Life Sciences

CollegeLiberal Arts and Sciences
HeadProf Alistair Mathie
DeputyDr Ian Locke
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The biology of osteocytes

Journal article

Kogianni, Giolanta and Noble, Brendon S. 2009. The biology of osteocytes. Current Osteoporosis Reports. 5, pp. 81-86. https://doi.org/10.1007/s11914-007-0007-z

Guide to Receptors and Channels (GRAC), 4th edition

Article

Alexander, S.P.H., Mathie, A. and Peters, J.A. 2009. Guide to Receptors and Channels (GRAC), 4th edition. British Journal of Pharmacology. 158 (S1). https://doi.org/10.1111/j.1476-5381.2009.00499.x

Neuronal Potassium Channels

Book chapter

Alistair Mathie and Emma L. Veale 2009. Neuronal Potassium Channels. in: Binder, M.D., Hirokawa, N. and Windhorst, U. (ed.) Encyclopedia of Neuroscience Springer Nature. pp. 2792–2797

Activated Adult Neural Stem Cells Generate Distinct Laminin/Integrin Interactions During Regeneration of the Subependymal Zone Neurogenic Niche

Article

Kazanis, I, Lathia, J.D., Vadakkan, T.J., Mattson, M.P., Dickinon, M.E. and Ffrench-Constant, C. 2009. Activated Adult Neural Stem Cells Generate Distinct Laminin/Integrin Interactions During Regeneration of the Subependymal Zone Neurogenic Niche. GLIA. 57 (S13), p. S76. https://doi.org/10.1002/glia.20915

The Extracellular Matrix Glycoprotein Tenascin-C Controls the Activity of Directly Neurogenic Progenitors in the Ventricular Zone of the Mouse Embryonic Forebrain

Article

Kazanis, I and Ffrench-Constant, C. 2009. The Extracellular Matrix Glycoprotein Tenascin-C Controls the Activity of Directly Neurogenic Progenitors in the Ventricular Zone of the Mouse Embryonic Forebrain. GLIA. 57 (S13), pp. S83-S84. https://doi.org/10.1002/glia.20915

The subependymal zone neurogenic niche: a beating heart in the centre of the brain: how plastic is adult neurogenesis? Opportunities for therapy and questions to be addressed

Journal article

Kazanis, I. 2009. The subependymal zone neurogenic niche: a beating heart in the centre of the brain: how plastic is adult neurogenesis? Opportunities for therapy and questions to be addressed. Brain. 132 (11), p. 2909–2921. https://doi.org/10.1093/brain/awp237

Effects of dynamic and static stretching on vertical jump performance and electromyographic activity.

Journal article

Hough, P., Ross, E. and Howatson, G. 2009. Effects of dynamic and static stretching on vertical jump performance and electromyographic activity. Journal of Strength and Conditioning Research. 23 (2), pp. 507-512. https://doi.org/10.1519/jsc.0b013e31818cc65d

Lean Body Mass is Reduced in Preterm Infants at Term Age

Article

Vasu, V., Thomas, E.L., Durighel, G., Uthaya, S., Bell, J.D. and Modi, N. 2009. Lean Body Mass is Reduced in Preterm Infants at Term Age. Acta Paediatrica. 98 (s460). https://doi.org/10.1111/j.1651-2227.2009.01482_1.x

Immune evasion during varicella zoster virus infection of keratinocytes

Journal article

Black, A.P., Jones, L., Malavige, G.N. and Ogg, G.S. 2009. Immune evasion during varicella zoster virus infection of keratinocytes. Clinical and Experimental Dermatology. 34 (8), pp. e941-e944. https://doi.org/10.1111/j.1365-2230.2009.03350.x

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target

Journal article

Nilu Wansadhipathi-Kannangara, John Mina, Ssu-Ying Pan, Nilu Wansadhipathi, Catherine Bruce, Hosam Shams-Eldin, Ralph Schwarz, P.G. Steel and Paul W. Denny 2009. The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target. Molecular and Biochemical Parasitology. 168 (2009), pp. 16-23. https://doi.org/10.1016/j.molbiopara.2009.06.002

Serum myeloperoxidase: a novel biomarker for evaluation of patients with acute coronary syndrome.

Journal article

Gururajan, P., Gurumurthy, P., Nayar, P., Babu, S., Sarasabharati, A., Victor, D. and Cherian, K.M. 2009. Serum myeloperoxidase: a novel biomarker for evaluation of patients with acute coronary syndrome. Heart Asia. 1 (1), pp. 41-46. https://doi.org/10.1136/ha.2009.000778

Increased serum concentrations of Soluble CD40 Ligand as a prognostic marker in patients with Acute Coronary Syndrome.

Journal article

Gururajan, P., Gurumurthy, P., Nayar, P., Babu, S., Sarasabharati, A., Victor, D. and Cherian, K.M. 2009. Increased serum concentrations of Soluble CD40 Ligand as a prognostic marker in patients with Acute Coronary Syndrome. Indian Journal of Clinical Biochemistry. 24, pp. 229-233. https://doi.org/10.1007/s12291-009-0043-9

The effect of age and the H1c MAPT haplotype on MAPT expression in human brain

Journal article

Hayesmoore, J.B.G., Bray, N.J., Cross, W., Owen, M.J., O’Donovan, M.C. and Morris, H.R. 2009. The effect of age and the H1c MAPT haplotype on MAPT expression in human brain. Neurobiology of Aging. 30 (10), pp. 1652-1656. https://doi.org/10.1016/j.neurobiolaging.2007.12.017

Trichinella and the Nurse Cell

Book chapter

Guiliano, D.B. and Oksov, Y. 2009. Trichinella and the Nurse Cell. in: Schaible, U.E. and Haas, A. (ed.) Intracellular Niches of Microbes: A Pathogens Guide Through the Host Cell Wiley. pp. 669-688

Stat3 Activity Is Required for Gap Junctional Permeability in Normal Rat Liver Epithelial Cells

Journal article

Mulu Geletu, Chrystele Chaize, Rozanne Arulanandam, Adina Vultur, Claudia Kowolik, Aikaterini Anagnostopoulou, Richard Jove and Leda Raptis 2009. Stat3 Activity Is Required for Gap Junctional Permeability in Normal Rat Liver Epithelial Cells. DNA and Cell Biology. 28 (7), pp. 319-327. https://doi.org/10.1089/dna.2008.0833

Quantitative analysis of dynamic contrast-enhanced MR images based on bayesian P-splines

Journal article

Schmid, V.J., Whitcher, B., Padhani, A.R. and Yang, G.-Z. 2009. Quantitative analysis of dynamic contrast-enhanced MR images based on bayesian P-splines. IEEE Transactions on Medical Imaging. 28 (6), pp. 789-798. https://doi.org/10.1109/tmi.2008.2007326

Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps

Journal article

Rose, C.J., Mills, S.J., O'Connor, J.P.B., Buonaccorsi, G.A., Roberts, C., Watson, Y., Cheung, S., Zhao, S., Whitcher, B., Jackson, A. and Parker, G.J.M. 2009. Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magnetic Resonance in Medicine. 62 (2), pp. 488-499. https://doi.org/10.1002/mrm.22003

A bayesian hierarchical model for the analysis of a longitudinal dynamic contrast-enhanced MRI oncology study

Journal article

Schmid, V.J., Whitcher, B., Padhani, A.R., Jane Taylor, N. and Yang, G.-Z. 2009. A bayesian hierarchical model for the analysis of a longitudinal dynamic contrast-enhanced MRI oncology study. Magnetic Resonance in Medicine. 61 (1), pp. 163-174. https://doi.org/10.1002/mrm.21807

Anatomically-distinct genetic associations of APOE e{open}4 allele load with regional cortical atrophy in Alzheimer's disease

Journal article

Filippini, N., Rao, A., Wetten, S., Gibson, R.A., Borrie, M., Guzman, D., Kertesz, A., Loy-English, I., Williams, J., Nichols, T., Whitcher, B. and Matthews, P.M. 2009. Anatomically-distinct genetic associations of APOE e{open}4 allele load with regional cortical atrophy in Alzheimer's disease. NeuroImage. 44 (3), pp. 724-728. https://doi.org/10.1016/j.neuroimage.2008.10.003

Variational Bayesian inference for a nonlinear forward model

Journal article

Chappell, M.A., Groves, A.R., Whitcher, B. and Woolrich, M.W. 2009. Variational Bayesian inference for a nonlinear forward model. IEEE Transactions on Signal Processing. 57 (1), pp. 223-236. https://doi.org/10.1109/tsp.2008.2005752

Agonist occupancy is essential for forward trafficking of AMPA receptors.

Journal article

Coleman, S.K., Möykkynen, T., Jouppila, A., Koskelainen, S., Rivera, C., Korpi, E.R. and Keinänen, K. 2009. Agonist occupancy is essential for forward trafficking of AMPA receptors. Journal of Neuroscience. 29 (2), pp. 303-312. https://doi.org/10.1523/jneurosci.3953-08.2009

Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique.

Journal article

Khiroug, S.S., Pryazhnikov, E., Coleman, S.K., Jeromin, A., Keinänen, K. and Khiroug, L. 2009. Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique. BMC Neuroscience. 10 141. https://doi.org/10.1186/1471-2202-10-141

Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations

Edited issue

Tommi P. Möykkynen, Coleman, S.K., Kari Keinänen, David M. Lovinger and Esa R. Korpi 2009. Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations. Alcohol. 43 (4), pp. 277-284. https://doi.org/10.1016/j.alcohol.2009.04.005

DECIPHER: Shedding Light on Chromosomal Imbalance and Phenotype Interpretation

Conference paper

Corpas, M., Richards, S., Bevan, P., van Vooren, S., Pettett, R., Firth, H. and Carter, N. 2009. DECIPHER: Shedding Light on Chromosomal Imbalance and Phenotype Interpretation. 7th European Cytogenetics Conference. Stockholm, Sweden 04 - 07 Jul 2009

DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources.

Journal article

Firth, H.V., Richards, S.M., Bevan, A.P., Clayton, S., Corpas, M., Rajan, D., Van Vooren, S., Moreau, Y., Pettett, R.M. and Carter, N.P. 2009. DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources. The American Journal of Human Genetics. 84 (4), pp. P524-533. https://doi.org/10.1016/j.ajhg.2009.03.010

Mapping of partially overlapping de novo deletions across an autism susceptibility region (AUTS5) in two unrelated individuals affected by developmental delays with communication impairment.

Journal article

Newbury, D.F., Warburton, P.C., Wilson, N., Bacchelli, E., Carone, S., International Molecular Genetic Study of Autism Consortium, Lamb, J.A., Maestrini, E., Monaco, A.P. and Volpi, E. 2009. Mapping of partially overlapping de novo deletions across an autism susceptibility region (AUTS5) in two unrelated individuals affected by developmental delays with communication impairment. American Journal of Medical Genetics Part A. 149A (4), pp. 588-597. https://doi.org/10.1002/ajmg.a.32704

HAC stability in murine cells is influenced by nuclear localization and chromatin organization.

Journal article

Moralli, D., Chan, D.Y., Jefferson, A., Volpi, E.V. and Monaco, Z.L. 2009. HAC stability in murine cells is influenced by nuclear localization and chromatin organization. BMC Cell Biology. 10 18. https://doi.org/10.1186/1471-2121-10-18

Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection.

Journal article

Sykes, N.H., Toma, C., Wilson, N., Volpi, E., Sousa, I., Pagnamenta, A.T., Tancredi, R., Battaglia, A., Maestrini, E., Bailey, A.J., Monaco, A.P. and International Molecular Genetic Study of Autism Consortium (IMGSAC) 2009. Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection. European Journal of Human Genetics. 17, pp. 1347-1353. https://doi.org/10.1038/ejhg.2009.47

Severe insulin resistance and intrauterine growth deficiency associated with haploin sufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism

Journal article

Suliman, S.G., Stanik, J., McCulloch, L.J., Wilson, N., Edghill, E.L., Misovicova, N., Gasperikova, D., Sandrikova, V., Elliott, K.S., Barak, L., Ellard, S., Volpi, E.V., Klimes, I. and Gloyn, A.L. 2009. Severe insulin resistance and intrauterine growth deficiency associated with haploin sufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. Diabetes. 58 (12), pp. 2954-2961. https://doi.org/10.2337/db09-0787

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer

Journal article

Kawano, Y., Diez, S., Uysal-Onganer, P., Darrington, R.S., Waxman, J. and Kypta, R.M. 2009. Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer. British Journal of Cancer. 100, pp. 1165-1174. https://doi.org/10.1038/sj.bjc.6604976

The use of cardiovascular biomarkers for the assessment of heart disease in men

Book chapter

Gaze, D.C. 2009. The use of cardiovascular biomarkers for the assessment of heart disease in men. in: Heart Disease in Men Nova Science Publishers. pp. 167-182

Alterations in left ventricular function and cardiac biomarkers as a consequence of repetitive endurance cycling

Journal article

Williams, K., Gregson, W., Robertson, C., Datson, N., Whyte, G., Murrell, C., Wilson, L., Ainslie, P., Ross, E., Shave, R., Gaze, D.C. and George, K. 2009. Alterations in left ventricular function and cardiac biomarkers as a consequence of repetitive endurance cycling. European Journal of Sport Science. 9 (2), pp. 97-105. https://doi.org/10.1080/17461390902763391

Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking

Journal article

George, K., Shave, R., Oxborough, D., Cable, T., Dawson, E., Artis, N., Gaze, D.C., Hew-Butler, T., Sharwood, K. and Noakes, T. 2009. Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking. European Journal of Echocardiography. 10 (2), p. 238–243. https://doi.org/10.1093/ejechocard/jen207

Cardiovascular Consequences of Completing a 160-km Ultramarathon

Journal article

Scott, J.M., Esch, B.T., Shave, R., Warburton, D.E., Gaze, D.C. and George, K. 2009. Cardiovascular Consequences of Completing a 160-km Ultramarathon. Medicine and Science in Sports and Exercise. 41 (1), pp. 26-34. https://doi.org/10.1249/mss.0b013e31818313ff

Cardiac troponin elevations in patients presenting with emergency orthopaedic trauma

Journal article

Gaze, D.C. 2009. Cardiac troponin elevations in patients presenting with emergency orthopaedic trauma. Injury. 40 (3), p. 338. https://doi.org/10.1016/j.injury.2008.10.031

The diagnostic and prognostic value of tissue Doppler imaging during dobutamine stress echocardiography in end-stage renal disease

Article

Sharma, R., Mehta, R.L., Brecker, S.J.D., Gaze, D.C., Gregson, H., Streather, C.P., Collinson, P.O. and Pellerin, D. 2009. The diagnostic and prognostic value of tissue Doppler imaging during dobutamine stress echocardiography in end-stage renal disease. Coronary Artery Disease. 20 (3), pp. 230-237. https://doi.org/10.1097/mca.0b013e32832ac5eb

Assay imprecision and 99th-percentile reference value of a high-sensitivity cardiac troponin I assay

Journal article

Collinson, P.O., Clifford-Mobley, O., Gaze, D.C., Boa, F. and Senior, R. 2009. Assay imprecision and 99th-percentile reference value of a high-sensitivity cardiac troponin I assay. Clinical Chemistry. 55 (7), p. 1433–1434. https://doi.org/10.1373/clinchem.2009.124925

Rosiglitazone reduces the development and rupture of experimental aortic aneurysms

Journal article

Jones, A., Deb, R., Torsney, E., Howe, F., Dunkley, M., Gnaneswaran, Y., Gaze, D.C., Nasr, H., Loftus, I.M., Thompson, M.M. and Cockerill, G.W. 2009. Rosiglitazone reduces the development and rupture of experimental aortic aneurysms. Circulation. 119, p. 3125–3132. https://doi.org/10.1161/circulationaha.109.852467

Cardiac troponins in patients with renal failure. What are we measuring and when should we measure it?

Journal article

Collinson, P.O. and Gaze, D.C. 2009. Cardiac troponins in patients with renal failure. What are we measuring and when should we measure it? Annals of Clinical Biochemistry. 46 (4), pp. 269-270. https://doi.org/10.1258/acb.2009.009058

Ischemia Modified Albumin: A Novel Biomarker for the Detection of Cardiac Ischemia

Journal article

Gaze, D.C. 2009. Ischemia Modified Albumin: A Novel Biomarker for the Detection of Cardiac Ischemia. European Journal of Drug Metabolism and Pharmacokinetics. 24 (4), pp. 333-341. https://doi.org/10.2133/dmpk.24.333


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