Life Sciences

Yasar, Z., Elliott, B., Kyriakidou, Y., Nwokoma, C., Postlethwaite, R., Gaffney, C., Dewhurst, S. and Hayes, L. 2021. Sprint interval training (SIT) reduces serum epidermal growth factor (EGF), but not other inflammatory cytokines in trained older men. European Journal of Applied Physiology. 121, pp. 1909-1919. https://doi.org/10.1007/s00421-021-04635-2

D'alessio, S., Thorgeirsdóttir, Stefanía, Kraev, Igor, Skírnisson, Karl and Lange, S. 2021. Post-Translational Protein Deimination Signatures in Plasma and Plasma EVs of Reindeer ( Rangifer tarandus ). Biology. 10 (3) e222. https://doi.org/10.3390/biology10030222

Obioha, P., Ouoba, L.I.I., Anyogu, A., Awamaria, B., Atchia, S, Ojimelukwe, P.C, Sutherland, J.P and Ghoddusi, H. 2021. Identification and characterisation of the lactic acid bacteria associated with the traditional fermentation of a dairy fermented product. Brazilian Journal of Microbiology. 52, p. 869–881. https://doi.org/10.1007/s42770-021-00461-y

Ichim, M.C. and Booker, A. 2021. Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products. Frontiers in Pharmacology. 12 666850. https://doi.org/10.3389/fphar.2021.666850

Mohammed, M. 2021. Stop Superbugs!

Mould, R., Botchway, S, Parkinson, J., Thomas, E.L., Guy, G., Bell, J.D. and Nunn, A. 2021. Cannabidiol modulates mitochondrial redox and dynamics in MCF7 cancer cells: a study using fluorescence lifetime imaging microscopy of NAD(P)H. Frontiers in Molecular Biosciences. 8 630107. https://doi.org/10.3389/fmolb.2021.630107

Kristmundsson, Árni, Erlingsdóttir, Ásthildur and Lange, S. 2021. Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions. Biology. 10 (3) e177. https://doi.org/10.3390/biology10030177

Arisan, E., Rencuzogullari, O., Clara Cieza-Borrella, Miralles Arenas, F., Miriam Dwek, Lange, S. and Uysal Onganer, P. 2021. MiR-21 Is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells. International Journal of Molecular Sciences. 22 (4), p. e1557 1557. https://doi.org/10.3390/ijms22041557

Lange, S. and Ramirez, M.I. 2021. Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses. Frontiers in Cellular and Infection Microbiology. 11 642311. https://doi.org/10.3389/fcimb.2021.642311

Uysal Onganer, P., D'alessio, S., Mortoglou, M., Kraev, I. and Lange, S. 2021. Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. International Journal of Molecular Sciences. 22 (3) 1396. https://doi.org/10.3390/ijms22031396

Shrestha, S., Ghebremeskel, K., White, K., Minelli, C., Tewfik, I., Thapa, Panna and Tewfik, S. 2021. Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study. International Journal of Nanomedicine. 16, pp. 1977-1992. https://doi.org/10.2147/IJN.S276301

Tothova, Z., Valton, A., Gorelov, R., Vallurupalli, M., Krill-Burger, J.M., Holmes, A., Landers, C.C., Haydu, J.E., Malolepsza, E., Hartigan, C.R., Donahue, M., Popova, K.D., Koochaki, S.H.J., Venev, S.V., Rivera, J.F., Chen, E., Lage, K., Schenone, M., D'Andrea, A.D., Carr, S.A., Morgan, E.A., Dekker, J. and Ebert, B.L. 2021. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight. 6 (3) e142149. https://doi.org/10.1172/jci.insight.142149

Kyriakidou, Y., Wood, C., Ferrier, C., Dolci, A. and Elliott, B. 2021. The effect of Omega-3 polyunsaturated fatty acid supplementation on exercise-induced muscle damage. Journal of the International Society of Sports Nutrition. 18 (1) 9. https://doi.org/10.1186/s12970-020-00405-1

Lange, S., Arisan, E.D., Grant, G.H. and Uysal Onganer, P. 2021. MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species. MDPI Viruses. 13 (1), p. 117 10.3390/v13010117 . https://doi.org/10.3390/v13010117

Magnadóttir, B., Kraev, I., Dodds, A.W. and Lange, S. 2021. The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles—Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways. International Journal of Molecular Sciences. 22 (2) 875. https://doi.org/10.3390/ijms22020875

Mani, Priyadharshini, Fidal, V. T., Keshavarz, Taj, Chandra, T. S. and Kyazze, G. 2021. Laccase Immobilization Strategies for Application as a Cathode Catalyst in Microbial Fuel Cells for Azo Dye Decolourization. Frontiers in Microbiology. 11 620075. https://doi.org/10.3389/fmicb.2020.620075

Liu, J., Reeves, C., van der Pijl, R. and Thom, M. 2021. Glial regenerative cell types in the superficial cortex in cortical dysplasia subtypes. Epilepsy Research. 169 106529. https://doi.org/10.1016/j.eplepsyres.2020.106529

Patel, H. and Kukol, A. 2021. Integrating molecular modelling methods to advance influenza A virus drug discovery. Drug Discovery Today. 26 (2), pp. 503-510. https://doi.org/10.1016/j.drudis.2020.11.014

Burges Watson, D.L., Draper, A. and Willis, W.J. 2021. The chimera of choice in UK food policy 1976-2018. British Food Journal. 123 (4), pp. 1596-1609. https://doi.org/10.1108/BFJ-10-2020-0982

Lange, Sigrun 2021. Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair. Neural Regeneration Research. 16 (5), pp. 934-938. https://doi.org/10.4103/1673-5374.297058

Bizzotto, R., Jennison, C., Jones, A., Kurbasic, A., Kennedy, G., Bell, J.D., Thomas, E.L., Frost, G., Eriksen, R., Koivula, R., Brage, S., Kaye, J., Hattersley, A., Heggie, A., McEvoy, D., Hart, L.M., Beulens, J.W., Elders, P., Musholt, P.B., Ridderstråle, M., Hansen, T., Allin, K., Hansen, T., Vestergaard, H., Lundgaard, A.T., Thomsen, H.S., Masi, F., Tsirigos, K.D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T.J., Kokkola, T., Forgie, I., Giordano, G.N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M., Pedersen, O., Schwenk, J., Adamski, J., Franks, P., Walker, M., Pearson, E. and Mari, A. 2021. Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study. Diabetes Care. 44 (2), pp. 511-518. https://doi.org/10.2337/dc20-1567

Brown, D.R., Warner, A.R., Deb, S., Gough, L.A., Sparks, S.A. and McNaughton, L.R. 2021. The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial. Journal of Science and Medicine in Sport. 24 (1), pp. 92-97. https://doi.org/10.1016/j.jsams.2020.06.017

Alić, I., Goh, P.A., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, K.Y., Koschut, D., Brunmeir, R., Yeap, Y.J., O'Brien, N.L., Groet, J., Shao, X,, Havlicek, S., Dunn, N.R., Kvartsberg, H., Brinkmalm, G., Hithersay, R,, Startin, C., Hamburg, S., Phillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, J.E., Foo, J.N., Becker, D.L., Rostagno, A., Ghiso, J., Krsnik, Ž., Šimić, G., Kostović, I., Mitrečić, D., LonDownS Consortium, Francis, P.T., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H. and Nižetić, D. 2021. Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain. Molecular Psychiatry. 26, p. 5766–5788. https://doi.org/10.1038/s41380-020-0806-5

Hmedeh, C., Ghazeeri, G. and Tewfik, I. 2021. Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities. International Journal of Food Safety, Nutrition and Public Health. 6 (2), pp. 120-130. https://doi.org/10.1504/IJFSNPH.2021.113389

Mohammed, M. Forthcoming. Dr Manal Mohammed for The Independent on handwashing and hand-sanitisers. The Conversation.

Lange, S. 2020. Patterns in nature - the true art of microscopy. University of Westminster

András Ecker, Armando Romani, Sára Sáray, Szabolcs Káli, Michele Migliore, Joanne Falck, Sigrun Lange, Audrey Mercer, Alex M. Thomson, Eilif Muller, Michael W. Reimann and Srikanth Ramaswamy 2020. Cover Image, Volume 30, Issue 11. Hippocampus. 30 (11), p. C1. https://doi.org/10.1002/hipo.23273

Maragkoudaki, X., Naylor, M., Papacleovoulou, G., Stolarczyk, E., Rees, D., Pombo, J.M., Abu-Hayyeh, S., Czajka, A., Howard, J.K., Malik, A.N., Williamson, C., Poston, L. and Taylor, P.D. 2020. Supplementation with a prebiotic (polydextrose) in obese mouse pregnancy improves maternal glucose homeostasis and protects against offspring obesity. International Journal of Obesity. 44, pp. 2382-2393. https://doi.org/10.1038/s41366-020-00682-5

Savickas, V., Veale, E.L., Bhamra, S.K., Stewart, A.J., Mathie, A. and Corlett, S. 2020. Pharmacists detecting atrial fibrillation in general practice: a qualitative focus group study. BJGP Open. 4 (3) bjgpopen20X101042. https://doi.org/10.3399/bjgpopen20x101042

Aiste Steponenaite, Tatjana Lalic, Lynsey Atkinson, Liting Wei, Alistair Mathie, M. Zameel Cader and Gurprit S. Lall 2020. TASK-3 Two-Pore Potassium Channels drive neuronal excitability of the circadian clock and entrainment to challenging light environments. biorxiv.org. https://doi.org/10.1101/2020.07.27.222885

Tatjana Lalic, Aiste Steponenaite, Liting Wei, Sridhar R. Vasudevan, Alistair Mathie, Stuart N. Peirson, Gurprit S. Lall and M. Zameel Cader 2020. TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses. Nature Communications . 11 4614. https://doi.org/10.1038/s41467-020-17978-9

Savickas, Vilius, Stewart, Adrian J., Rees-Roberts, Melanie, Short, Vanessa, Bhamra, Sukvinder K., Corlett, Sarah A., Mathie, A. and Veale, Emma L. 2020. Opportunistic screening for atrial fibrillation by clinical pharmacists in UK general practice during the influenza vaccination season: A cross-sectional feasibility study. PLoS Medicine. 17 (7) e1003197. https://doi.org/10.1371/journal.pmed.1003197

Chipperfield, A.J., Thanaj, M. and Clough, G.F. 2020. Multiscale, multidomain analysis of microvascular flow dynamics. Experimental Physiology. 105 (9), pp. 1452-1458. https://doi.org/10.1113/ep087874

Kitching, V. and Tewfik, I. 2020. Natto and Vitamin K2: a promising nutraceutical aid for bone maintenance. International Journal of Food, Nutrition and Public Health.

Mbiatem, M. E. and Tewfik, I. 2020. Evaluating the effectiveness of a tailored health educational health toolkit to modulate Type 2 Diabetes Mellitus and restrain its complications. International Journal of Food, Nutrition and Public Health. 12 (1/2), pp. 41- 62.

Zubaidah, E., Valencia, V., Rifa'i, M., Srianta, I. and Tewfik, I. 2020. Investigating chemical changes during Snake fruit and Black tea Kombucha fermentation and the associated immunomodulatory activity in Salmonella typhi-infected mice. Potravinarstvo Slovak Journal of Food Sciences. 14, pp. 995-1000. https://doi.org/10.5219/1416

Wai K. Lau, Dhanuson Dharmasena, Harry Horsley, Nazila Jafari, James Malone-Lee, Eleanor Stride, Mohan Edirisinghe and Jennifer L. Rohn 2020. Novel antibiotic-loaded particles conferring eradication of deep tissue bacterial reservoirs for the treatment of chronic urinary tract infection. Journal of Controlled Release. 328, pp. 490-502. https://doi.org/10.1016/j.jconrel.2020.08.048

Basty, N., Liu, Yi, Cule, M., Thomas, E. Louise, Bell, J.D. and Whitcher, B. 2020. Preprint: Image Processing and Quality Control for Abdominal Magnetic Resonance Imaging in the UK Biobank. arXiv.

Atabaki-Pasdar, N., Ohlsson, M., Vinuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., Mutie, P. M., Fitipaldi, H., Fernandez, J., Dawed, A. Y., Giordano, G. N., Forgie, I. M., McDonald, T. J., Rutters, F., Cederberg, H., Chabanova, E., Dale, M., Masi, F. D., Thomas, C. E., Allin, K. H., Hansen, T. H., Heggie, A., Hong, M.-G., Elders, P. J., Kennedy, G., Kokkola, T., Pedersen, H. K., Mahajan, A., McEvoy, D., Pattou, F., Raverdy, V., Haussler, R. S., Sharma, S., Thomsen, H. S., Vangipurapu, J., Vestergaard, H., 't Hart, L. M. and Adamski, J. 2020. Preprint: Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study. medRxiv. https://doi.org/10.1101/2020.02.10.20021147

Kleine, Daria, Billamay, Somxay, Chanthavilay, Phetsavanh, Mongkhoune, Sodaly, Keokhamphoui, Chirapha, Souksakhone, Chanthala, Nouanthong, Phonethipsavanh, Khamphaphongphane, Bouaphan, Muller, Claude P. and Black, Antony P. 2020. Pertussis in Lao PDR: Seroprevalence and disease. International Journal of Infectious Diseases. 95, pp. p282-287. https://doi.org/10.1016/j.ijid.2020.03.074