Life Sciences

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HeadProf Alistair Mathie
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Cellular senescence in populations of postnatal brain Neural Stem Cells

Article

Anesti, M., Dimitriou, C., Gorgoulis, V. and Kazanis, I. 2019. Cellular senescence in populations of postnatal brain Neural Stem Cells. GLIA. 67 (S1), pp. E503-E504. https://doi.org/10.1002/glia.23675

Genetic studies of MRI liver fat content identify susceptibility variants with variable metabolic effects

Article

Parisinos, Constantinos, Wilman, Henry, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Hingorani, Aroon, Patel, Riyaz, Hemingway, Harry, Banerjee, Rajarshi and Yaghootkar, Hanieh 2019. Genetic studies of MRI liver fat content identify susceptibility variants with variable metabolic effects. Gut. 68 (Supplement 2), p. A110. https://doi.org/10.1136/gutjnl-2019-bsgabstracts.208

PTU-028 Genome-wide association study of MRI liver iron content in UK biobank identifies 3 susceptibility variants

Article

Parisinos, Constantinos, Wilman, Henry, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Hingorani, Aroon, Patel, Riyaz, Hemingway, Harry, Banerjee, Rajarshi and Yaghootkar, Hanieh 2019. PTU-028 Genome-wide association study of MRI liver iron content in UK biobank identifies 3 susceptibility variants. Gut. 68, pp. A125-A126. https://doi.org/10.1136/gutjnl-2019-bsgabstracts.237

Genome-wide association study of MRI liver iron content in 9,800 individuals yields new insights into its link with hepatic and extrahepatic diseases

Article

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Hingorani, A., Mahajan, A., Patel, R., Hemingway, H., Franks, P. W., Bell, J., Banerjee, R. and Yaghootkar, H. 2019. Genome-wide association study of MRI liver iron content in 9,800 individuals yields new insights into its link with hepatic and extrahepatic diseases. European Journal of Human Genetics. 27 (Supplment 2), p. 1148 Meeting Abstract C21.5.

Subcutaneous Abdominal Fat Has a Stronger Association with Prediabetes than Visceral Fat in Young Indians

Article

Wagh, Rucha H., Bawdekar, Rupali U., Alenaini, Wareed, Thomas, Elizabeth L., Bell, Jimmy David and Yajnik, Chittaranjan S. 2019. Subcutaneous Abdominal Fat Has a Stronger Association with Prediabetes than Visceral Fat in Young Indians. Diabetes. 68 (Supplement 1), pp. 2106-P. https://doi.org/10.2337/db19-2106-p

Genome-wide association studies of abdominal MRI scans identifies loci associated with liver fat and liver iron in the UK Biobank

Article

Wilman, Henry, Parisinos, Constantinos, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Banerjee, Rajarshi, Yaghootkar, Hanieh and Thomas, E. Louise 2019. Genome-wide association studies of abdominal MRI scans identifies loci associated with liver fat and liver iron in the UK Biobank. Journal of Hepatology. 70 (1, Supplement) E315. https://doi.org/10.1016/s0618-8278(19)30236-1

Knowledge and Attitude Towards Liver Cancer and Liver Cancer Screening Among HBV and HCV Patients in Vientiane, Lao PDR: a cross Sectional Study

Journal article

Cheung, Diana, Khounvisith, Vilaysone, Sitbounlang, Philavanh, Sathathone, Douangprachanh, Virachith, Siriphone, Phetsamone, Arounlangsy, Paboriboune, Phimpha and Black, Antony P. 2019. Knowledge and Attitude Towards Liver Cancer and Liver Cancer Screening Among HBV and HCV Patients in Vientiane, Lao PDR: a cross Sectional Study. Hepatology. 70 (S1), p. 627. https://doi.org/10.1002/hep.30941

Seroprotection at different levels of the healthcare system after routine vaccination with diphtheria-tetanus-pertussis whole cell--hepatitis B--haemophilus influenzae type B in Lao People’s Democratic Republic

Journal article

Hefele, Lisa, Syphan, Sengdavanh, Xayavong, Dalouny, Homsana, Anousin, Kleine, Daria, Chanthavilay, Phetsavanh, Nouanthong, Phonethipsavanh, Xaydalasouk, Kinnaly, Phathammavong, Outavong, Billamay, Somxay, Xeuatvongsa, Anonh, Reinharz, Daniel, Muller, Claude P. and Black, Anthony P. 2019. Seroprotection at different levels of the healthcare system after routine vaccination with diphtheria-tetanus-pertussis whole cell--hepatitis B--haemophilus influenzae type B in Lao People’s Democratic Republic. Clinical Infectious Diseases. 69 (12), pp. 2136-2144. https://doi.org/10.1093/cid/ciz143

Varicella zoster and fever rash surveillance in Lao People’s Democratic Republic

Journal article

Nouanthong, Phonethipsavanh, Hübschen, Judith M., Billamay, Somxay, Mongkhoune, Sodaly, Vilivong, Keooudomphone, Khounvisith, Vilaysone, Sinner, Regina, Grandadam, Marc, Phonekeo, Darouny, Black, Antony P. and Muller, Claude, P. 2019. Varicella zoster and fever rash surveillance in Lao People’s Democratic Republic. BMC Infectious Diseases. 19 392. https://doi.org/10.1186/s12879-019-3990-7

Livestock diseases threatening smallholder farmers in Lao people's Democratic Republic

Journal article

Pauly, M., Xaydalasouk, K., Innoula, N., Snoeck, C.J., Black, A.P., Pommasichan, S., Phoutana, V. and Muller, C.P. 2019. Livestock diseases threatening smallholder farmers in Lao people's Democratic Republic. International Journal of Infectious Diseases. 79 (Supplement 1) 71. https://doi.org/10.1016/j.ijid.2018.11.182

Effects of selenium supplementation on pregnancy outcome and disease progression in HIV-infected pregnant women in Lagos, Nigeria: Study protocol for a randomised, double-blind, placebo-controlled trial

Journal article

Okunade, K.S., John-Olabode, S., Akinsola, O.J., Akinajo, O., Akanmu, S.A. and Kanki, P.J. 2019. Effects of selenium supplementation on pregnancy outcome and disease progression in HIV-infected pregnant women in Lagos, Nigeria: Study protocol for a randomised, double-blind, placebo-controlled trial. Medicine. 98 (3) e12735. https://doi.org/10.1097/md.0000000000012735

Knowledge, attitudes and practices regarding vaccination among healthcare workers in Lao PDR

Journal article

Sengchaleun, V., Khampanisong, P., Aye-Soukhathammavong, P., Reinharz, D. and Black, A.P. 2019. Knowledge, attitudes and practices regarding vaccination among healthcare workers in Lao PDR. Southeast Asian Journal of Tropical Medicine and Public Health. 50 (2), pp. 383-391.

High prevalence of helminth infections in mother-child pairs from three central provinces of Lao People's Democratic Republic

Journal article

Pauly, Maude, Sayasinh, Kong, Muller, Claude P, Sayasone, Somphou and Black, A. 2019. High prevalence of helminth infections in mother-child pairs from three central provinces of Lao People's Democratic Republic. Parasite epidemiology and control. 7. https://doi.org/10.1016/j.parepi.2019.e00122

Cross-species transmission of poultry pathogens in backyard farms: ducks as carriers of chicken viruses

Journal article

Pauly, Maude, Snoeck, Chantal J, Phoutana, Vannaphone, Keosengthong, Amphone, Sausy, Aurélie, Khenkha, Latdavone, Nouanthong, Phonethipsavanh, Samountry, Bounthome, Jutavijittum, Prapan, Vilivong, Keooudomphone, Hübschen, Judith M., Black, A., Pommasichan, Sisavath and Muller, Claude P. 2019. Cross-species transmission of poultry pathogens in backyard farms: ducks as carriers of chicken viruses. Avian Pathology. 48 (6), pp. 503 - 511. https://doi.org/10.1080/03079457.2019.1628919

Response to the Letter from Garcia-Montojo and colleagues concerning our paper entitled, Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis.

Journal article

Garson, J.A., Usher, L., Al-Chalabi, A., Huggett, J., Day, E. and McCormick, A.L. 2019. Response to the Letter from Garcia-Montojo and colleagues concerning our paper entitled, Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 7 102. https://doi.org/10.1186/s40478-019-0756-9

Simplifying access to human genomic data: community platform Repositive.io

Article

Kovalevskaya, N. V., Whicher, C., Corpas, M., Shaw, R. and Nielsen, F. 2019. Simplifying access to human genomic data: community platform Repositive.io. European Journal of Human Genetics. 26 (S), p. 714. https://doi.org/10.1038/s41431-018-0247-7

Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration

Journal article

Jassem, W., Xystrakis, E., Ghnewa, Y.G., Yuksel, M., Pop, O., Martinez-Llordella, M., Jabri, Y., Huang, X., Lozano, J.J., Quaglia, A., Sanchez-Fueyo, A., Coussios, C.C., Rela, M., Friend, P., Heaton, N. and Ma, Y. 2019. Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration. Hepatology. 70 (2), pp. 682-695. https://doi.org/10.1002/hep.30475

Convergent Evolution of Copy Number Alterations in Multi-Centric Hepatocellular Carcinoma

Journal article

Carolin Lackner, Luca Quagliata, William Cross, Sebastian Ribi, Karl Heinimann, Viola Paradiso, Cristina Quintavalle, Monika Kovacova, Daniel Baumhoer, Salvatore Piscuoglio, Luigi Terracciano and Michal Kovac 2019. Convergent Evolution of Copy Number Alterations in Multi-Centric Hepatocellular Carcinoma. Scientific Reports. 9 4611. https://doi.org/10.1038/s41598-019-40843-9

Evolutionary history of human colitis-associated colorectal cancer

Journal article

Ann-Marie Baker, William Cross, Kit Curtius, Ibrahim Al Bakir, Chang-Ho Ryan Choi, Hayley Louise Davis, Daniel Temko, Sujata Biswas, Pierre Martinez, Marc J. Williams, James O. Lindsay, Roger Feakins, Roser Vega, Stephen J. Hayes, Tomlinson, I., Stuart A.C. McDonald, Morgan Moorghen, Andrew Silver, James E. East, Nicholas A. Wright, Lai Mun Wang, Manuel Rodriguez-Justo, Marnix Jansen, Ailsa L. Hart, Simon J. Leedham and Trevor Graham 2019. Evolutionary history of human colitis-associated colorectal cancer. Gut. 68, pp. 985-995. https://doi.org/10.1136/gutjnl-2018-316191

Preprint: Niche engineering drives early passage through an immune bottleneck in progression to colorectal cancer

Other

Chandler D. Gatenbee, Ann-Marie Baker, Ryan O. Schenck, Margarida Neves, Sara Yakub Hasan, Pierre Martinez, William C.H. Cross, Marnix Jansen, Manuel Rodriguez-Justo, Andrea Sottoriva, Simon Leedham, Mark Robertson-Tessi, Trevor A. Graham and Alexander Anderson 2019. Preprint: Niche engineering drives early passage through an immune bottleneck in progression to colorectal cancer. biorxiv.org. https://doi.org/10.1101/623959

Preprint: Model-based tumor subclonal reconstruction

Other

Giulio Caravagna, Timon Heide, Marc Williams, Luis Zapata, Daniel Nichol, Ketevan Chkhaidze, William Cross, George D. Cresswell, Benjamin Werner, Ahmet Acar, Chris P. Barnes, Guido Sanguinetti, Trevor A. Graham and Andrea Sottoriva 2019. Preprint: Model-based tumor subclonal reconstruction. biorxiv.org. https://doi.org/10.1101/586560

Preprint: Evolutionary dynamics of neoantigens in growing tumours

Other

Eszter Lakatos, Marc J. Williams, Ryan O. Schenck, William C. H. Cross, Jacob Househam, Benjamin Werner, Chandler Gatenbee, Mark Robertson-Tessi, Chris P. Barnes, Alexander R. A. Anderson, Andrea Sottoriva and Trevor A. Graham 2019. Preprint: Evolutionary dynamics of neoantigens in growing tumours. biorxiv.org. https://doi.org/10.1101/536433

Characterization and regulation of wild‐type and mutant TASK‐1 two pore domain potassium channels indicated in pulmonary arterial hypertension

Journal article

Cunningham, K.P., Holden, R.G., Escribano‐Subias, P.M., Cogolludo, A., Veale, E.L. and Mathie, A. 2019. Characterization and regulation of wild‐type and mutant TASK‐1 two pore domain potassium channels indicated in pulmonary arterial hypertension. Journal of Physiology. 597 (4), pp. 1087-1101. https://doi.org/10.1113/jp277275

The effect of brisk walking in the fasted versus fed state on metabolic responses, gastrointestinal function, and appetite in healthy men

Journal article

McIver, V.J., Mattin, L.R., Evans, G.H. and Yau, A.M.W. 2019. The effect of brisk walking in the fasted versus fed state on metabolic responses, gastrointestinal function, and appetite in healthy men. International Journal of Obesity. 43, pp. 1691-1700. https://doi.org/10.1038/s41366-018-0215-x

Diurnal influences of fasted and non-fasted brisk walking on gastric emptying rate, metabolic responses, and appetite in healthy males

Journal article

McIver, V.J., Mattin, L.R., Evans, G.H. and Yau, A.M.W. 2019. Diurnal influences of fasted and non-fasted brisk walking on gastric emptying rate, metabolic responses, and appetite in healthy males. Appetite. 143 104411. https://doi.org/10.1016/j.appet.2019.104411

C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

Journal article

Faravelli, G., Raimondi, S., Marchese, L., Partridge, F.A., Soria, C., Mangione, P.P., Canetti, D., Perni, M., Aprile, F.A., Zorzoli, I., Di Schiavi, E., Lomas, D.A., Bellotti, V., Sattelle, D.B. and Giorgetti, S. 2019. C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis. Scientific Reports. 9 19960. https://doi.org/10.1038/s41598-019-56498-5

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies

Journal article

Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M.A., Hayward, R., Ahmad, S.M., Vizcay-Barrena, G., Protti, A., Zammit, P.S., dos Remedios, C.G., Ehler, E., Shah, A.M. and Shanahan, C.M. 2019. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies. JCI Insight. 4 (22) e126315. https://doi.org/10.1172/jci.insight.126315

Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report

Journal article

Daniel Brayson, Alessandra Frigiola and James E. Clark 2019. Dynamic heart rate response to multi-day unsupported ultra-endurance cycle racing: a case report. Experimental Physiology. 104 (2), pp. 174-179. https://doi.org/10.1113/ep087341

Vascular Biology of Superoxide-Generating NADPH Oxidase 5—Implications in Hypertension and Cardiovascular Disease

Journal article

Rhian M. Touyz, Aikaterini Anagnostopoulou, Livia L. Camargo, Francisco J. Rios and Augusto C. Montezano 2019. Vascular Biology of Superoxide-Generating NADPH Oxidase 5—Implications in Hypertension and Cardiovascular Disease. Antioxidants and Redox Signaling. 30 (7), pp. 1027-1040. https://doi.org/10.1089/ars.2018.7583

NOX5: Molecular biology and pathophysiology

Journal article

Rhian Touyz, Aikaterini Anagnostopoulou, Francisco Rios, Augusto C. Montezano and Livia L. Camargo 2019. NOX5: Molecular biology and pathophysiology. Experimental Physiology. 104 (5), pp. 605-616. https://doi.org/10.1113/ep086204

Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease

Other

Lange, S. and Nicholas, A.P. 2019. Special Issue: Peptidylarginine Deiminases and Protein Deimination in Health and Disease. MDPI.

Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA

Book chapter

Mehta, K. and Patel, V.B. 2019. Measurement of 4-Hydroxynonenal (4-HNE) Protein Adducts by ELISA. in: Hancock, J. and Conway, M.E. (ed.) Redox mediated Siganl Transduction. Methods in Molecular Biology New York Humana Press.

A comparison of two widely used physical activity monitoring methods to determine physical activity rates of University employees

Conference paper

Safi, A., Cole, M. and Walker, N. 2019. A comparison of two widely used physical activity monitoring methods to determine physical activity rates of University employees. Public Health Institution Conference. Liverpool John Moore University 04 Jul 2018

The importance of engaging in regular physical activity on health and wellbeing

Conference item

Safi, A. 2019. The importance of engaging in regular physical activity on health and wellbeing. RESFEST Annual Conference. Birmingham City University 03 Jul 2019

Physical activity, health and well-being interventions in the university workplace

Conference item

Safi, A. 2019. Physical activity, health and well-being interventions in the university workplace. 14th Annual Health Conference. Birmingham City University, UK 02 Jul 2019

Promoting Physical Activity Amongst University Employees

Conference item

Safi, A., Kelly, A.L., Cole, M. and Walker, N. 2019. Promoting Physical Activity Amongst University Employees. British Psychological Society (BPS) 2019 Annual Conference. Voco St. John’s Solihull, UK 02 - 03 Dec 2019

An evaluation of physical activity levels amongst university employees

Conference item

Safi, A., Cole, M., Walker, N. and Kelly, A.L. 2019. An evaluation of physical activity levels amongst university employees. British Association Sport and Exercise Sciences (BASES) 2019 Annual Conference. King Power Stadium, Leicester, UK 19 - 20 Nov 2019

The researcher on a mission to get staff exercising in the office

Other

Safi, A. 2019. The researcher on a mission to get staff exercising in the office. Birmingham City University Press Office.

Blog post: Ramadan: Fitness Survival Guide

Other

Safi, A. 2019. Blog post: Ramadan: Fitness Survival Guide. Birmingham City University.

How to fast responsibly during the Muslim holy month

Other

Safi, A. 2019. How to fast responsibly during the Muslim holy month. The Independent.


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