Life Sciences

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HeadProf Alistair Mathie
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Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds

Journal article

Phillips, R.A., Kraev, I. and Lange, S. 2020. Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds. MDPI Biology. 9 (1) 15. https://doi.org/10.3390/biology9010015

Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets

Journal article

Antwi-Baffour, S., Malibha-Pinchbeck, M., Stratton, D., Jorfi, S., Lange, S. and Inal, J.M. 2020. Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets. Journal of Extracellular Vesicles. 9, 2020 (issue 1) 1697124 . https://doi.org/10.1080/20013078.2019.1697124

Carbohydrate intake and ketosis in self-sufficient multi-stage ultramarathon runners

Journal article

Edwards, K., Elliott, B. and Silva, C. 2020. Carbohydrate intake and ketosis in self-sufficient multi-stage ultramarathon runners. Journal of Sports Sciences. 38 (4), pp. 366-374. https://doi.org/10.1080/02640414.2019.1702269

Medicinal plant analysis: A historical and regional discussion of Chinese publication trends and emergent complex techniques

Journal article

Fitzgerald, M., Heinrich, M. and Booker, A. 2020. Medicinal plant analysis: A historical and regional discussion of Chinese publication trends and emergent complex techniques. Frontiers in Pharmacology. 10 1480. https://doi.org/10.3389/fphar.2019.01480

Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.)

Journal article

Magnadóttir, B., Uysal Onganer, P., Kraev, I., Dodds, A.W., Gudmundsdottir, S. and Lange, S. 2020. Extracellular Vesicles, Deiminated Protein Cargo and microRNAs are Novel Serum Biomarkers for Environmental Rearing Temperature in Atlantic Cod (Gadus morhua L.) . Aquaculture Reports. 16 100245. https://doi.org/10.1016/j.aqrep.2019.100245

Deiminated Proteins in Extracellular Vesicles and Serum of Llama (Lama glama) - Novel Insights into Camelid Immunity

Journal article

Criscitiello, M.F., Kraev, I. and Lange, S. 2020. Deiminated Proteins in Extracellular Vesicles and Serum of Llama (Lama glama) - Novel Insights into Camelid Immunity. Molecular Immunology. 117, pp. 37-53 MIMM_5890. https://doi.org/10.1016/j.molimm.2019.10.017

High dose Nitrate ingestion does not improve 40 km cycling time trial performance in trained cyclists

Journal article

Mosher, S., Gough, L., Deb, S., Saunders, B., McNaughton, L., Brown, D. and Sparks, S.A. 2020. High dose Nitrate ingestion does not improve 40 km cycling time trial performance in trained cyclists. Research in Sports Medicine: an International Journal. 28 (1), pp. 138-146. https://doi.org/10.1080/15438627.2019.1586707

The health impact of nature exposure and green exercise across the life course: a pilot study

Journal article

Wood, C. and Smyth, N. 2020. The health impact of nature exposure and green exercise across the life course: a pilot study. International Journal of Environmental Health Research. 30 (2), pp. 226-235. https://doi.org/10.1080/09603123.2019.1593327

Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells

Journal article

Gavinho, B., Sabatke, B., Feijoli, V., Rossi, I., da Silva, J. M., Evans-Osses, I., Palmisano. G., Lange, S. and Ramirez, M.I. 2020. Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells. Frontiers in Cellular and Infection Microbiology. 10 417. https://doi.org/10.3389/fcimb.2020.00417

Populated Collagen Hydrogel and Polyhydroxyalkanoate Composites: Novel Matrices for Cartilage Repair and Regeneration?

Conference poster

De Pascale, C., Marcello, E., Getting, S.J., Roy, I. and Locke, I.C. Forthcoming. Populated Collagen Hydrogel and Polyhydroxyalkanoate Composites: Novel Matrices for Cartilage Repair and Regeneration? OARSI World Congress on Osteoarthritis . Toronto, Canada 02 Mar - 05 May 2019

Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer

Article

Lomax-Browne, Hannah J., Robertson, Claire, Antonopoulos, Aristotelis, Leathem, Anthony J. C., Haslam, Stuart M., Dell, Anne and Dwek, M. 2019. Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer. Interface Focus. 9 (2), p. 20180079 20180079. https://doi.org/10.1098/rsfs.2018.0079

Evaluation of Health Related Quality of Life of HIV/AIDS Patients on Highly Active Antiretroviral Therapy in State House Medical Center Abuja, Nigeria

Journal article

Lawal, I., Tewfik, I. and Amlogu, A. 2019. Evaluation of Health Related Quality of Life of HIV/AIDS Patients on Highly Active Antiretroviral Therapy in State House Medical Center Abuja, Nigeria. Journal of Infectious Disease and Immunology. 1 (9), pp. 1-16.

Non-formal physical education influence on health related physical fitness of children

Journal article

Sarkauskiene, Asta, Noble, Brendon, Kardeliene, Laimute and Noble, Brendon 2019. Non-formal physical education influence on health related physical fitness of children. SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference. 4, pp. 252-267. https://doi.org/10.17770/sie2019vol4.3865

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters

Article

Stephen P.H. Alexander, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan and Jamie A. Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters. British Journal of Pharmacology. 176 (S1), pp. S397-S493. https://doi.org/10.1111/bph.14753

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

Article

Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan and Jamie A. Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes. British Journal of Pharmacology. 176 (S1), pp. S297-S396. https://doi.org/10.1111/bph.14752

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

Article

Stephen P.H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan and Jamie A. Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors. British Journal of Pharmacology. 176 (S1), pp. S21-S141. https://doi.org/10.1111/bph.14748

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets

Article

Stephen P.H. Alexander, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan, O. Peter Buneman, John A. Cidlowski, Arthur Christopoulos, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig and Jamie A. Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. British Journal of Pharmacology. 176, pp. S1-S20. https://doi.org/10.1111/bph.14747

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors

Journal article

Stephen P H Alexander, John A Cidlowski, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan and Jamie A Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors. British Journal of Pharmacology. https://doi.org/10.1111/bph.14750

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors

Journal article

Stephen P.H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan and Jamie A. Davies 2019. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors. British Journal of Pharmacology. 176, pp. S247-S296. https://doi.org/10.1111/bph.14751

The Concise Guide to Pharmacology 2019/20: Ion channels

Journal article

Stephen P.H. Alexander, Alistair Mathie, John A. Peters, Emma L. Veale, Jörg Striessnig, Eamonn Kelly, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Joanna L. Sharman, Christopher Southan and Jamie A. Davies 2019. The Concise Guide to Pharmacology 2019/20: Ion channels. British Journal of Pharmacology. 176 (S1), pp. S142-S228. https://doi.org/10.1111/bph.14749

Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2

Journal article

Wright, P.D., McCoull, D., Walsh, Y., Large, J.M., Hadrys, B.W., Gaurilcikaite, E., Byrom, L., Veale, E.L., Jerman, J. and Mathie, A. 2019. Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2. Biochemical and Biophysical Research Communications. 520 (1), pp. 35-40. https://doi.org/10.1016/j.bbrc.2019.09.093

Editorial: Infection in pulmonary vascular diseases: Would another consortium really be the way to go?

Edited issue

Butrous, G. and Mathie, A. 2019. Editorial: Infection in pulmonary vascular diseases: Would another consortium really be the way to go? Global Cardiology Science & Practice. 2019 (1). https://doi.org/10.21542/gcsp.2019.1

Pharmacologically reversible, loss of function mutations in the TM2 and TM4 inner pore helices of TREK-1 K2P channels

Journal article

Ehab Al-Moubarak, Emma L. Veale and Alistair Mathie 2019. Pharmacologically reversible, loss of function mutations in the TM2 and TM4 inner pore helices of TREK-1 K2P channels. Scientific Reports. 9 12394. https://doi.org/10.1038/s41598-019-48855-1

Enhanced flow-motion complexity of skin microvascular perfusion in Sherpas and lowlanders during ascent to high altitude

Journal article

Carey, D., Thanaj, M., Davies, T., Gilbert-Kawai, E., Mitchell, K., Levett, D.Z.H., Mythen, M.G., Martin, D.S., Grocott, M.P., Chipperfield, A.J. and Clough, G.F. 2019. Enhanced flow-motion complexity of skin microvascular perfusion in Sherpas and lowlanders during ascent to high altitude. Scientific Reports. 9 14391. https://doi.org/10.1038/s41598-019-50774-0

Attractor Reconstruction Analysis for Blood Flow Signals

Conference paper

Thanaj, M., Chipperfield, A.J. and Clough, G.F. 2019. Attractor Reconstruction Analysis for Blood Flow Signals. 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Berlin, Germany 23 - 27 Jul 2019 IEEE . https://doi.org/10.1109/embc.2019.8856856

Multi-domain analysis of microvascular flow motion dynamics in NAFLD

Journal article

Chipperfield, A.J., Thanaj, M., Scorletti, E., Byrne, C.D. and Clough, G.F. 2019. Multi-domain analysis of microvascular flow motion dynamics in NAFLD. Microcirculation. 26 (5) e12538. https://doi.org/10.1111/micc.12538

Integrative assessment of genomic instability and anthropometric inflammatory and micro nutritional biomarkers in childhood obesity

Journal article

Usman, M., Britto, J., Bilkevic, I., Ford-Adams, M., Chapman, S., Glassar, B., Desai, A., Bain, M., Tewfik, I. and Volpi, E. 2019. Integrative assessment of genomic instability and anthropometric inflammatory and micro nutritional biomarkers in childhood obesity. Molecular Cytogenetics. 12 (Suppl.1), p. 30.

A perspective on nanomedicine: focus on cardiovascular medicine

Journal article

Shrestha, S., White, K., Minelli, C., Tewfik, I., Thapa, P. and Tewfik, S. 2019. A perspective on nanomedicine: focus on cardiovascular medicine. International Journal of Food, Nutrition and Public Health. 11 (1/2), pp. 97-119.

Supplementation of Optimum Nutrient-Dense Formula to Modulate HIV Infection in Resource Limited Settings

Journal article

Tewfik, I., Amlogu, A.M. and Wambebe, C. 2019. Supplementation of Optimum Nutrient-Dense Formula to Modulate HIV Infection in Resource Limited Settings. American Journal of Biomedical Science and Research. https://doi.org/10.34297/AJBSR.2019.05.000878

Vitamin D and elevated serum uric acid as novel predictors and prognostic markers for type 2 diabetes mellitus

Journal article

Bener, A., Al-Hamaq, A., Öztürk, M. and Tewfik, I. 2019. Vitamin D and elevated serum uric acid as novel predictors and prognostic markers for type 2 diabetes mellitus. Journal of Pharmacy and Bioallied Sciences . 11 (2), pp. 127-132. https://doi.org/10.4103/jpbs.JPBS_240_18

Innovative Nutritional approach to attenuate the progression of HIV to AIDS among People Living with HIV (PLWH): A study based in Abuja, Nigeria

Journal article

Amlogu, A. M., Tewfik, S., Wambebe, C. and Tewfik, I. 2019. Innovative Nutritional approach to attenuate the progression of HIV to AIDS among People Living with HIV (PLWH): A study based in Abuja, Nigeria. Journal of Advance Research in Medical & Health Science. 5 (1). https://doi.org/10.53555/nnmhs.v5i1.600

Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants

Journal article

Alasdair T. M. Hubbard, Nazila Jafari, Nicholas Feasey, Jennifer L. Rohn and Adam P. Roberts 2019. Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants. Frontiers in Microbiology. 10 2001. https://doi.org/10.3389/fmicb.2019.02001

Cellular senescence in populations of postnatal brain Neural Stem Cells

Article

Anesti, M., Dimitriou, C., Gorgoulis, V. and Kazanis, I. 2019. Cellular senescence in populations of postnatal brain Neural Stem Cells. GLIA. 67 (S1), pp. E503-E504. https://doi.org/10.1002/glia.23675

Genetic studies of MRI liver fat content identify susceptibility variants with variable metabolic effects

Article

Parisinos, Constantinos, Wilman, Henry, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Hingorani, Aroon, Patel, Riyaz, Hemingway, Harry, Banerjee, Rajarshi and Yaghootkar, Hanieh 2019. Genetic studies of MRI liver fat content identify susceptibility variants with variable metabolic effects. Gut. 68 (Supplement 2), p. A110. https://doi.org/10.1136/gutjnl-2019-bsgabstracts.208

PTU-028 Genome-wide association study of MRI liver iron content in UK biobank identifies 3 susceptibility variants

Article

Parisinos, Constantinos, Wilman, Henry, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Hingorani, Aroon, Patel, Riyaz, Hemingway, Harry, Banerjee, Rajarshi and Yaghootkar, Hanieh 2019. PTU-028 Genome-wide association study of MRI liver iron content in UK biobank identifies 3 susceptibility variants. Gut. 68, pp. A125-A126. https://doi.org/10.1136/gutjnl-2019-bsgabstracts.237

Genome-wide association study of MRI liver iron content in 9,800 individuals yields new insights into its link with hepatic and extrahepatic diseases

Article

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Hingorani, A., Mahajan, A., Patel, R., Hemingway, H., Franks, P. W., Bell, J., Banerjee, R. and Yaghootkar, H. 2019. Genome-wide association study of MRI liver iron content in 9,800 individuals yields new insights into its link with hepatic and extrahepatic diseases. European Journal of Human Genetics. 27 (Supplment 2), p. 1148 Meeting Abstract C21.5.

Subcutaneous Abdominal Fat Has a Stronger Association with Prediabetes than Visceral Fat in Young Indians

Article

Wagh, Rucha H., Bawdekar, Rupali U., Alenaini, Wareed, Thomas, Elizabeth L., Bell, Jimmy David and Yajnik, Chittaranjan S. 2019. Subcutaneous Abdominal Fat Has a Stronger Association with Prediabetes than Visceral Fat in Young Indians. Diabetes. 68 (Supplement 1), pp. 2106-P. https://doi.org/10.2337/db19-2106-p

Genome-wide association studies of abdominal MRI scans identifies loci associated with liver fat and liver iron in the UK Biobank

Article

Wilman, Henry, Parisinos, Constantinos, Kelly, Matt, Neubauer, Stefan, Thomas, Louise, Bell, Jimmy, Banerjee, Rajarshi, Yaghootkar, Hanieh and Thomas, E. Louise 2019. Genome-wide association studies of abdominal MRI scans identifies loci associated with liver fat and liver iron in the UK Biobank. Journal of Hepatology. 70 (1, Supplement) E315. https://doi.org/10.1016/s0618-8278(19)30236-1

Knowledge and Attitude Towards Liver Cancer and Liver Cancer Screening Among HBV and HCV Patients in Vientiane, Lao PDR: a cross Sectional Study

Journal article

Cheung, Diana, Khounvisith, Vilaysone, Sitbounlang, Philavanh, Sathathone, Douangprachanh, Virachith, Siriphone, Phetsamone, Arounlangsy, Paboriboune, Phimpha and Black, Antony P. 2019. Knowledge and Attitude Towards Liver Cancer and Liver Cancer Screening Among HBV and HCV Patients in Vientiane, Lao PDR: a cross Sectional Study. Hepatology. 70 (S1), p. 627. https://doi.org/10.1002/hep.30941

Seroprotection at different levels of the healthcare system after routine vaccination with diphtheria-tetanus-pertussis whole cell--hepatitis B--haemophilus influenzae type B in Lao People’s Democratic Republic

Journal article

Hefele, Lisa, Syphan, Sengdavanh, Xayavong, Dalouny, Homsana, Anousin, Kleine, Daria, Chanthavilay, Phetsavanh, Nouanthong, Phonethipsavanh, Xaydalasouk, Kinnaly, Phathammavong, Outavong, Billamay, Somxay, Xeuatvongsa, Anonh, Reinharz, Daniel, Muller, Claude P. and Black, Anthony P. 2019. Seroprotection at different levels of the healthcare system after routine vaccination with diphtheria-tetanus-pertussis whole cell--hepatitis B--haemophilus influenzae type B in Lao People’s Democratic Republic. Clinical Infectious Diseases. 69 (12), pp. 2136-2144. https://doi.org/10.1093/cid/ciz143


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