Life Sciences

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HeadProf Alistair Mathie
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Evaluation of oxidative DNA damage, genome instability and accelerated genomic ageing in childhood obesity

Conference poster

Usman, M. and Volpi, E. 2017. Evaluation of oxidative DNA damage, genome instability and accelerated genomic ageing in childhood obesity. The Human Genome in Healthcare - The Genetics Society. The Royal Society 23 - 24 Nov 2017

In situ hybridization: key concepts and applications

Book chapter

Warford, A. and Volpi, E. 2017. In situ hybridization: key concepts and applications. in: Orchard, G.R. and Nation, B. (ed.) Histopathology Oxford Oxford University Press. pp. 298-317

How to lose weight well television series

Other

Newell, M. 2017. How to lose weight well television series. Channel Four Television.

Phage typing or CRISPR typing for epidemiological surveillance of Salmonella Typhimurium?

Article

Mohammed, M. 2017. Phage typing or CRISPR typing for epidemiological surveillance of Salmonella Typhimurium? BMC Research Notes. 10, p. 578 578. https://doi.org/10.1186/s13104-017-2878-0

RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

Journal article

Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, R., Marini, V., Ferrari, S., Hickson, I.D., Krejci, L. and Janscak, P. 2017. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Molecular Cell. 66 (5), pp. 658-671. https://doi.org/10.1016/j.molcel.2017.05.006

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Journal article

Milne, R.L., Kuchenbaecker, K.B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Simard, J., Dwek, M. and Presneau, Nadège 2017. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics. 49, pp. 1767-1778. https://doi.org/10.1038/ng.3785

Association analysis identifies 65 new breast cancer risk loci

Journal article

Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M.K., Wang, Q., Tyrer, J., Dicks, E., Easton, D.F., Dwek, M. and Presneau, Nadège 2017. Association analysis identifies 65 new breast cancer risk loci. Nature. 551, pp. 92-94. https://doi.org/10.1038/nature24284

Efficacy Of The Quadrivalent HPV Vaccine In Cervical Cancer Prevention Strategy In The Gambia

Conference poster

Bah Camara, H., Anyanwu, M., Banja, F., Mboob-Suun, K., Ceesay, F., Wright, E. and Kimmitt, P.T. 2017. Efficacy Of The Quadrivalent HPV Vaccine In Cervical Cancer Prevention Strategy In The Gambia. EUROGIN17. Amsterdam 08 - 11 Oct 2017

Data-driven computational modeling of CA1 hippocampal principal cells and interneurons

Conference poster

Lange, S., migliore, S. and Lupascu, A.C. 2017. Data-driven computational modeling of CA1 hippocampal principal cells and interneurons. 26th Annual Computational Neuroscience Meeting (CNS*2017). Antwerp, Belgium 15 - 20 Jul 2017 BioMed Central. https://doi.org/10.1186/s12868-017-0372-1

Polymers imprinted with three REG1B peptides for electrochemical determination of Regenerating Protein 1B, a urinary biomarker for pancreatic ductal adenocarcinoma

Journal article

Jurcevic, S., Lee, M-H., Thomas, J.L., Liao, C-L., Crnogorac-Jurcevic, T. and Lin, H-Y. 2017. Polymers imprinted with three REG1B peptides for electrochemical determination of Regenerating Protein 1B, a urinary biomarker for pancreatic ductal adenocarcinoma. Microchimica Acta. 184 (6), p. 1773–1780. https://doi.org/10.1007/s00604-017-2169-4

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin

Journal article

Dorofejeva, O. and Barr, A.J. 2017. Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin. PLoS ONE. 12 (9) e0184574. https://doi.org/10.1371/journal.pone.0184574

Faecal Calprotectin and a Twenty-Four-Parameter Questionnaire in Autistic Children with Gastrointestinal Symptoms

Article

Bramati-castellarin, I., Patel, V.B. and Drysdale, I.P. 2017. Faecal Calprotectin and a Twenty-Four-Parameter Questionnaire in Autistic Children with Gastrointestinal Symptoms. SM Journal of Psychiatry & Mental Health. 2 (1), p. 1009 1009.

Chondroprotection by urocortin involves blockade of a mechanosensitive piezo1 ion channel: novel, exploitable pathways for the treatment and prevention of osteoarthritis?

Conference paper

Lawrence, K.M., Jones, R.C., Jackson, T.R., Baylie, R.L., Abbot, B., Bruhn-Olszewska, B, Board, T.N., Locke, I.C., Richardson, S.M and Townsend, P.A. 2017. Chondroprotection by urocortin involves blockade of a mechanosensitive piezo1 ion channel: novel, exploitable pathways for the treatment and prevention of osteoarthritis? OARSI 2017 World Congress on Osteoarthritis. Las Vegas, USA. 17 - 20 Apr 2017 Elsevier. https://doi.org/10.1016/j.joca.2017.02.124

Urocortin protects chondrocytes from acute trauma in articular cartilage

Conference poster

Jones, R.C., Jackson, TR, Locke, I.C., Board, T.N., Richardson, S.M., Townsend, P.A. and Lawrence, K.M. 2017. Urocortin protects chondrocytes from acute trauma in articular cartilage. OARSI 2017 World Congress on Osteoarthritis. Las Vegas, USA 27 - 30 Apr 2017 Elsevier. https://doi.org/10.1016/j.joca.2017.02.291

Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets

Article

Umpleby, A.M., Shoajee-Moradie, F., Fielding, F., Li, X., Marino, A., Alsini, N, Isherwood, C, Jackson, N.C., Ahmad, A., Stolinski, M., Lovegrove, J.A., Johnsen, S., Mendis, A., Wright, J., Wilinska, M.E., Hovorka, R., Bell, J.D., Thomas, E.L., Frost, G.S. and Griffin, B.A. 2017. Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets. Clinical Science. 131 (21), pp. 2561-2573. https://doi.org/10.1042/CS20171208

The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise

Conference poster

Kyriakidou, Y., Kantorovich, R.C., Bell, J.D., Monterisi, S. and Dolci, A. 2017. The Potential of Omega-3 Supplementation to Reduce Muscle-Inflammation after Muscle-Damaging Exercise. ACSM Annual Meeting, World Congress on Exercise is Medicine & World Congress on the Basic Science of Exercise and the Brain. Denver, Colorado 30 May - 03 Jun 2017 American College of Sports Medicine. https://doi.org/10.1249/01.mss.0000518523.15295.1c

PhytoCloud: A gamified Mobile Web Application to modulate diet and physical activity of women with breast cancer

Conference paper

Economou, D., Dwek, M., Elliott, B., Ramezanian Kalahroudi, M. and Azimi, T. 2017. PhytoCloud: A gamified Mobile Web Application to modulate diet and physical activity of women with breast cancer. IEEE 30th International Symposium on Computer-Based Medical Systems. Thessaloniki, Greece 22 Jun - 24 Sep 2017 IEEE . https://doi.org/10.1109/CBMS.2017.164

Evaluation of the Reading Well Books on Prescription Shelf Help scheme for young people

Project report

Polley, M.J. and Kovandzic, M. 2017. Evaluation of the Reading Well Books on Prescription Shelf Help scheme for young people.

Practice Based Evidence

Conference paper

Green, J. 2017. Practice Based Evidence. National Institute of Medical Herbalists 153rd Annual Conference. Stratford-upon-Avon 13 - 14 Oct 2017

Changing with Herbs: a pilot randomised controlled trial of Western herbal practice for the menopause

Conference paper

Green, J. 2017. Changing with Herbs: a pilot randomised controlled trial of Western herbal practice for the menopause. Treating Women's Health With Herbal Medicine. Chelsea Physic Garden, London 22 May 2017

Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects

Journal article

Brody, L.P., Sahuri Arisoylu, M., Parkinson, J.R., Parkes, H.G., So, P-W, Hajji, N, Thomas, E.L., Frost, G.S., Miller, A.D. and Bell, J.D. 2017. Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects. International Journal of Nanomedicine. 12, pp. 6677-6685. https://doi.org/10.2147/IJN.S135968

GPs’ perceptions of resilience training: a qualitative study

Journal article

Cheshire, A., Hughes, J., Lewith, G., Panagioti, M, Peters, D., Simon, C. and Ridge, Damien T. 2017. GPs’ perceptions of resilience training: a qualitative study. British Journal of General Practice. 67 (663), pp. e709-e715. https://doi.org/10.3399/bjgp17X692561

Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients

Article

Al-Daghri, N.M., Mohammed, A.K., Al-Attas, O.S., Ansari, M.G.A., Wani, K., Hussain, S.D., Sabico, S., Tripathi, G. and Alokail, M.S. 2017. Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients. Scientific Reports. 7, p. 8280 8280. https://doi.org/10.1038/s41598-017-08621-7

Are sage, rosemary and lemon balm effective interventions in dementia? A narrative review of the clinical evidence

Journal article

Shinjyo, N. and Green, J. 2017. Are sage, rosemary and lemon balm effective interventions in dementia? A narrative review of the clinical evidence. European Journal of Integrative Medicine. 15, pp. 83-96. https://doi.org/10.1016/j.eujim.2017.08.013

HFE mRNA expression is responsive to intracellular and extracellular iron loading: short communication

Journal article

Mehta, K., Farnaud, S. and Patel, V.B. 2017. HFE mRNA expression is responsive to intracellular and extracellular iron loading: short communication. Molecular Biology Reports. 44 (5), pp. 399-403. https://doi.org/10.1007/s11033-017-4123-2

Making Sense of Social Prescribing

Technical report

Polley, M.J., Fleming, J., Anfilogoff, T. and Carpenter, A. 2017. Making Sense of Social Prescribing. London University of Westminster.

Integrative Whole Person Oncology Care in the UK

Article

Zollman, C., Walther, A., Seers, H., Jolliffe, R. and Polley, M.J. 2017. Integrative Whole Person Oncology Care in the UK. JNCI Monographs. 2017 (52), p. lgx002 lgx002. https://doi.org/10.1093/jncimonographs/lgx002

Development of a two day wellbeing course for supporters of teenagers and young adults (TYA) with cancer

Conference poster

Jolliffe, R., Cargill, J., Polley, M.J., French, H., Hardman, F., Seers, H. and Baker, L. 2017. Development of a two day wellbeing course for supporters of teenagers and young adults (TYA) with cancer. TYAC BRIGHTLIGHT Conference. Leeds, UK 06 - 07 Jul 2017

The challenge of biocompatibility evaluation of biocomposites

Book chapter

Iqbal, H.M.N. and Keshavarz, T. 2017. The challenge of biocompatibility evaluation of biocomposites. in: Ambrosio, L. (ed.) Biomedical Composites. 2nd ed. Woodhead Publishing. pp. 303-334

Evaluating Inflammatory and Genotoxic Consequences of Adiposity in Adolescents: a Non-Invasive Approach

Conference paper

Usman, M. and Volpi, E. 2017. Evaluating Inflammatory and Genotoxic Consequences of Adiposity in Adolescents: a Non-Invasive Approach. The 12th International Conference and 5th Asian Congress on Environmental Mutagens. Korea 12 - 16 Nov 2017 Korean Environmental Mutagen Society.

Why should Britain Care about Salmonella Dublin?

Other

Mohammed, M. 2017. Why should Britain Care about Salmonella Dublin?

Whole genome sequencing reveals the secrets of Salmonella Dublin invasome

Conference poster

Mohammed, M., Le Hello, S., Leekitcharoenphon, P. and Hendriksen, R. 2017. Whole genome sequencing reveals the secrets of Salmonella Dublin invasome. European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Vienna, Austria 25 Apr - 21 Jul 2017

Genome Instability in Childhood Obesity – a potential role for bariatric surgery in cancer prevention?

Conference poster

Usman, M. and Volpi, E. 2017. Genome Instability in Childhood Obesity – a potential role for bariatric surgery in cancer prevention? Severe Paediatric Obesity: Current Medical and Surgical Management Paradigms - A Global Perspective. London 18 Jul 2017 International Consortium of Adolescent Bariatric Surgeons (ICABS).

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1

Journal article

Lawrence, K.M., Jones, R.C., Jackson, T.R., Baylie, R.L., Abbott, B., Bruhn-Olszewska, B., Board, T.N., Locke, I.C., Richardson, S.M. and Townsend, P.A. 2017. Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1. Scientific Reports. 7 (1), p. 5147 5147. https://doi.org/10.1038/s41598-017-04367-4

The invasome of Salmonella Dublin as revealed by whole genome sequencing

Journal article

Mohammed, M., Le Hello, S., Leekitcharoenphon, P. and Hendriksen, R. 2017. The invasome of Salmonella Dublin as revealed by whole genome sequencing . BMC Infectious Diseases. 17, p. 544 544. https://doi.org/10.1186/s12879-017-2628-x

Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold

Article

Basnett, P., Lukasiewicz, B., Marcello, E., Kaur, H., Knowles, J.C. and Roy, I. 2017. Production of a novel medium chain length Poly(3-hydroxyalkanoate) using unprocessed biodiesel waste and its evaluation as a tissue engineering scaffold. Microbial Biotechnology. 10 (6), pp. 1384-1399. https://doi.org/10.1111/1751-7915.12782

Alcohol metabolism: implications for nutrution and health

Book chapter

Patel, V.B. and Preedy, V.R. 2017. Alcohol metabolism: implications for nutrution and health. in: Geissler, C. and Powers, H. (ed.) Human Nutrition, 13th Edition Oxford Oxford University Press. pp. 216-235

Ethnic differences in the +405 and −460 vascular endothelial growth factor polymorphisms and peripheral neuropathy in patients with diabetes residing in a North London, community in the United Kingdom

Journal article

Zitouni, K., Tinworth, L. and Earle, K.A. 2017. Ethnic differences in the +405 and −460 vascular endothelial growth factor polymorphisms and peripheral neuropathy in patients with diabetes residing in a North London, community in the United Kingdom. BMC Neurology. 17, p. 125 125. https://doi.org/10.1186/s12883-017-0905-3

Activation of the pro-resolving receptor Fpr2 attenuates inflammatory microglial activation

Conference poster

Wickstead, E., Getting, S.J., Biggs, C.S. and McArthur, S. 2017. Activation of the pro-resolving receptor Fpr2 attenuates inflammatory microglial activation. BNA Festival of Neuroscience. Birmingham 10 - 13 Apr 2017 Sage. https://doi.org/10.1177/2398212817705279

The effect of the selective MC3 agonist PG990 on high density human chondrocytes micromass cultures activated by TNF-alpha

Conference poster

Getting, S.J., Can, V.C., Locke, I.C. and Grieco, P 2017. The effect of the selective MC3 agonist PG990 on high density human chondrocytes micromass cultures activated by TNF-alpha. World Congress on Inflammation. London 08 - 12 Jul 2017


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