liang, D., Limpanont, Y., Liu, S., Lockyer, A.E., Lovato, T.L., Ludolf, F., Magrini, V., McManus, D.P., Medina, M., Misra, M., Mitta, G., Mkoji, G.M., Montague, M.J., Montelongo, C., Moroz, L.L., Munoz-Torres, M.C., Niazi, U., Noble, L.R., Oliveira,, F.S., Pais, F.B., Papenfuss, A.T., Peace, R., Pena, J.J., Pila, E.A., Quelais, T., Raney, B.J., Rast, J.P., Rollinson, D., Rosse, I.C., Rotgans, B., Routledge, E.J., Ryan, K.M., Scholte, L.L.S., Storey, K.B., Swain, M., Tennessen, J.A., Tomlinson, C., Trujillo, D.L., Volpi, E., Walker, A.J., Wang, T., Wannaporn, I., Warren, W.C., Wu, X.J., Yoshino, T.P., Yusuf, M., Zhang, S.M., Zhao, M. and Wilson, R.K. 2017. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications. 8, p. 15451 15451. https://doi.org/10.1038/ncomms15451

Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration

Journal article

Rai, R., Roether, J.A., Knowles, J.C., Mordan, N., Salih, V., Locke, I.C., Gordge, M.P., McCormick, A., Mohn, D., Stark, W.J., Keshavarz, T., Boccaccini, A.R. and Roy, I. 2017. Highly elastomeric poly(3-hydroxyoctanoate) based natural polymer composite for enhanced keratinocyte regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials . 66 (7), pp. 326-335. https://doi.org/10.1080/00914037.2016.1217530

Useful Plants - Medicines

Book chapter

Booker, A., Allkin, B., Patmore, K., Black, N., Canteiro, C., Dauncy, E., Edwards, S., Forest, F., Giovannini, P., Howes, M.J., Hudson, A., Irving, J., Leon, C., Milliken, W., Lughadha, E.N., Schippmann, U. and Simmonds, M.S.J. 2017. Useful Plants - Medicines. in: Willis, K.J. (ed.) The State of the World's Plants. Report London, UK The Board of Trustees of the Royal Botanic Gardens, Kew. pp. 22-29

Using Labster to improve Bioscience student learning and engagement in practical classes

Conference poster

Smith, C.L. and Coleman, S.K. 2017. Using Labster to improve Bioscience student learning and engagement in practical classes. Heads of Biological Sciences, Royal Society of Biology. Spring 2017 meeting.. University of Leicester 10 - 11 May 2017

Influence of soy fortification on microbial diversity during cassava fermentation and subsequent physicochemical characteristics of garri

Article

Ahaotu, N.N., Anyogu, A., Obioha, P., Aririatu, L., Ibekwe, V., Oranusi, S., Sutherland, P. and Ouoba, L. 2017. Influence of soy fortification on microbial diversity during cassava fermentation and subsequent physicochemical characteristics of garri. Food Microbiology. 66, pp. 165-172. https://doi.org/10.1016/j.fm.2017.04.019

Synthesis of graft copolymers based on hyaluronan and poly(3-hydroxyalkanoates)

Journal article

Huerta-Angeles, G., Brandejsová, M., Nigmatullin, R., Kopecká, K., Vágnerová, H., Šmejkalová, D., Roy, I. and Velebný, V. 2017. Synthesis of graft copolymers based on hyaluronan and poly(3-hydroxyalkanoates). Carbohydrate Polymers. 171, pp. 220-228. https://doi.org/10.1016/j.carbpol.2017.05.011

Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy

Journal article

Kosgodage, U., Trindade R.P., Thompson, P.R., Inal, J.M. and Lange, S. 2017. Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy. International Journal of Molecular Sciences. 18 (5) 1007. https://doi.org/10.3390/ijms18051007

Influences on GP coping and resilience: a qualitative study in primary care

Journal article

Cheshire, A., Ridge, Damien T., Hughes, J., Peters, D., Panagioti, M., Simon, C. and Lewith, G. 2017. Influences on GP coping and resilience: a qualitative study in primary care. British Journal of General Practice. 67 (659), pp. E428-E436. https://doi.org/10.3399/bjgp17X690893

Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Journal article

Warner, E.F., Smith, M.J., Zhang, Q., Raheem, S., O’Hagan, D., O'Connell, M.A. and Kay, C.D. 2017. Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells. Molecular Nutrition & Food Research. 61 (9) 1700053. https://doi.org/10.1002/mnfr.201700053

Genomic and molecular characterization of a novel quorum sensing molecule in Bacillus licheniformis

Article

Esmaeilishirazifard, E., De Vizio, D., Moschos, S. and Keshavarz, T. 2017. Genomic and molecular characterization of a novel quorum sensing molecule in Bacillus licheniformis. AMB Express. 7, p. 78 78. https://doi.org/10.1186/s13568-017-0381-6

Characterisation of tabanid flies (Diptera: Tabanidae) in South Africa and Zambia and detection of protozoan parasites they are harbouring

Article

Taioe, M.O., Motloang, M.Y., Namangala, B., Chota, A., Molefe, N.I., Musinguzi, S.P, Suganuma, K., Hayes, P.M., Tsilo, T.J., Chainey, J., Inoue, N. and Thekisoe, O.M.M. 2017. Characterisation of tabanid flies (Diptera: Tabanidae) in South Africa and Zambia and detection of protozoan parasites they are harbouring. Parasitology. 144 (9), pp. 1162-1178. https://doi.org/10.1017/S0031182017000440


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